C12orf43

 

Full name: chromosome 12 open reading frame 43 Alias Symbol: FLJ12448|Custos
Type: protein-coding gene Cytoband: 12q24.31
Entrez ID: 64897 HGNC ID: HGNC:25719 Ensembl Gene: ENSG00000157895 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of C12orf43:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 C12orf43 64897 219022_at 0.3925 0.2594
GSE20347 C12orf43 64897 219022_at 0.4988 0.0007
GSE23400 C12orf43 64897 219022_at 0.1911 0.0000
GSE26886 C12orf43 64897 219022_at 0.5839 0.0030
GSE29001 C12orf43 64897 219022_at 0.6984 0.0016
GSE38129 C12orf43 64897 219022_at 0.3510 0.0079
GSE45670 C12orf43 64897 219022_at 0.3130 0.0088
GSE53622 C12orf43 64897 22647 0.5512 0.0000
GSE53624 C12orf43 64897 22647 0.6809 0.0000
GSE63941 C12orf43 64897 219022_at 0.6150 0.0457
GSE77861 C12orf43 64897 219022_at 0.1703 0.3460
GSE97050 C12orf43 64897 A_23_P151179 0.0094 0.9729
SRP007169 C12orf43 64897 RNAseq 1.8380 0.0159
SRP064894 C12orf43 64897 RNAseq 0.4546 0.0351
SRP133303 C12orf43 64897 RNAseq 0.2467 0.0451
SRP159526 C12orf43 64897 RNAseq 0.3750 0.1288
SRP193095 C12orf43 64897 RNAseq 0.2565 0.0004
SRP219564 C12orf43 64897 RNAseq -0.0519 0.8868
TCGA C12orf43 64897 RNAseq 0.0124 0.8433

Upregulated datasets: 1; Downregulated datasets: 0.  

 

Survival by C12orf43 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of C12orf43:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 C12orf43 64897 6 2 22
GSE20123 C12orf43 64897 6 2 22
GSE43470 C12orf43 64897 2 2 39
GSE46452 C12orf43 64897 9 1 49
GSE47630 C12orf43 64897 9 3 28
GSE54993 C12orf43 64897 0 5 65
GSE54994 C12orf43 64897 6 7 40
GSE60625 C12orf43 64897 0 0 11
GSE74703 C12orf43 64897 2 1 33
GSE74704 C12orf43 64897 3 2 15
TCGA C12orf43 64897 21 11 64

Total number of gains: 64; Total number of losses: 36; Total Number of normals: 388.  

 

Somatic mutations of C12orf43:

 

Generating mutation plots.

 

Highly correlated genes for C12orf43:

 

Showing top 20/1219 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
C12orf43ZXDA0.799655303
C12orf43NNT0.758161303
C12orf43C3orf330.740822404
C12orf43ZBTB340.739948303
C12orf43GNG100.736857303
C12orf43G2E30.735703505
C12orf43TXNDC160.733979303
C12orf43SWT10.723372303
C12orf43FCGR3A0.719482303
C12orf43MFN20.717701303
C12orf43SRSF60.716189303
C12orf43SPNS10.713677404
C12orf43RPAIN0.711119303
C12orf43USP340.707237303
C12orf43ZNF6440.704159303
C12orf43RNASEH2B0.703224303
C12orf43HSPA50.702846303
C12orf43LGALS80.69502303
C12orf43RIMKLA0.694677303
C12orf43CD2BP20.683367303

For details and further investigation, click here