| Full name: ribosomal protein lateral stalk subunit P2 | Alias Symbol: P2|RPP2|MGC71408|LP2 | ||
| Type: protein-coding gene | Cytoband: 11p15.5 | ||
| Entrez ID: 6181 | HGNC ID: HGNC:10377 | Ensembl Gene: ENSG00000177600 | OMIM ID: 180530 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of RPLP2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RPLP2 | 6181 | 200908_s_at | -0.0212 | 0.9537 | |
| GSE20347 | RPLP2 | 6181 | 200908_s_at | -0.1575 | 0.1014 | |
| GSE23400 | RPLP2 | 6181 | 200908_s_at | -0.0771 | 0.0605 | |
| GSE26886 | RPLP2 | 6181 | 200908_s_at | 0.2442 | 0.5729 | |
| GSE29001 | RPLP2 | 6181 | 200908_s_at | -0.5580 | 0.0746 | |
| GSE38129 | RPLP2 | 6181 | 200908_s_at | -0.1197 | 0.5497 | |
| GSE45670 | RPLP2 | 6181 | 200908_s_at | 0.1291 | 0.2194 | |
| GSE63941 | RPLP2 | 6181 | 200908_s_at | 0.3397 | 0.0966 | |
| GSE77861 | RPLP2 | 6181 | 217670_at | -0.0236 | 0.7894 | |
| GSE97050 | RPLP2 | 6181 | A_23_P147888 | -0.2482 | 0.4534 | |
| SRP007169 | RPLP2 | 6181 | RNAseq | -0.9277 | 0.0045 | |
| SRP008496 | RPLP2 | 6181 | RNAseq | -0.7402 | 0.0053 | |
| SRP064894 | RPLP2 | 6181 | RNAseq | -0.4600 | 0.1847 | |
| SRP133303 | RPLP2 | 6181 | RNAseq | -0.5323 | 0.0008 | |
| SRP159526 | RPLP2 | 6181 | RNAseq | -0.8716 | 0.0000 | |
| SRP193095 | RPLP2 | 6181 | RNAseq | -0.8759 | 0.0000 | |
| SRP219564 | RPLP2 | 6181 | RNAseq | 0.0119 | 0.9758 | |
| TCGA | RPLP2 | 6181 | RNAseq | 0.0169 | 0.7529 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RPLP2 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of RPLP2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RPLP2 | 6181 | 1 | 11 | 18 | |
| GSE20123 | RPLP2 | 6181 | 1 | 12 | 17 | |
| GSE43470 | RPLP2 | 6181 | 1 | 10 | 32 | |
| GSE46452 | RPLP2 | 6181 | 7 | 8 | 44 | |
| GSE47630 | RPLP2 | 6181 | 4 | 12 | 24 | |
| GSE54993 | RPLP2 | 6181 | 3 | 1 | 66 | |
| GSE54994 | RPLP2 | 6181 | 1 | 12 | 40 | |
| GSE60625 | RPLP2 | 6181 | 0 | 0 | 11 | |
| GSE74703 | RPLP2 | 6181 | 1 | 8 | 27 | |
| GSE74704 | RPLP2 | 6181 | 0 | 8 | 12 | |
| TCGA | RPLP2 | 6181 | 8 | 38 | 50 |
Total number of gains: 27; Total number of losses: 120; Total Number of normals: 341.
Somatic mutations of RPLP2:
Generating mutation plots.
Highly correlated genes for RPLP2:
Showing top 20/220 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RPLP2 | RPL27A | 0.774951 | 10 | 0 | 9 |
| RPLP2 | RPS11 | 0.764936 | 8 | 0 | 8 |
| RPLP2 | CACNA1B | 0.732769 | 3 | 0 | 3 |
| RPLP2 | NUDT9 | 0.703539 | 3 | 0 | 3 |
| RPLP2 | PAK1IP1 | 0.694903 | 3 | 0 | 3 |
| RPLP2 | HEYL | 0.691743 | 4 | 0 | 4 |
| RPLP2 | QPCTL | 0.691574 | 3 | 0 | 3 |
| RPLP2 | DDX52 | 0.690657 | 3 | 0 | 3 |
| RPLP2 | HERPUD2 | 0.690607 | 3 | 0 | 3 |
| RPLP2 | KIAA0556 | 0.685353 | 3 | 0 | 3 |
| RPLP2 | NDUFAF2 | 0.683716 | 3 | 0 | 3 |
| RPLP2 | OPHN1 | 0.676598 | 6 | 0 | 6 |
| RPLP2 | HOXA3 | 0.671836 | 4 | 0 | 4 |
| RPLP2 | CCDC87 | 0.671464 | 3 | 0 | 3 |
| RPLP2 | IER3IP1 | 0.665015 | 4 | 0 | 4 |
| RPLP2 | GJB4 | 0.664632 | 3 | 0 | 3 |
| RPLP2 | SELPLG | 0.662643 | 3 | 0 | 3 |
| RPLP2 | NME6 | 0.659268 | 3 | 0 | 3 |
| RPLP2 | KCNK13 | 0.653742 | 3 | 0 | 3 |
| RPLP2 | GML | 0.651111 | 3 | 0 | 3 |
For details and further investigation, click here
