| Full name: NEDD4 binding protein 3 | Alias Symbol: LZTS4 | ||
| Type: protein-coding gene | Cytoband: 5q35.3 | ||
| Entrez ID: 23138 | HGNC ID: HGNC:29852 | Ensembl Gene: ENSG00000145911 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of N4BP3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | N4BP3 | 23138 | 214775_at | -0.2832 | 0.3872 | |
| GSE20347 | N4BP3 | 23138 | 214775_at | -0.3830 | 0.0001 | |
| GSE23400 | N4BP3 | 23138 | 214775_at | -0.6664 | 0.0000 | |
| GSE26886 | N4BP3 | 23138 | 214775_at | -0.7627 | 0.0001 | |
| GSE29001 | N4BP3 | 23138 | 214775_at | -0.5135 | 0.0055 | |
| GSE38129 | N4BP3 | 23138 | 214775_at | -0.4315 | 0.0000 | |
| GSE45670 | N4BP3 | 23138 | 214775_at | -0.4525 | 0.0157 | |
| GSE53622 | N4BP3 | 23138 | 8242 | -2.5978 | 0.0000 | |
| GSE53624 | N4BP3 | 23138 | 8242 | -2.6729 | 0.0000 | |
| GSE63941 | N4BP3 | 23138 | 214775_at | 0.0215 | 0.9314 | |
| GSE77861 | N4BP3 | 23138 | 214775_at | -0.3630 | 0.0094 | |
| GSE97050 | N4BP3 | 23138 | A_24_P140666 | -0.8942 | 0.1379 | |
| SRP007169 | N4BP3 | 23138 | RNAseq | -3.9304 | 0.0000 | |
| SRP008496 | N4BP3 | 23138 | RNAseq | -4.0105 | 0.0000 | |
| SRP064894 | N4BP3 | 23138 | RNAseq | -2.0685 | 0.0000 | |
| SRP133303 | N4BP3 | 23138 | RNAseq | -2.5855 | 0.0000 | |
| SRP159526 | N4BP3 | 23138 | RNAseq | -2.0263 | 0.0004 | |
| SRP193095 | N4BP3 | 23138 | RNAseq | -1.9540 | 0.0000 | |
| SRP219564 | N4BP3 | 23138 | RNAseq | -2.1111 | 0.0036 | |
| TCGA | N4BP3 | 23138 | RNAseq | -0.3271 | 0.0038 |
Upregulated datasets: 0; Downregulated datasets: 9.
Survival by N4BP3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of N4BP3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | N4BP3 | 23138 | 2 | 13 | 15 | |
| GSE20123 | N4BP3 | 23138 | 2 | 13 | 15 | |
| GSE43470 | N4BP3 | 23138 | 1 | 11 | 31 | |
| GSE46452 | N4BP3 | 23138 | 0 | 27 | 32 | |
| GSE47630 | N4BP3 | 23138 | 1 | 20 | 19 | |
| GSE54993 | N4BP3 | 23138 | 10 | 2 | 58 | |
| GSE54994 | N4BP3 | 23138 | 2 | 17 | 34 | |
| GSE60625 | N4BP3 | 23138 | 1 | 0 | 10 | |
| GSE74703 | N4BP3 | 23138 | 1 | 7 | 28 | |
| GSE74704 | N4BP3 | 23138 | 1 | 6 | 13 | |
| TCGA | N4BP3 | 23138 | 8 | 34 | 54 |
Total number of gains: 29; Total number of losses: 150; Total Number of normals: 309.
Somatic mutations of N4BP3:
Generating mutation plots.
Highly correlated genes for N4BP3:
Showing top 20/1658 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| N4BP3 | CA13 | 0.801915 | 3 | 0 | 3 |
| N4BP3 | FAM3D | 0.786744 | 7 | 0 | 7 |
| N4BP3 | ZFAND2B | 0.785588 | 7 | 0 | 7 |
| N4BP3 | PLEKHA7 | 0.783836 | 7 | 0 | 7 |
| N4BP3 | RMND5B | 0.78257 | 12 | 0 | 11 |
| N4BP3 | TRIP10 | 0.7792 | 11 | 0 | 11 |
| N4BP3 | ANXA9 | 0.777245 | 11 | 0 | 11 |
| N4BP3 | C18orf25 | 0.775466 | 11 | 0 | 10 |
| N4BP3 | SASH1 | 0.773764 | 11 | 0 | 11 |
| N4BP3 | PADI1 | 0.765084 | 8 | 0 | 8 |
| N4BP3 | EPGN | 0.764952 | 3 | 0 | 3 |
| N4BP3 | HPGD | 0.764704 | 11 | 0 | 11 |
| N4BP3 | ARHGEF10L | 0.764537 | 11 | 0 | 11 |
| N4BP3 | CASC3 | 0.763327 | 3 | 0 | 3 |
| N4BP3 | EPS8L1 | 0.763124 | 11 | 0 | 11 |
| N4BP3 | C5orf66-AS1 | 0.762792 | 6 | 0 | 6 |
| N4BP3 | SPATA19 | 0.758706 | 3 | 0 | 3 |
| N4BP3 | FNDC4 | 0.756689 | 10 | 0 | 10 |
| N4BP3 | EPS8L2 | 0.755802 | 10 | 0 | 10 |
| N4BP3 | FUT3 | 0.755413 | 11 | 0 | 11 |
For details and further investigation, click here
