| Full name: ring finger protein 166 | Alias Symbol: MGC2647|MGC14381 | ||
| Type: protein-coding gene | Cytoband: 16q24.2-q24.3 | ||
| Entrez ID: 115992 | HGNC ID: HGNC:28856 | Ensembl Gene: ENSG00000158717 | OMIM ID: 617178 |
| Drug and gene relationship at DGIdb | |||
Expression of RNF166:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RNF166 | 115992 | 227726_at | 0.6053 | 0.1823 | |
| GSE26886 | RNF166 | 115992 | 227726_at | 0.0182 | 0.9235 | |
| GSE45670 | RNF166 | 115992 | 227726_at | 0.0260 | 0.9036 | |
| GSE53622 | RNF166 | 115992 | 31899 | -0.1169 | 0.5794 | |
| GSE53624 | RNF166 | 115992 | 31899 | 0.2526 | 0.1637 | |
| GSE63941 | RNF166 | 115992 | 227726_at | 0.2402 | 0.6493 | |
| GSE77861 | RNF166 | 115992 | 227726_at | 0.3780 | 0.0523 | |
| GSE97050 | RNF166 | 115992 | A_23_P385500 | 0.1732 | 0.3590 | |
| SRP007169 | RNF166 | 115992 | RNAseq | 0.6771 | 0.1489 | |
| SRP008496 | RNF166 | 115992 | RNAseq | 0.9417 | 0.0203 | |
| SRP064894 | RNF166 | 115992 | RNAseq | 0.7081 | 0.0177 | |
| SRP133303 | RNF166 | 115992 | RNAseq | 0.1417 | 0.3835 | |
| SRP159526 | RNF166 | 115992 | RNAseq | 0.5230 | 0.0637 | |
| SRP193095 | RNF166 | 115992 | RNAseq | 0.6069 | 0.0003 | |
| SRP219564 | RNF166 | 115992 | RNAseq | 0.4212 | 0.3164 | |
| TCGA | RNF166 | 115992 | RNAseq | 0.0818 | 0.2568 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RNF166 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RNF166:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RNF166 | 115992 | 4 | 3 | 23 | |
| GSE20123 | RNF166 | 115992 | 4 | 3 | 23 | |
| GSE43470 | RNF166 | 115992 | 1 | 13 | 29 | |
| GSE46452 | RNF166 | 115992 | 38 | 1 | 20 | |
| GSE47630 | RNF166 | 115992 | 11 | 9 | 20 | |
| GSE54993 | RNF166 | 115992 | 3 | 4 | 63 | |
| GSE54994 | RNF166 | 115992 | 9 | 11 | 33 | |
| GSE60625 | RNF166 | 115992 | 4 | 0 | 7 | |
| GSE74703 | RNF166 | 115992 | 1 | 9 | 26 | |
| GSE74704 | RNF166 | 115992 | 3 | 2 | 15 | |
| TCGA | RNF166 | 115992 | 28 | 15 | 53 |
Total number of gains: 106; Total number of losses: 70; Total Number of normals: 312.
Somatic mutations of RNF166:
Generating mutation plots.
Highly correlated genes for RNF166:
Showing top 20/411 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RNF166 | ZXDC | 0.808769 | 3 | 0 | 3 |
| RNF166 | QSOX2 | 0.802153 | 3 | 0 | 3 |
| RNF166 | WDR81 | 0.788996 | 3 | 0 | 3 |
| RNF166 | SEC61A1 | 0.771654 | 3 | 0 | 3 |
| RNF166 | MYNN | 0.766424 | 3 | 0 | 3 |
| RNF166 | LYRM4 | 0.762118 | 3 | 0 | 3 |
| RNF166 | RCN1 | 0.761607 | 3 | 0 | 3 |
| RNF166 | RIOK1 | 0.750134 | 3 | 0 | 3 |
| RNF166 | LIN9 | 0.743798 | 3 | 0 | 3 |
| RNF166 | SOX4 | 0.742816 | 3 | 0 | 3 |
| RNF166 | EIF4G1 | 0.741417 | 3 | 0 | 3 |
| RNF166 | TAP1 | 0.739951 | 3 | 0 | 3 |
| RNF166 | OSGEPL1 | 0.731406 | 3 | 0 | 3 |
| RNF166 | PLEKHA3 | 0.731091 | 4 | 0 | 4 |
| RNF166 | ARHGAP18 | 0.729023 | 4 | 0 | 4 |
| RNF166 | NAA15 | 0.724322 | 3 | 0 | 3 |
| RNF166 | PLXNA1 | 0.723187 | 3 | 0 | 3 |
| RNF166 | ASXL1 | 0.721691 | 3 | 0 | 3 |
| RNF166 | ZNF7 | 0.720413 | 3 | 0 | 3 |
| RNF166 | SENP3 | 0.720175 | 3 | 0 | 3 |
For details and further investigation, click here
