| Full name: CD1c molecule | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1q23.1 | ||
| Entrez ID: 911 | HGNC ID: HGNC:1636 | Ensembl Gene: ENSG00000158481 | OMIM ID: 188340 |
| Drug and gene relationship at DGIdb | |||
Expression of CD1C:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CD1C | 911 | 205987_at | -0.4341 | 0.5043 | |
| GSE20347 | CD1C | 911 | 205987_at | -0.5075 | 0.0010 | |
| GSE23400 | CD1C | 911 | 205987_at | -0.1777 | 0.0000 | |
| GSE26886 | CD1C | 911 | 205987_at | -1.4148 | 0.0000 | |
| GSE29001 | CD1C | 911 | 205987_at | -0.6470 | 0.0011 | |
| GSE38129 | CD1C | 911 | 205987_at | -0.5595 | 0.0000 | |
| GSE45670 | CD1C | 911 | 205987_at | -1.0648 | 0.0001 | |
| GSE63941 | CD1C | 911 | 205987_at | 0.1349 | 0.4214 | |
| GSE77861 | CD1C | 911 | 205987_at | -0.3740 | 0.0025 | |
| SRP064894 | CD1C | 911 | RNAseq | -1.0068 | 0.0109 | |
| SRP133303 | CD1C | 911 | RNAseq | -2.1789 | 0.0000 | |
| SRP159526 | CD1C | 911 | RNAseq | -1.6406 | 0.0676 | |
| SRP193095 | CD1C | 911 | RNAseq | -1.2187 | 0.0006 | |
| SRP219564 | CD1C | 911 | RNAseq | -0.8656 | 0.1488 | |
| TCGA | CD1C | 911 | RNAseq | -0.1456 | 0.6965 |
Upregulated datasets: 0; Downregulated datasets: 5.
Survival by CD1C expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of CD1C:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CD1C | 911 | 9 | 1 | 20 | |
| GSE20123 | CD1C | 911 | 9 | 1 | 20 | |
| GSE43470 | CD1C | 911 | 7 | 2 | 34 | |
| GSE46452 | CD1C | 911 | 2 | 1 | 56 | |
| GSE47630 | CD1C | 911 | 14 | 0 | 26 | |
| GSE54993 | CD1C | 911 | 0 | 5 | 65 | |
| GSE54994 | CD1C | 911 | 16 | 0 | 37 | |
| GSE60625 | CD1C | 911 | 0 | 0 | 11 | |
| GSE74703 | CD1C | 911 | 7 | 2 | 27 | |
| GSE74704 | CD1C | 911 | 4 | 1 | 15 | |
| TCGA | CD1C | 911 | 39 | 3 | 54 |
Total number of gains: 107; Total number of losses: 16; Total Number of normals: 365.
Somatic mutations of CD1C:
Generating mutation plots.
Highly correlated genes for CD1C:
Showing top 20/956 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CD1C | DOCK8 | 0.750598 | 3 | 0 | 3 |
| CD1C | RASSF5 | 0.747523 | 3 | 0 | 3 |
| CD1C | A2ML1 | 0.740547 | 3 | 0 | 3 |
| CD1C | CAPN14 | 0.722047 | 3 | 0 | 3 |
| CD1C | VSIG10L | 0.715425 | 3 | 0 | 3 |
| CD1C | CGNL1 | 0.712529 | 4 | 0 | 4 |
| CD1C | ZHX1 | 0.707679 | 3 | 0 | 3 |
| CD1C | AIF1L | 0.705311 | 3 | 0 | 3 |
| CD1C | SLC44A3 | 0.705176 | 4 | 0 | 4 |
| CD1C | FMN1 | 0.70506 | 4 | 0 | 4 |
| CD1C | PPM1K | 0.704326 | 4 | 0 | 4 |
| CD1C | PRSS27 | 0.703571 | 3 | 0 | 3 |
| CD1C | CD1A | 0.700806 | 8 | 0 | 6 |
| CD1C | INPP1 | 0.700585 | 5 | 0 | 5 |
| CD1C | MUC15 | 0.699625 | 3 | 0 | 3 |
| CD1C | SH3BGRL2 | 0.698325 | 4 | 0 | 3 |
| CD1C | RAF1 | 0.698003 | 3 | 0 | 3 |
| CD1C | MCEE | 0.694748 | 3 | 0 | 3 |
| CD1C | USP16 | 0.691942 | 3 | 0 | 3 |
| CD1C | PHYHD1 | 0.690955 | 3 | 0 | 3 |
For details and further investigation, click here
