| Full name: nitric oxide synthase interacting protein | Alias Symbol: CGI-25 | ||
| Type: protein-coding gene | Cytoband: 19q13.33 | ||
| Entrez ID: 51070 | HGNC ID: HGNC:17946 | Ensembl Gene: ENSG00000142546 | OMIM ID: 616759 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of NOSIP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NOSIP | 51070 | 217950_at | 0.4924 | 0.0981 | |
| GSE20347 | NOSIP | 51070 | 217950_at | 0.1435 | 0.3255 | |
| GSE23400 | NOSIP | 51070 | 217950_at | 0.1212 | 0.0230 | |
| GSE26886 | NOSIP | 51070 | 217950_at | 0.5656 | 0.0014 | |
| GSE29001 | NOSIP | 51070 | 217950_at | 0.2775 | 0.2768 | |
| GSE38129 | NOSIP | 51070 | 217950_at | 0.2402 | 0.0723 | |
| GSE45670 | NOSIP | 51070 | 217950_at | 0.3562 | 0.0172 | |
| GSE53622 | NOSIP | 51070 | 31800 | -0.2157 | 0.0236 | |
| GSE53624 | NOSIP | 51070 | 31800 | -0.0919 | 0.3745 | |
| GSE63941 | NOSIP | 51070 | 217950_at | 0.2424 | 0.5514 | |
| GSE77861 | NOSIP | 51070 | 217950_at | 0.2269 | 0.3648 | |
| GSE97050 | NOSIP | 51070 | A_24_P194017 | 0.2199 | 0.5004 | |
| SRP007169 | NOSIP | 51070 | RNAseq | -1.3100 | 0.0058 | |
| SRP008496 | NOSIP | 51070 | RNAseq | -0.6888 | 0.0630 | |
| SRP064894 | NOSIP | 51070 | RNAseq | 0.5046 | 0.2063 | |
| SRP133303 | NOSIP | 51070 | RNAseq | 0.0234 | 0.9036 | |
| SRP159526 | NOSIP | 51070 | RNAseq | 0.0806 | 0.7557 | |
| SRP193095 | NOSIP | 51070 | RNAseq | -0.1299 | 0.2436 | |
| SRP219564 | NOSIP | 51070 | RNAseq | -0.3285 | 0.2729 | |
| TCGA | NOSIP | 51070 | RNAseq | 0.0682 | 0.2367 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by NOSIP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NOSIP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NOSIP | 51070 | 4 | 4 | 22 | |
| GSE20123 | NOSIP | 51070 | 4 | 3 | 23 | |
| GSE43470 | NOSIP | 51070 | 4 | 11 | 28 | |
| GSE46452 | NOSIP | 51070 | 45 | 1 | 13 | |
| GSE47630 | NOSIP | 51070 | 10 | 6 | 24 | |
| GSE54993 | NOSIP | 51070 | 17 | 4 | 49 | |
| GSE54994 | NOSIP | 51070 | 4 | 14 | 35 | |
| GSE60625 | NOSIP | 51070 | 9 | 0 | 2 | |
| GSE74703 | NOSIP | 51070 | 4 | 7 | 25 | |
| GSE74704 | NOSIP | 51070 | 4 | 1 | 15 | |
| TCGA | NOSIP | 51070 | 14 | 19 | 63 |
Total number of gains: 119; Total number of losses: 70; Total Number of normals: 299.
Somatic mutations of NOSIP:
Generating mutation plots.
Highly correlated genes for NOSIP:
Showing top 20/792 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NOSIP | SAMD1 | 0.830024 | 3 | 0 | 3 |
| NOSIP | WDR75 | 0.815079 | 3 | 0 | 3 |
| NOSIP | DOK1 | 0.781425 | 3 | 0 | 3 |
| NOSIP | SNX6 | 0.777297 | 3 | 0 | 3 |
| NOSIP | FAM86C1 | 0.769908 | 3 | 0 | 3 |
| NOSIP | TP53I13 | 0.769743 | 3 | 0 | 3 |
| NOSIP | RRAS2 | 0.767506 | 3 | 0 | 3 |
| NOSIP | YY1 | 0.766836 | 3 | 0 | 3 |
| NOSIP | LRRC58 | 0.765987 | 3 | 0 | 3 |
| NOSIP | RNF139 | 0.760139 | 3 | 0 | 3 |
| NOSIP | PPIL4 | 0.755084 | 3 | 0 | 3 |
| NOSIP | LAP3 | 0.750876 | 3 | 0 | 3 |
| NOSIP | CXCL16 | 0.737976 | 3 | 0 | 3 |
| NOSIP | TMEM97 | 0.735238 | 3 | 0 | 3 |
| NOSIP | KRTCAP2 | 0.732501 | 4 | 0 | 4 |
| NOSIP | MCM6 | 0.728437 | 3 | 0 | 3 |
| NOSIP | SSBP4 | 0.726183 | 3 | 0 | 3 |
| NOSIP | CENPA | 0.725745 | 3 | 0 | 3 |
| NOSIP | SLC2A4RG | 0.725296 | 4 | 0 | 4 |
| NOSIP | KDM6B | 0.721609 | 3 | 0 | 3 |
For details and further investigation, click here
