| Full name: ribosomal protein S3A | Alias Symbol: S3A | ||
| Type: protein-coding gene | Cytoband: 4q31.3 | ||
| Entrez ID: 6189 | HGNC ID: HGNC:10421 | Ensembl Gene: ENSG00000145425 | OMIM ID: 180478 |
| Drug and gene relationship at DGIdb | |||
Expression of RPS3A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | RPS3A | 6189 | 66424 | -0.4900 | 0.0000 | |
| GSE53624 | RPS3A | 6189 | 66424 | -0.3550 | 0.0000 | |
| GSE97050 | RPS3A | 6189 | A_23_P144497 | -0.5815 | 0.1855 | |
| SRP007169 | RPS3A | 6189 | RNAseq | -1.1321 | 0.0074 | |
| SRP008496 | RPS3A | 6189 | RNAseq | -1.0638 | 0.0000 | |
| SRP064894 | RPS3A | 6189 | RNAseq | -0.6663 | 0.0360 | |
| SRP133303 | RPS3A | 6189 | RNAseq | -0.5029 | 0.0023 | |
| SRP159526 | RPS3A | 6189 | RNAseq | -0.8058 | 0.0014 | |
| SRP193095 | RPS3A | 6189 | RNAseq | -1.3296 | 0.0000 | |
| SRP219564 | RPS3A | 6189 | RNAseq | -0.9061 | 0.0003 | |
| TCGA | RPS3A | 6189 | RNAseq | -0.1119 | 0.0260 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by RPS3A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RPS3A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RPS3A | 6189 | 1 | 13 | 16 | |
| GSE20123 | RPS3A | 6189 | 1 | 13 | 16 | |
| GSE43470 | RPS3A | 6189 | 0 | 14 | 29 | |
| GSE46452 | RPS3A | 6189 | 1 | 36 | 22 | |
| GSE47630 | RPS3A | 6189 | 0 | 23 | 17 | |
| GSE54993 | RPS3A | 6189 | 10 | 0 | 60 | |
| GSE54994 | RPS3A | 6189 | 1 | 12 | 40 | |
| GSE60625 | RPS3A | 6189 | 0 | 1 | 10 | |
| GSE74703 | RPS3A | 6189 | 0 | 12 | 24 | |
| GSE74704 | RPS3A | 6189 | 0 | 7 | 13 | |
| TCGA | RPS3A | 6189 | 10 | 35 | 51 |
Total number of gains: 24; Total number of losses: 166; Total Number of normals: 298.
Somatic mutations of RPS3A:
Generating mutation plots.
Highly correlated genes for RPS3A:
Showing top 20/21 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RPS3A | RPL29 | 0.668173 | 3 | 0 | 3 |
| RPS3A | RPLP0 | 0.666387 | 3 | 0 | 3 |
| RPS3A | RPL3 | 0.665361 | 3 | 0 | 3 |
| RPS3A | RPL11 | 0.658597 | 3 | 0 | 3 |
| RPS3A | RPL15 | 0.641262 | 4 | 0 | 3 |
| RPS3A | RPL10A | 0.619988 | 4 | 0 | 3 |
| RPS3A | AAMP | 0.609848 | 3 | 0 | 3 |
| RPS3A | RPL6 | 0.575972 | 4 | 0 | 3 |
| RPS3A | RPL5 | 0.574102 | 3 | 0 | 3 |
| RPS3A | RPL18A | 0.570528 | 4 | 0 | 3 |
| RPS3A | LRBA | 0.566375 | 3 | 0 | 3 |
| RPS3A | RPL22 | 0.563692 | 4 | 0 | 3 |
| RPS3A | RPS14 | 0.559146 | 4 | 0 | 3 |
| RPS3A | CIRBP | 0.555215 | 3 | 0 | 3 |
| RPS3A | EEF1A1 | 0.542746 | 4 | 0 | 3 |
| RPS3A | LANCL1 | 0.535557 | 4 | 0 | 3 |
| RPS3A | RPS24 | 0.53531 | 4 | 0 | 3 |
| RPS3A | UFSP2 | 0.530909 | 3 | 0 | 3 |
| RPS3A | ACADM | 0.525848 | 4 | 0 | 3 |
| RPS3A | HIGD1A | 0.51848 | 4 | 0 | 3 |
For details and further investigation, click here
