| Full name: solute carrier family 15 member 3 | Alias Symbol: PHT2|hPTR3 | ||
| Type: protein-coding gene | Cytoband: 11q12.2 | ||
| Entrez ID: 51296 | HGNC ID: HGNC:18068 | Ensembl Gene: ENSG00000110446 | OMIM ID: 610408 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC15A3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC15A3 | 51296 | 219593_at | 0.0395 | 0.9619 | |
| GSE20347 | SLC15A3 | 51296 | 219593_at | 0.1308 | 0.4642 | |
| GSE23400 | SLC15A3 | 51296 | 219593_at | 0.1051 | 0.2109 | |
| GSE26886 | SLC15A3 | 51296 | 219593_at | 0.1956 | 0.5269 | |
| GSE29001 | SLC15A3 | 51296 | 219593_at | 0.2683 | 0.1701 | |
| GSE38129 | SLC15A3 | 51296 | 219593_at | 0.0836 | 0.6193 | |
| GSE45670 | SLC15A3 | 51296 | 219593_at | 0.3926 | 0.0894 | |
| GSE53622 | SLC15A3 | 51296 | 79012 | 0.8209 | 0.0000 | |
| GSE53624 | SLC15A3 | 51296 | 79012 | 1.1302 | 0.0000 | |
| GSE63941 | SLC15A3 | 51296 | 219593_at | -0.3070 | 0.4395 | |
| GSE77861 | SLC15A3 | 51296 | 219593_at | 0.0151 | 0.9259 | |
| GSE97050 | SLC15A3 | 51296 | A_23_P75786 | 0.5843 | 0.2185 | |
| SRP007169 | SLC15A3 | 51296 | RNAseq | 1.9363 | 0.0112 | |
| SRP008496 | SLC15A3 | 51296 | RNAseq | 1.3559 | 0.0141 | |
| SRP064894 | SLC15A3 | 51296 | RNAseq | 1.6625 | 0.0000 | |
| SRP133303 | SLC15A3 | 51296 | RNAseq | 0.9833 | 0.0034 | |
| SRP159526 | SLC15A3 | 51296 | RNAseq | 0.2304 | 0.6680 | |
| SRP193095 | SLC15A3 | 51296 | RNAseq | 1.1709 | 0.0000 | |
| SRP219564 | SLC15A3 | 51296 | RNAseq | 1.6626 | 0.0391 | |
| TCGA | SLC15A3 | 51296 | RNAseq | 0.2406 | 0.0529 |
Upregulated datasets: 6; Downregulated datasets: 0.
Survival by SLC15A3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC15A3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC15A3 | 51296 | 2 | 5 | 23 | |
| GSE20123 | SLC15A3 | 51296 | 2 | 5 | 23 | |
| GSE43470 | SLC15A3 | 51296 | 2 | 6 | 35 | |
| GSE46452 | SLC15A3 | 51296 | 8 | 4 | 47 | |
| GSE47630 | SLC15A3 | 51296 | 3 | 8 | 29 | |
| GSE54993 | SLC15A3 | 51296 | 3 | 0 | 67 | |
| GSE54994 | SLC15A3 | 51296 | 5 | 5 | 43 | |
| GSE60625 | SLC15A3 | 51296 | 0 | 3 | 8 | |
| GSE74703 | SLC15A3 | 51296 | 2 | 3 | 31 | |
| GSE74704 | SLC15A3 | 51296 | 2 | 3 | 15 | |
| TCGA | SLC15A3 | 51296 | 15 | 10 | 71 |
Total number of gains: 44; Total number of losses: 52; Total Number of normals: 392.
Somatic mutations of SLC15A3:
Generating mutation plots.
Highly correlated genes for SLC15A3:
Showing top 20/585 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC15A3 | FCGR3A | 0.786479 | 3 | 0 | 3 |
| SLC15A3 | ANGPTL6 | 0.78096 | 3 | 0 | 3 |
| SLC15A3 | SLC29A3 | 0.770579 | 3 | 0 | 3 |
| SLC15A3 | CACNA2D4 | 0.757585 | 3 | 0 | 3 |
| SLC15A3 | LRRC8C | 0.74568 | 3 | 0 | 3 |
| SLC15A3 | C19orf38 | 0.734516 | 3 | 0 | 3 |
| SLC15A3 | SUSD1 | 0.726689 | 3 | 0 | 3 |
| SLC15A3 | RNF34 | 0.725472 | 3 | 0 | 3 |
| SLC15A3 | SUCNR1 | 0.724962 | 4 | 0 | 4 |
| SLC15A3 | TAGAP | 0.719854 | 4 | 0 | 4 |
| SLC15A3 | KTI12 | 0.717241 | 3 | 0 | 3 |
| SLC15A3 | RASSF4 | 0.716869 | 5 | 0 | 4 |
| SLC15A3 | PRPS1 | 0.708995 | 3 | 0 | 3 |
| SLC15A3 | CERKL | 0.707172 | 3 | 0 | 3 |
| SLC15A3 | SPI1 | 0.703997 | 6 | 0 | 4 |
| SLC15A3 | ST3GAL2 | 0.698746 | 3 | 0 | 3 |
| SLC15A3 | PIK3R5 | 0.69751 | 4 | 0 | 4 |
| SLC15A3 | ABCF2 | 0.697357 | 3 | 0 | 3 |
| SLC15A3 | EPSTI1 | 0.697302 | 8 | 0 | 7 |
| SLC15A3 | HSD3B7 | 0.690266 | 4 | 0 | 4 |
For details and further investigation, click here
