| Full name: lactate dehydrogenase C | Alias Symbol: CT32 | ||
| Type: protein-coding gene | Cytoband: 11p15.1 | ||
| Entrez ID: 3948 | HGNC ID: HGNC:6544 | Ensembl Gene: ENSG00000166796 | OMIM ID: 150150 |
| Drug and gene relationship at DGIdb | |||
Expression of LDHC:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LDHC | 3948 | 207022_s_at | 0.1768 | 0.6051 | |
| GSE20347 | LDHC | 3948 | 207022_s_at | -0.0606 | 0.2937 | |
| GSE23400 | LDHC | 3948 | 207022_s_at | 0.0229 | 0.6380 | |
| GSE26886 | LDHC | 3948 | 207022_s_at | -0.3077 | 0.1039 | |
| GSE29001 | LDHC | 3948 | 207022_s_at | -0.0498 | 0.7524 | |
| GSE38129 | LDHC | 3948 | 207022_s_at | 0.0404 | 0.6125 | |
| GSE45670 | LDHC | 3948 | 207022_s_at | 0.1979 | 0.1157 | |
| GSE53622 | LDHC | 3948 | 88817 | 0.2690 | 0.0002 | |
| GSE53624 | LDHC | 3948 | 88817 | 0.6066 | 0.0000 | |
| GSE63941 | LDHC | 3948 | 207022_s_at | 0.0645 | 0.8461 | |
| GSE77861 | LDHC | 3948 | 207022_s_at | -0.0017 | 0.9927 | |
| GSE97050 | LDHC | 3948 | A_23_P53039 | -0.0066 | 0.9813 | |
| SRP133303 | LDHC | 3948 | RNAseq | 0.1878 | 0.4444 | |
| TCGA | LDHC | 3948 | RNAseq | 0.5717 | 0.6095 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by LDHC expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LDHC:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LDHC | 3948 | 0 | 10 | 20 | |
| GSE20123 | LDHC | 3948 | 0 | 10 | 20 | |
| GSE43470 | LDHC | 3948 | 1 | 5 | 37 | |
| GSE46452 | LDHC | 3948 | 7 | 5 | 47 | |
| GSE47630 | LDHC | 3948 | 3 | 10 | 27 | |
| GSE54993 | LDHC | 3948 | 3 | 0 | 67 | |
| GSE54994 | LDHC | 3948 | 2 | 13 | 38 | |
| GSE60625 | LDHC | 3948 | 0 | 0 | 11 | |
| GSE74703 | LDHC | 3948 | 1 | 3 | 32 | |
| GSE74704 | LDHC | 3948 | 0 | 9 | 11 | |
| TCGA | LDHC | 3948 | 11 | 29 | 56 |
Total number of gains: 28; Total number of losses: 94; Total Number of normals: 366.
Somatic mutations of LDHC:
Generating mutation plots.
Highly correlated genes for LDHC:
Showing top 20/97 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LDHC | GPR150 | 0.850059 | 3 | 0 | 3 |
| LDHC | FFAR2 | 0.764362 | 3 | 0 | 3 |
| LDHC | SLC22A25 | 0.751748 | 3 | 0 | 3 |
| LDHC | SCARF2 | 0.746617 | 3 | 0 | 3 |
| LDHC | POU1F1 | 0.710129 | 3 | 0 | 3 |
| LDHC | C22orf23 | 0.690863 | 3 | 0 | 3 |
| LDHC | APOL4 | 0.686713 | 3 | 0 | 3 |
| LDHC | ADAMTS7 | 0.679102 | 5 | 0 | 4 |
| LDHC | DHRS7C | 0.671384 | 3 | 0 | 3 |
| LDHC | RP1L1 | 0.66828 | 3 | 0 | 3 |
| LDHC | SNAI2 | 0.668071 | 3 | 0 | 3 |
| LDHC | BCL6B | 0.661153 | 3 | 0 | 3 |
| LDHC | LAMA3 | 0.655878 | 4 | 0 | 4 |
| LDHC | UQCRC1 | 0.649077 | 3 | 0 | 3 |
| LDHC | MUC8 | 0.642833 | 3 | 0 | 3 |
| LDHC | OR7A17 | 0.638494 | 5 | 0 | 4 |
| LDHC | PINX1 | 0.637245 | 3 | 0 | 3 |
| LDHC | EGR4 | 0.63604 | 3 | 0 | 3 |
| LDHC | CLCN1 | 0.634876 | 3 | 0 | 3 |
| LDHC | NPR2 | 0.634876 | 4 | 0 | 3 |
For details and further investigation, click here
