| Full name: FERM domain containing 8 | Alias Symbol: FLJ90369|FKSG44|iTAP | ||
| Type: protein-coding gene | Cytoband: 11q13.1 | ||
| Entrez ID: 83786 | HGNC ID: HGNC:25462 | Ensembl Gene: ENSG00000126391 | OMIM ID: 618337 |
| Drug and gene relationship at DGIdb | |||
Expression of FRMD8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FRMD8 | 83786 | 227964_at | 0.5940 | 0.4470 | |
| GSE20347 | FRMD8 | 83786 | 210043_at | -0.1222 | 0.1419 | |
| GSE23400 | FRMD8 | 83786 | 210043_at | -0.0344 | 0.3352 | |
| GSE26886 | FRMD8 | 83786 | 227964_at | -0.4680 | 0.0645 | |
| GSE29001 | FRMD8 | 83786 | 210043_at | -0.2494 | 0.1606 | |
| GSE38129 | FRMD8 | 83786 | 210043_at | -0.0864 | 0.2514 | |
| GSE45670 | FRMD8 | 83786 | 227964_at | 0.6811 | 0.0000 | |
| GSE53622 | FRMD8 | 83786 | 70844 | 0.0369 | 0.7351 | |
| GSE53624 | FRMD8 | 83786 | 70844 | 0.1873 | 0.0068 | |
| GSE63941 | FRMD8 | 83786 | 227964_at | 0.1117 | 0.8493 | |
| GSE77861 | FRMD8 | 83786 | 227964_at | 0.5479 | 0.0812 | |
| GSE97050 | FRMD8 | 83786 | A_24_P67988 | 0.0489 | 0.9413 | |
| SRP007169 | FRMD8 | 83786 | RNAseq | -0.4252 | 0.3416 | |
| SRP008496 | FRMD8 | 83786 | RNAseq | -0.2867 | 0.2545 | |
| SRP064894 | FRMD8 | 83786 | RNAseq | -0.1858 | 0.3087 | |
| SRP133303 | FRMD8 | 83786 | RNAseq | 0.2791 | 0.1283 | |
| SRP159526 | FRMD8 | 83786 | RNAseq | 0.0070 | 0.9790 | |
| SRP193095 | FRMD8 | 83786 | RNAseq | 0.0822 | 0.5739 | |
| SRP219564 | FRMD8 | 83786 | RNAseq | -0.3616 | 0.5002 | |
| TCGA | FRMD8 | 83786 | RNAseq | 0.2574 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by FRMD8 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FRMD8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FRMD8 | 83786 | 8 | 5 | 17 | |
| GSE20123 | FRMD8 | 83786 | 8 | 5 | 17 | |
| GSE43470 | FRMD8 | 83786 | 4 | 1 | 38 | |
| GSE46452 | FRMD8 | 83786 | 11 | 3 | 45 | |
| GSE47630 | FRMD8 | 83786 | 7 | 5 | 28 | |
| GSE54993 | FRMD8 | 83786 | 3 | 0 | 67 | |
| GSE54994 | FRMD8 | 83786 | 7 | 5 | 41 | |
| GSE60625 | FRMD8 | 83786 | 0 | 3 | 8 | |
| GSE74703 | FRMD8 | 83786 | 3 | 0 | 33 | |
| GSE74704 | FRMD8 | 83786 | 6 | 3 | 11 | |
| TCGA | FRMD8 | 83786 | 23 | 7 | 66 |
Total number of gains: 80; Total number of losses: 37; Total Number of normals: 371.
Somatic mutations of FRMD8:
Generating mutation plots.
Highly correlated genes for FRMD8:
Showing top 20/328 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FRMD8 | NAT1 | 0.828923 | 3 | 0 | 3 |
| FRMD8 | ADCY7 | 0.771094 | 3 | 0 | 3 |
| FRMD8 | NPFFR1 | 0.770628 | 3 | 0 | 3 |
| FRMD8 | TFAP4 | 0.761843 | 3 | 0 | 3 |
| FRMD8 | JKAMP | 0.757256 | 3 | 0 | 3 |
| FRMD8 | SP140L | 0.751323 | 4 | 0 | 4 |
| FRMD8 | PARP14 | 0.750402 | 3 | 0 | 3 |
| FRMD8 | TRIM59 | 0.735169 | 3 | 0 | 3 |
| FRMD8 | UHMK1 | 0.729559 | 4 | 0 | 4 |
| FRMD8 | TNFSF8 | 0.726844 | 4 | 0 | 4 |
| FRMD8 | C1orf131 | 0.722381 | 4 | 0 | 4 |
| FRMD8 | ARHGAP1 | 0.719201 | 3 | 0 | 3 |
| FRMD8 | UTY | 0.71898 | 3 | 0 | 3 |
| FRMD8 | STAT2 | 0.715426 | 5 | 0 | 5 |
| FRMD8 | PPP4R2 | 0.712945 | 3 | 0 | 3 |
| FRMD8 | UBR4 | 0.711934 | 3 | 0 | 3 |
| FRMD8 | BAIAP2L1 | 0.70443 | 3 | 0 | 3 |
| FRMD8 | TMEM41A | 0.703407 | 3 | 0 | 3 |
| FRMD8 | LMF2 | 0.703116 | 3 | 0 | 3 |
| FRMD8 | PPIL1 | 0.696861 | 4 | 0 | 4 |
For details and further investigation, click here
