RNF10

 

Full name: ring finger protein 10 Alias Symbol: KIAA0262|RIE2
Type: protein-coding gene Cytoband: 12q24.31
Entrez ID: 9921 HGNC ID: HGNC:10055 Ensembl Gene: ENSG00000022840 OMIM ID: 615998
Drug and gene relationship at DGIdb

 

Expression of RNF10:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 RNF10 9921 207801_s_at -0.2268 0.4899
GSE20347 RNF10 9921 207801_s_at -0.8126 0.0000
GSE23400 RNF10 9921 207801_s_at -0.5733 0.0000
GSE26886 RNF10 9921 207801_s_at -1.0796 0.0002
GSE29001 RNF10 9921 207801_s_at -0.7929 0.0023
GSE38129 RNF10 9921 207801_s_at -0.6823 0.0000
GSE45670 RNF10 9921 207801_s_at -0.3206 0.0752
GSE53622 RNF10 9921 77316 -0.5708 0.0000
GSE53624 RNF10 9921 77316 -0.6421 0.0000
GSE63941 RNF10 9921 207801_s_at -0.1997 0.5464
GSE77861 RNF10 9921 207801_s_at -0.6350 0.0008
GSE97050 RNF10 9921 A_24_P261724 -0.3558 0.1674
SRP007169 RNF10 9921 RNAseq -1.7043 0.0004
SRP008496 RNF10 9921 RNAseq -1.7946 0.0000
SRP064894 RNF10 9921 RNAseq -1.0291 0.0000
SRP133303 RNF10 9921 RNAseq -0.5960 0.0000
SRP159526 RNF10 9921 RNAseq -0.6547 0.0055
SRP193095 RNF10 9921 RNAseq -0.8972 0.0000
SRP219564 RNF10 9921 RNAseq -0.8815 0.0023
TCGA RNF10 9921 RNAseq -0.1432 0.0003

Upregulated datasets: 0; Downregulated datasets: 4.  


 

Survival by RNF10 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of RNF10:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 RNF10 9921 6 2 22
GSE20123 RNF10 9921 6 2 22
GSE43470 RNF10 9921 2 2 39
GSE46452 RNF10 9921 9 1 49
GSE47630 RNF10 9921 9 3 28
GSE54993 RNF10 9921 0 5 65
GSE54994 RNF10 9921 7 6 40
GSE60625 RNF10 9921 0 0 11
GSE74703 RNF10 9921 2 1 33
GSE74704 RNF10 9921 3 2 15
TCGA RNF10 9921 20 11 65

Total number of gains: 64; Total number of losses: 35; Total Number of normals: 389.  


 

Somatic mutations of RNF10:

 

Generating mutation plots.

 

Highly correlated genes for RNF10:

 

Showing top 20/1632 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
RNF10ZNRF10.830315303
RNF10RMND5B0.80459411010
RNF10GDPD30.797959909
RNF10RAB5B0.79760311011
RNF10CTTNBP2NL0.791133606
RNF10MXD10.789906909
RNF10CLIC30.78544707
RNF10RANBP90.78325610010
RNF10MPP70.78283606
RNF10ULK30.782478606
RNF10SLC46A20.78173606
RNF10SORT10.78139210010
RNF10A2ML10.77644505
RNF10TRIP100.77618411011
RNF10FAM214A0.776007505
RNF10ACOX30.77429110010
RNF10EHD30.76965910010
RNF10ZNF2140.767399303
RNF10BLOC1S10.767348909
RNF10SH3GLB10.766705909

For details and further investigation, click here