| Full name: Rho family GTPase 3 | Alias Symbol: RhoE|Rho8 | ||
| Type: protein-coding gene | Cytoband: 2q23.3 | ||
| Entrez ID: 390 | HGNC ID: HGNC:671 | Ensembl Gene: ENSG00000115963 | OMIM ID: 602924 |
| Drug and gene relationship at DGIdb | |||
Expression of RND3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RND3 | 390 | 212724_at | -0.2701 | 0.5665 | |
| GSE20347 | RND3 | 390 | 212724_at | -1.2619 | 0.0000 | |
| GSE23400 | RND3 | 390 | 212724_at | -1.0922 | 0.0000 | |
| GSE26886 | RND3 | 390 | 212724_at | -2.4918 | 0.0000 | |
| GSE29001 | RND3 | 390 | 212724_at | -1.0950 | 0.0075 | |
| GSE38129 | RND3 | 390 | 212724_at | -0.8554 | 0.0011 | |
| GSE45670 | RND3 | 390 | 212724_at | -0.4234 | 0.1343 | |
| GSE53622 | RND3 | 390 | 3767 | -1.0578 | 0.0000 | |
| GSE53624 | RND3 | 390 | 3767 | -1.4867 | 0.0000 | |
| GSE63941 | RND3 | 390 | 212724_at | -3.7138 | 0.0004 | |
| GSE77861 | RND3 | 390 | 212724_at | -0.3868 | 0.4279 | |
| GSE97050 | RND3 | 390 | A_23_P142849 | -0.6685 | 0.1065 | |
| SRP007169 | RND3 | 390 | RNAseq | -2.9394 | 0.0000 | |
| SRP008496 | RND3 | 390 | RNAseq | -2.7272 | 0.0000 | |
| SRP064894 | RND3 | 390 | RNAseq | -1.8347 | 0.0000 | |
| SRP133303 | RND3 | 390 | RNAseq | -1.2740 | 0.0000 | |
| SRP159526 | RND3 | 390 | RNAseq | -1.1521 | 0.0000 | |
| SRP193095 | RND3 | 390 | RNAseq | -1.4368 | 0.0001 | |
| SRP219564 | RND3 | 390 | RNAseq | -1.3368 | 0.0046 | |
| TCGA | RND3 | 390 | RNAseq | 0.0277 | 0.7467 |
Upregulated datasets: 0; Downregulated datasets: 14.
Survival by RND3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RND3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RND3 | 390 | 3 | 3 | 24 | |
| GSE20123 | RND3 | 390 | 3 | 3 | 24 | |
| GSE43470 | RND3 | 390 | 3 | 1 | 39 | |
| GSE46452 | RND3 | 390 | 1 | 4 | 54 | |
| GSE47630 | RND3 | 390 | 5 | 3 | 32 | |
| GSE54993 | RND3 | 390 | 0 | 5 | 65 | |
| GSE54994 | RND3 | 390 | 11 | 2 | 40 | |
| GSE60625 | RND3 | 390 | 0 | 3 | 8 | |
| GSE74703 | RND3 | 390 | 2 | 1 | 33 | |
| GSE74704 | RND3 | 390 | 3 | 1 | 16 | |
| TCGA | RND3 | 390 | 21 | 8 | 67 |
Total number of gains: 52; Total number of losses: 34; Total Number of normals: 402.
Somatic mutations of RND3:
Generating mutation plots.
Highly correlated genes for RND3:
Showing top 20/1053 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RND3 | SYTL4 | 0.807395 | 3 | 0 | 3 |
| RND3 | TBC1D20 | 0.761696 | 3 | 0 | 3 |
| RND3 | GPCPD1 | 0.757417 | 3 | 0 | 3 |
| RND3 | SLC46A2 | 0.741636 | 5 | 0 | 4 |
| RND3 | TPD52L2 | 0.740729 | 3 | 0 | 3 |
| RND3 | CPEB4 | 0.728286 | 6 | 0 | 6 |
| RND3 | TMEM154 | 0.726705 | 4 | 0 | 4 |
| RND3 | S100A16 | 0.719888 | 4 | 0 | 4 |
| RND3 | ANKRD37 | 0.719534 | 3 | 0 | 3 |
| RND3 | BIVM | 0.719497 | 3 | 0 | 3 |
| RND3 | RAB11A | 0.718182 | 9 | 0 | 9 |
| RND3 | CA13 | 0.717064 | 3 | 0 | 3 |
| RND3 | ATP13A4 | 0.716545 | 3 | 0 | 3 |
| RND3 | LRRFIP2 | 0.713836 | 10 | 0 | 10 |
| RND3 | MAP4K4 | 0.703028 | 3 | 0 | 3 |
| RND3 | CTTNBP2 | 0.702994 | 4 | 0 | 4 |
| RND3 | PLK3 | 0.701636 | 8 | 0 | 8 |
| RND3 | ZNF547 | 0.701554 | 4 | 0 | 4 |
| RND3 | CASC3 | 0.700953 | 3 | 0 | 3 |
| RND3 | EMP1 | 0.699702 | 9 | 0 | 7 |
For details and further investigation, click here
