| Full name: thyroid hormone receptor interactor 10 | Alias Symbol: STP|HSTP|CIP4 | ||
| Type: protein-coding gene | Cytoband: 19p13.3 | ||
| Entrez ID: 9322 | HGNC ID: HGNC:12304 | Ensembl Gene: ENSG00000125733 | OMIM ID: 604504 |
| Drug and gene relationship at DGIdb | |||
TRIP10 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04910 | Insulin signaling pathway |
Expression of TRIP10:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TRIP10 | 9322 | 202734_at | -1.2754 | 0.0341 | |
| GSE20347 | TRIP10 | 9322 | 202734_at | -2.0346 | 0.0000 | |
| GSE23400 | TRIP10 | 9322 | 202734_at | -1.5714 | 0.0000 | |
| GSE26886 | TRIP10 | 9322 | 202734_at | -1.8161 | 0.0000 | |
| GSE29001 | TRIP10 | 9322 | 202734_at | -1.3032 | 0.0000 | |
| GSE38129 | TRIP10 | 9322 | 202734_at | -1.7503 | 0.0000 | |
| GSE45670 | TRIP10 | 9322 | 202734_at | -0.7294 | 0.0064 | |
| GSE53622 | TRIP10 | 9322 | 70818 | -2.0397 | 0.0000 | |
| GSE53624 | TRIP10 | 9322 | 161288 | -2.1457 | 0.0000 | |
| GSE63941 | TRIP10 | 9322 | 202734_at | 2.4211 | 0.0022 | |
| GSE77861 | TRIP10 | 9322 | 202734_at | -1.4235 | 0.0008 | |
| GSE97050 | TRIP10 | 9322 | A_23_P50349 | -0.6823 | 0.1236 | |
| SRP007169 | TRIP10 | 9322 | RNAseq | -4.1556 | 0.0000 | |
| SRP008496 | TRIP10 | 9322 | RNAseq | -3.9954 | 0.0000 | |
| SRP064894 | TRIP10 | 9322 | RNAseq | -2.4005 | 0.0000 | |
| SRP133303 | TRIP10 | 9322 | RNAseq | -2.3691 | 0.0000 | |
| SRP159526 | TRIP10 | 9322 | RNAseq | -2.7323 | 0.0000 | |
| SRP193095 | TRIP10 | 9322 | RNAseq | -2.5815 | 0.0000 | |
| SRP219564 | TRIP10 | 9322 | RNAseq | -2.0362 | 0.0001 | |
| TCGA | TRIP10 | 9322 | RNAseq | 0.0430 | 0.5800 |
Upregulated datasets: 1; Downregulated datasets: 16.
Survival by TRIP10 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TRIP10:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TRIP10 | 9322 | 5 | 3 | 22 | |
| GSE20123 | TRIP10 | 9322 | 4 | 2 | 24 | |
| GSE43470 | TRIP10 | 9322 | 2 | 6 | 35 | |
| GSE46452 | TRIP10 | 9322 | 47 | 1 | 11 | |
| GSE47630 | TRIP10 | 9322 | 5 | 7 | 28 | |
| GSE54993 | TRIP10 | 9322 | 16 | 3 | 51 | |
| GSE54994 | TRIP10 | 9322 | 6 | 14 | 33 | |
| GSE60625 | TRIP10 | 9322 | 9 | 0 | 2 | |
| GSE74703 | TRIP10 | 9322 | 2 | 4 | 30 | |
| GSE74704 | TRIP10 | 9322 | 1 | 2 | 17 | |
| TCGA | TRIP10 | 9322 | 9 | 19 | 68 |
Total number of gains: 106; Total number of losses: 61; Total Number of normals: 321.
Somatic mutations of TRIP10:
Generating mutation plots.
Highly correlated genes for TRIP10:
Showing top 20/1646 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TRIP10 | EPS8L2 | 0.906296 | 10 | 0 | 10 |
| TRIP10 | VSIG10L | 0.889466 | 6 | 0 | 6 |
| TRIP10 | CRCT1 | 0.883794 | 10 | 0 | 10 |
| TRIP10 | GYS2 | 0.88378 | 10 | 0 | 10 |
| TRIP10 | SCNN1B | 0.867792 | 11 | 0 | 10 |
| TRIP10 | SH3GL1 | 0.862843 | 11 | 0 | 10 |
| TRIP10 | PIM1 | 0.859084 | 11 | 0 | 11 |
| TRIP10 | MAPK3 | 0.856929 | 11 | 0 | 11 |
| TRIP10 | DUSP5 | 0.856922 | 11 | 0 | 11 |
| TRIP10 | PADI1 | 0.854308 | 9 | 0 | 9 |
| TRIP10 | CRISP3 | 0.850074 | 11 | 0 | 11 |
| TRIP10 | PRSS2 | 0.849889 | 8 | 0 | 8 |
| TRIP10 | SLURP1 | 0.849761 | 11 | 0 | 10 |
| TRIP10 | ARHGEF10L | 0.848177 | 11 | 0 | 11 |
| TRIP10 | IL18 | 0.844926 | 10 | 0 | 10 |
| TRIP10 | SNORA68 | 0.840815 | 4 | 0 | 4 |
| TRIP10 | MXD1 | 0.840158 | 11 | 0 | 10 |
| TRIP10 | MALL | 0.840125 | 11 | 0 | 11 |
| TRIP10 | CXCR2 | 0.839806 | 11 | 0 | 11 |
| TRIP10 | CYSRT1 | 0.839076 | 7 | 0 | 6 |
For details and further investigation, click here
