| Full name: ring finger protein 130 | Alias Symbol: GP|G1RZFP|GOLIATH | ||
| Type: protein-coding gene | Cytoband: 5q35.3 | ||
| Entrez ID: 55819 | HGNC ID: HGNC:18280 | Ensembl Gene: ENSG00000113269 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of RNF130:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RNF130 | 55819 | 217865_at | 0.2141 | 0.7743 | |
| GSE20347 | RNF130 | 55819 | 217865_at | 0.5528 | 0.0051 | |
| GSE23400 | RNF130 | 55819 | 217865_at | 0.2197 | 0.0266 | |
| GSE26886 | RNF130 | 55819 | 217865_at | 1.2984 | 0.0018 | |
| GSE29001 | RNF130 | 55819 | 217865_at | 0.5432 | 0.1154 | |
| GSE38129 | RNF130 | 55819 | 217865_at | 0.2942 | 0.2988 | |
| GSE45670 | RNF130 | 55819 | 217865_at | -0.4173 | 0.0877 | |
| GSE53622 | RNF130 | 55819 | 144266 | 0.2134 | 0.0620 | |
| GSE53624 | RNF130 | 55819 | 144266 | 0.5045 | 0.0000 | |
| GSE63941 | RNF130 | 55819 | 217865_at | -0.4075 | 0.4006 | |
| GSE77861 | RNF130 | 55819 | 217865_at | 1.1761 | 0.0033 | |
| GSE97050 | RNF130 | 55819 | A_23_P41734 | 0.0148 | 0.9737 | |
| SRP007169 | RNF130 | 55819 | RNAseq | 1.4912 | 0.0003 | |
| SRP008496 | RNF130 | 55819 | RNAseq | 1.1406 | 0.0000 | |
| SRP064894 | RNF130 | 55819 | RNAseq | 0.3580 | 0.2133 | |
| SRP133303 | RNF130 | 55819 | RNAseq | 0.6348 | 0.0000 | |
| SRP159526 | RNF130 | 55819 | RNAseq | 0.8351 | 0.0315 | |
| SRP193095 | RNF130 | 55819 | RNAseq | 0.6552 | 0.0002 | |
| TCGA | RNF130 | 55819 | RNAseq | -0.1316 | 0.0468 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by RNF130 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RNF130:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RNF130 | 55819 | 2 | 12 | 16 | |
| GSE20123 | RNF130 | 55819 | 2 | 12 | 16 | |
| GSE43470 | RNF130 | 55819 | 1 | 11 | 31 | |
| GSE46452 | RNF130 | 55819 | 0 | 27 | 32 | |
| GSE47630 | RNF130 | 55819 | 1 | 20 | 19 | |
| GSE54993 | RNF130 | 55819 | 10 | 2 | 58 | |
| GSE54994 | RNF130 | 55819 | 3 | 17 | 33 | |
| GSE60625 | RNF130 | 55819 | 1 | 0 | 10 | |
| GSE74703 | RNF130 | 55819 | 1 | 7 | 28 | |
| GSE74704 | RNF130 | 55819 | 1 | 6 | 13 | |
| TCGA | RNF130 | 55819 | 12 | 34 | 50 |
Total number of gains: 34; Total number of losses: 148; Total Number of normals: 306.
Somatic mutations of RNF130:
Generating mutation plots.
Highly correlated genes for RNF130:
Showing top 20/1843 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RNF130 | EFTUD2 | 0.820794 | 3 | 0 | 3 |
| RNF130 | ZNF251 | 0.810509 | 3 | 0 | 3 |
| RNF130 | ACBD6 | 0.792521 | 3 | 0 | 3 |
| RNF130 | KRTCAP2 | 0.792372 | 3 | 0 | 3 |
| RNF130 | LRRC14 | 0.790767 | 4 | 0 | 4 |
| RNF130 | GTPBP6 | 0.788608 | 3 | 0 | 3 |
| RNF130 | DUS3L | 0.782466 | 3 | 0 | 3 |
| RNF130 | CHD4 | 0.774207 | 4 | 0 | 4 |
| RNF130 | MED15 | 0.773291 | 3 | 0 | 3 |
| RNF130 | KIAA1257 | 0.772266 | 3 | 0 | 3 |
| RNF130 | VMA21 | 0.771655 | 3 | 0 | 3 |
| RNF130 | PPP1R35 | 0.767035 | 3 | 0 | 3 |
| RNF130 | AGK | 0.765243 | 3 | 0 | 3 |
| RNF130 | CHERP | 0.76511 | 3 | 0 | 3 |
| RNF130 | ZBED1 | 0.762597 | 4 | 0 | 3 |
| RNF130 | MRPL9 | 0.755034 | 3 | 0 | 3 |
| RNF130 | INTS3 | 0.75324 | 3 | 0 | 3 |
| RNF130 | HSD11B1 | 0.752756 | 6 | 0 | 6 |
| RNF130 | TOP1MT | 0.749913 | 3 | 0 | 3 |
| RNF130 | CRTC2 | 0.746623 | 3 | 0 | 3 |
For details and further investigation, click here
