| Full name: mitochondrial ribosomal protein L39 | Alias Symbol: RPML5|MRP-L5|MGC104174|PRED66|PRED22|C21orf92|L39mt|MSTP003|MGC3400|FLJ20451 | ||
| Type: protein-coding gene | Cytoband: 21q21.3 | ||
| Entrez ID: 54148 | HGNC ID: HGNC:14027 | Ensembl Gene: ENSG00000154719 | OMIM ID: 611845 |
Screen Evidence:
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Expression of MRPL39:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MRPL39 | 54148 | 218558_s_at | -0.3327 | 0.5919 | |
| GSE20347 | MRPL39 | 54148 | 218558_s_at | -0.5188 | 0.0043 | |
| GSE23400 | MRPL39 | 54148 | 218558_s_at | -0.2759 | 0.0000 | |
| GSE26886 | MRPL39 | 54148 | 218558_s_at | -1.2808 | 0.0000 | |
| GSE29001 | MRPL39 | 54148 | 218558_s_at | -0.1475 | 0.6696 | |
| GSE38129 | MRPL39 | 54148 | 218558_s_at | -0.2443 | 0.1097 | |
| GSE45670 | MRPL39 | 54148 | 218558_s_at | -0.2472 | 0.1543 | |
| GSE63941 | MRPL39 | 54148 | 218558_s_at | 0.5511 | 0.1613 | |
| GSE77861 | MRPL39 | 54148 | 218558_s_at | -0.9032 | 0.0009 | |
| GSE97050 | MRPL39 | 54148 | A_23_P143446 | -0.2970 | 0.2601 | |
| SRP007169 | MRPL39 | 54148 | RNAseq | -1.0632 | 0.0013 | |
| SRP008496 | MRPL39 | 54148 | RNAseq | -0.5797 | 0.0102 | |
| SRP064894 | MRPL39 | 54148 | RNAseq | 0.0713 | 0.7330 | |
| SRP133303 | MRPL39 | 54148 | RNAseq | -0.4717 | 0.0045 | |
| SRP159526 | MRPL39 | 54148 | RNAseq | -0.3256 | 0.2598 | |
| SRP193095 | MRPL39 | 54148 | RNAseq | -0.7170 | 0.0000 | |
| SRP219564 | MRPL39 | 54148 | RNAseq | -0.5306 | 0.0233 | |
| TCGA | MRPL39 | 54148 | RNAseq | -0.0746 | 0.2359 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by MRPL39 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of MRPL39:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MRPL39 | 54148 | 2 | 11 | 17 | |
| GSE20123 | MRPL39 | 54148 | 2 | 11 | 17 | |
| GSE43470 | MRPL39 | 54148 | 2 | 8 | 33 | |
| GSE46452 | MRPL39 | 54148 | 1 | 21 | 37 | |
| GSE47630 | MRPL39 | 54148 | 6 | 17 | 17 | |
| GSE54993 | MRPL39 | 54148 | 9 | 2 | 59 | |
| GSE54994 | MRPL39 | 54148 | 2 | 8 | 43 | |
| GSE60625 | MRPL39 | 54148 | 0 | 0 | 11 | |
| GSE74703 | MRPL39 | 54148 | 2 | 6 | 28 | |
| GSE74704 | MRPL39 | 54148 | 2 | 7 | 11 | |
| TCGA | MRPL39 | 54148 | 9 | 38 | 49 |
Total number of gains: 37; Total number of losses: 129; Total Number of normals: 322.
Somatic mutations of MRPL39:
Generating mutation plots.
Highly correlated genes for MRPL39:
Showing top 20/1033 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MRPL39 | EIF4E3 | 0.804736 | 4 | 0 | 4 |
| MRPL39 | RPL27A | 0.800122 | 3 | 0 | 3 |
| MRPL39 | MRPS25 | 0.791583 | 3 | 0 | 3 |
| MRPL39 | TCAIM | 0.789076 | 4 | 0 | 4 |
| MRPL39 | ZNF416 | 0.776456 | 4 | 0 | 4 |
| MRPL39 | SLMAP | 0.76969 | 4 | 0 | 3 |
| MRPL39 | MIS18A | 0.767393 | 3 | 0 | 3 |
| MRPL39 | HECW2 | 0.756468 | 3 | 0 | 3 |
| MRPL39 | KRCC1 | 0.75506 | 4 | 0 | 4 |
| MRPL39 | ESYT2 | 0.754177 | 3 | 0 | 3 |
| MRPL39 | SAMD8 | 0.752953 | 3 | 0 | 3 |
| MRPL39 | CSDE1 | 0.748988 | 5 | 0 | 5 |
| MRPL39 | NDUFB8 | 0.74714 | 3 | 0 | 3 |
| MRPL39 | TP53RK | 0.742526 | 3 | 0 | 3 |
| MRPL39 | BRWD3 | 0.741588 | 3 | 0 | 3 |
| MRPL39 | ZNF395 | 0.740938 | 3 | 0 | 3 |
| MRPL39 | C2CD2 | 0.73989 | 3 | 0 | 3 |
| MRPL39 | OXNAD1 | 0.739752 | 6 | 0 | 6 |
| MRPL39 | EPG5 | 0.738795 | 4 | 0 | 4 |
| MRPL39 | C3orf80 | 0.738188 | 3 | 0 | 3 |
For details and further investigation, click here
