| Full name: EH domain containing 3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 2p23.1 | ||
| Entrez ID: 30845 | HGNC ID: HGNC:3244 | Ensembl Gene: ENSG00000013016 | OMIM ID: 605891 |
| Drug and gene relationship at DGIdb | |||
Expression of EHD3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EHD3 | 30845 | 218935_at | -2.2692 | 0.0842 | |
| GSE20347 | EHD3 | 30845 | 218935_at | -2.5275 | 0.0000 | |
| GSE23400 | EHD3 | 30845 | 218935_at | -2.1718 | 0.0000 | |
| GSE26886 | EHD3 | 30845 | 230740_at | -2.6551 | 0.0000 | |
| GSE29001 | EHD3 | 30845 | 218935_at | -2.5396 | 0.0000 | |
| GSE38129 | EHD3 | 30845 | 218935_at | -1.8631 | 0.0000 | |
| GSE45670 | EHD3 | 30845 | 230740_at | -1.1363 | 0.0035 | |
| GSE53622 | EHD3 | 30845 | 52066 | -2.4327 | 0.0000 | |
| GSE53624 | EHD3 | 30845 | 52066 | -2.7885 | 0.0000 | |
| GSE63941 | EHD3 | 30845 | 218935_at | -2.0130 | 0.0078 | |
| GSE77861 | EHD3 | 30845 | 218935_at | -2.0820 | 0.0003 | |
| GSE97050 | EHD3 | 30845 | A_23_P79251 | -1.3330 | 0.2193 | |
| SRP007169 | EHD3 | 30845 | RNAseq | -4.1721 | 0.0000 | |
| SRP008496 | EHD3 | 30845 | RNAseq | -3.8128 | 0.0000 | |
| SRP064894 | EHD3 | 30845 | RNAseq | -3.0192 | 0.0000 | |
| SRP133303 | EHD3 | 30845 | RNAseq | -2.4692 | 0.0000 | |
| SRP159526 | EHD3 | 30845 | RNAseq | -2.9764 | 0.0000 | |
| SRP193095 | EHD3 | 30845 | RNAseq | -2.2866 | 0.0000 | |
| SRP219564 | EHD3 | 30845 | RNAseq | -3.2496 | 0.0000 | |
| TCGA | EHD3 | 30845 | RNAseq | 0.1615 | 0.2023 |
Upregulated datasets: 0; Downregulated datasets: 17.
Survival by EHD3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of EHD3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EHD3 | 30845 | 10 | 1 | 19 | |
| GSE20123 | EHD3 | 30845 | 9 | 1 | 20 | |
| GSE43470 | EHD3 | 30845 | 2 | 1 | 40 | |
| GSE46452 | EHD3 | 30845 | 2 | 4 | 53 | |
| GSE47630 | EHD3 | 30845 | 8 | 0 | 32 | |
| GSE54993 | EHD3 | 30845 | 0 | 5 | 65 | |
| GSE54994 | EHD3 | 30845 | 10 | 0 | 43 | |
| GSE60625 | EHD3 | 30845 | 0 | 3 | 8 | |
| GSE74703 | EHD3 | 30845 | 2 | 0 | 34 | |
| GSE74704 | EHD3 | 30845 | 9 | 1 | 10 | |
| TCGA | EHD3 | 30845 | 36 | 2 | 58 |
Total number of gains: 88; Total number of losses: 18; Total Number of normals: 382.
Somatic mutations of EHD3:
Generating mutation plots.
Highly correlated genes for EHD3:
Showing top 20/1550 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EHD3 | CYSRT1 | 0.904197 | 6 | 0 | 6 |
| EHD3 | SLURP1 | 0.901869 | 10 | 0 | 10 |
| EHD3 | GYS2 | 0.900903 | 10 | 0 | 10 |
| EHD3 | SCNN1B | 0.896659 | 10 | 0 | 10 |
| EHD3 | RANBP9 | 0.884146 | 11 | 0 | 11 |
| EHD3 | SPINK7 | 0.88036 | 6 | 0 | 6 |
| EHD3 | VSIG10L | 0.878425 | 6 | 0 | 6 |
| EHD3 | CRISP3 | 0.876599 | 11 | 0 | 11 |
| EHD3 | CLIC3 | 0.873884 | 9 | 0 | 9 |
| EHD3 | SAMD5 | 0.870223 | 7 | 0 | 7 |
| EHD3 | ULK3 | 0.86915 | 7 | 0 | 7 |
| EHD3 | CXCR2 | 0.867682 | 11 | 0 | 11 |
| EHD3 | ANXA9 | 0.864728 | 11 | 0 | 11 |
| EHD3 | TTC9 | 0.86331 | 11 | 0 | 11 |
| EHD3 | IL36A | 0.859046 | 10 | 0 | 10 |
| EHD3 | A2ML1 | 0.858481 | 7 | 0 | 7 |
| EHD3 | EPGN | 0.853847 | 3 | 0 | 3 |
| EHD3 | VAT1 | 0.853117 | 12 | 0 | 12 |
| EHD3 | CLCA4 | 0.852754 | 10 | 0 | 10 |
| EHD3 | SH3GL1 | 0.852395 | 11 | 0 | 11 |
For details and further investigation, click here
