| Full name: cold inducible RNA binding protein | Alias Symbol: CIRP | ||
| Type: protein-coding gene | Cytoband: 19p13.3 | ||
| Entrez ID: 1153 | HGNC ID: HGNC:1982 | Ensembl Gene: ENSG00000099622 | OMIM ID: 602649 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of CIRBP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CIRBP | 1153 | 200810_s_at | -0.7111 | 0.0797 | |
| GSE20347 | CIRBP | 1153 | 200810_s_at | -0.5849 | 0.0024 | |
| GSE23400 | CIRBP | 1153 | 200811_at | -0.5119 | 0.0000 | |
| GSE26886 | CIRBP | 1153 | 200810_s_at | -0.0544 | 0.8320 | |
| GSE29001 | CIRBP | 1153 | 200810_s_at | -0.5245 | 0.1227 | |
| GSE38129 | CIRBP | 1153 | 200810_s_at | -0.6185 | 0.0000 | |
| GSE45670 | CIRBP | 1153 | 200810_s_at | -0.8668 | 0.0000 | |
| GSE53622 | CIRBP | 1153 | 62185 | -0.8669 | 0.0000 | |
| GSE53624 | CIRBP | 1153 | 62185 | -0.8585 | 0.0000 | |
| GSE63941 | CIRBP | 1153 | 200810_s_at | -0.5087 | 0.3259 | |
| GSE77861 | CIRBP | 1153 | 200810_s_at | -0.1021 | 0.6643 | |
| GSE97050 | CIRBP | 1153 | A_23_P142322 | -0.8550 | 0.0555 | |
| SRP007169 | CIRBP | 1153 | RNAseq | -1.6233 | 0.0000 | |
| SRP008496 | CIRBP | 1153 | RNAseq | -1.2259 | 0.0000 | |
| SRP064894 | CIRBP | 1153 | RNAseq | -0.4467 | 0.0604 | |
| SRP133303 | CIRBP | 1153 | RNAseq | -0.8120 | 0.0000 | |
| SRP159526 | CIRBP | 1153 | RNAseq | -0.5139 | 0.0347 | |
| SRP193095 | CIRBP | 1153 | RNAseq | -0.5903 | 0.0000 | |
| SRP219564 | CIRBP | 1153 | RNAseq | -0.3335 | 0.3600 | |
| TCGA | CIRBP | 1153 | RNAseq | -0.3187 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by CIRBP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CIRBP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CIRBP | 1153 | 4 | 6 | 20 | |
| GSE20123 | CIRBP | 1153 | 4 | 5 | 21 | |
| GSE43470 | CIRBP | 1153 | 1 | 11 | 31 | |
| GSE46452 | CIRBP | 1153 | 47 | 1 | 11 | |
| GSE47630 | CIRBP | 1153 | 5 | 7 | 28 | |
| GSE54993 | CIRBP | 1153 | 13 | 4 | 53 | |
| GSE54994 | CIRBP | 1153 | 8 | 15 | 30 | |
| GSE60625 | CIRBP | 1153 | 9 | 0 | 2 | |
| GSE74703 | CIRBP | 1153 | 1 | 8 | 27 | |
| GSE74704 | CIRBP | 1153 | 3 | 3 | 14 | |
| TCGA | CIRBP | 1153 | 7 | 25 | 64 |
Total number of gains: 102; Total number of losses: 85; Total Number of normals: 301.
Somatic mutations of CIRBP:
Generating mutation plots.
Highly correlated genes for CIRBP:
Showing top 20/1267 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CIRBP | MAMDC2 | 0.790037 | 5 | 0 | 5 |
| CIRBP | CLEC3B | 0.781141 | 3 | 0 | 3 |
| CIRBP | RAB9B | 0.777925 | 5 | 0 | 5 |
| CIRBP | EIF4E3 | 0.757187 | 5 | 0 | 5 |
| CIRBP | LINC01082 | 0.746759 | 4 | 0 | 4 |
| CIRBP | NEGR1 | 0.741407 | 5 | 0 | 5 |
| CIRBP | CLYBL | 0.739752 | 5 | 0 | 5 |
| CIRBP | C1QTNF7 | 0.734168 | 5 | 0 | 5 |
| CIRBP | ATF7 | 0.732522 | 4 | 0 | 4 |
| CIRBP | LRRK2 | 0.729929 | 5 | 0 | 5 |
| CIRBP | SLMAP | 0.729137 | 5 | 0 | 5 |
| CIRBP | CCDC7 | 0.729079 | 3 | 0 | 3 |
| CIRBP | RGS7BP | 0.728996 | 5 | 0 | 5 |
| CIRBP | GTPBP1 | 0.72519 | 3 | 0 | 3 |
| CIRBP | TMEM132C | 0.724898 | 3 | 0 | 3 |
| CIRBP | HLF | 0.722318 | 8 | 0 | 8 |
| CIRBP | CYP21A2 | 0.721132 | 3 | 0 | 3 |
| CIRBP | NR2F1 | 0.719304 | 3 | 0 | 3 |
| CIRBP | NFIA | 0.717149 | 6 | 0 | 5 |
| CIRBP | ANGPTL1 | 0.717106 | 6 | 0 | 5 |
For details and further investigation, click here
