AAMP

 

Full name: angio associated migratory cell protein Alias Symbol: 
Type: protein-coding gene Cytoband: 2q35
Entrez ID: 14 HGNC ID: HGNC:18 Ensembl Gene: ENSG00000127837 OMIM ID: 603488
Drug and gene relationship at DGIdb
Screen Evidence:
  • Knocking out of this gene by CRIPR/Cas9 screen found altered tolerance on DNA toxicity in Genotoxic Screens.

 

Expression of AAMP:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 AAMP 14 201511_at 0.0587 0.9011
GSE20347 AAMP 14 201511_at -0.1164 0.1908
GSE23400 AAMP 14 201511_at 0.0503 0.4020
GSE26886 AAMP 14 201511_at -0.4959 0.0045
GSE29001 AAMP 14 201511_at 0.0415 0.8492
GSE38129 AAMP 14 201511_at 0.0441 0.7148
GSE45670 AAMP 14 201511_at 0.0808 0.4357
GSE53622 AAMP 14 105639 -0.8857 0.0000
GSE53624 AAMP 14 105639 -0.7005 0.0000
GSE63941 AAMP 14 201511_at 0.6029 0.0156
GSE77861 AAMP 14 201511_at 0.2360 0.1601
GSE97050 AAMP 14 A_23_P56529 -0.6143 0.2069
SRP007169 AAMP 14 RNAseq -0.7125 0.0338
SRP008496 AAMP 14 RNAseq -0.6320 0.0007
SRP064894 AAMP 14 RNAseq -0.1129 0.5439
SRP133303 AAMP 14 RNAseq 0.0756 0.5612
SRP159526 AAMP 14 RNAseq 0.1058 0.6338
SRP193095 AAMP 14 RNAseq -0.3240 0.0025
SRP219564 AAMP 14 RNAseq -0.0183 0.9140
TCGA AAMP 14 RNAseq -0.0963 0.0307

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by AAMP expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of AAMP:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 AAMP 14 1 14 15
GSE20123 AAMP 14 1 13 16
GSE43470 AAMP 14 1 7 35
GSE46452 AAMP 14 0 5 54
GSE47630 AAMP 14 4 5 31
GSE54993 AAMP 14 1 2 67
GSE54994 AAMP 14 8 10 35
GSE60625 AAMP 14 0 3 8
GSE74703 AAMP 14 1 5 30
GSE74704 AAMP 14 1 7 12
TCGA AAMP 14 11 27 58

Total number of gains: 29; Total number of losses: 98; Total Number of normals: 361.  


 

Somatic mutations of AAMP:

 

Generating mutation plots.

 

Highly correlated genes for AAMP:

 

Showing top 20/245 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
AAMPPRPF38A0.753179303
AAMPSYPL10.717681303
AAMPPTGES20.710924404
AAMPBCOR0.687604403
AAMPUNG0.676797303
AAMPCOMMD20.669708303
AAMPC19orf530.664401303
AAMPECHS10.661659404
AAMPCASP20.657681303
AAMPPTGES30.649122303
AAMPFBXO80.645273303
AAMPRAB210.645086303
AAMPRAB11FIP10.644259404
AAMPTRMT1L0.643338303
AAMPMRPL380.636395403
AAMPRNF1260.629095403
AAMPDEGS20.627092303
AAMPKIAA05560.624968403
AAMPFGGY0.624873504
AAMPSND10.622756403

For details and further investigation, click here