HS3ST3B1

 

Full name: heparan sulfate-glucosamine 3-sulfotransferase 3B1 Alias Symbol: 3OST3B1|30ST3B1
Type: protein-coding gene Cytoband: 17p12
Entrez ID: 9953 HGNC ID: HGNC:5198 Ensembl Gene: ENSG00000125430 OMIM ID: 604058
Drug and gene relationship at DGIdb

 

Expression of HS3ST3B1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 HS3ST3B1 9953 227361_at 0.5030 0.5926
GSE20347 HS3ST3B1 9953 221062_at -0.0655 0.2306
GSE23400 HS3ST3B1 9953 221062_at -0.0234 0.3017
GSE26886 HS3ST3B1 9953 227361_at -0.0946 0.8343
GSE29001 HS3ST3B1 9953 221062_at -0.0266 0.8565
GSE38129 HS3ST3B1 9953 221062_at -0.0918 0.0408
GSE45670 HS3ST3B1 9953 227361_at 0.5277 0.0720
GSE53622 HS3ST3B1 9953 50571 0.3926 0.0040
GSE53624 HS3ST3B1 9953 82306 -0.2417 0.1182
GSE63941 HS3ST3B1 9953 227361_at -2.7308 0.1118
GSE77861 HS3ST3B1 9953 1561908_a_at -0.1274 0.1549
GSE97050 HS3ST3B1 9953 A_23_P77918 0.8528 0.1791
SRP007169 HS3ST3B1 9953 RNAseq -0.7650 0.1386
SRP008496 HS3ST3B1 9953 RNAseq 0.1785 0.6774
SRP064894 HS3ST3B1 9953 RNAseq 0.1848 0.5374
SRP133303 HS3ST3B1 9953 RNAseq 0.1163 0.5891
SRP159526 HS3ST3B1 9953 RNAseq -0.4003 0.3269
SRP193095 HS3ST3B1 9953 RNAseq 0.4062 0.0681
SRP219564 HS3ST3B1 9953 RNAseq 1.2855 0.0258
TCGA HS3ST3B1 9953 RNAseq 0.0930 0.6438

Upregulated datasets: 1; Downregulated datasets: 0.  


 

Survival by HS3ST3B1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of HS3ST3B1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 HS3ST3B1 9953 3 3 24
GSE20123 HS3ST3B1 9953 3 3 24
GSE43470 HS3ST3B1 9953 2 5 36
GSE46452 HS3ST3B1 9953 34 1 24
GSE47630 HS3ST3B1 9953 7 1 32
GSE54993 HS3ST3B1 9953 3 2 65
GSE54994 HS3ST3B1 9953 6 6 41
GSE60625 HS3ST3B1 9953 4 0 7
GSE74703 HS3ST3B1 9953 2 4 30
GSE74704 HS3ST3B1 9953 2 2 16
TCGA HS3ST3B1 9953 18 22 56

Total number of gains: 84; Total number of losses: 49; Total Number of normals: 355.  


 

Somatic mutations of HS3ST3B1:

 

Generating mutation plots.

 

Highly correlated genes for HS3ST3B1:

 

Showing top 20/77 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
HS3ST3B1IRX30.663311403
HS3ST3B1RPH3AL0.662606303
HS3ST3B1CHRNB30.657744303
HS3ST3B1SCN11A0.647989303
HS3ST3B1MANF0.644673403
HS3ST3B1ACAD90.634324303
HS3ST3B1CCL230.631944303
HS3ST3B1NEUROD20.621642303
HS3ST3B1FDXACB10.620789303
HS3ST3B1LZTS10.617277403
HS3ST3B1CHRNB40.613442303
HS3ST3B1HTATIP20.609308403
HS3ST3B1CALR0.605448403
HS3ST3B1GMFG0.604169303
HS3ST3B1TP530.600137403
HS3ST3B1MINK10.596035303
HS3ST3B1TTLL40.594769303
HS3ST3B1GRIN2B0.592359403
HS3ST3B1MYSM10.592348303
HS3ST3B1AMPH0.591674303

For details and further investigation, click here