| Full name: leucine zipper and CTNNBIP1 domain containing | Alias Symbol: MGC15436 | ||
| Type: protein-coding gene | Cytoband: 1p36.22 | ||
| Entrez ID: 84328 | HGNC ID: HGNC:17497 | Ensembl Gene: ENSG00000162441 | OMIM ID: 610458 |
| Drug and gene relationship at DGIdb | |||
Expression of LZIC:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LZIC | 84328 | 226087_at | 0.1638 | 0.8195 | |
| GSE26886 | LZIC | 84328 | 226087_at | 0.6633 | 0.0486 | |
| GSE45670 | LZIC | 84328 | 226087_at | 0.3968 | 0.0164 | |
| GSE53622 | LZIC | 84328 | 10306 | -0.3300 | 0.0000 | |
| GSE53624 | LZIC | 84328 | 141687 | 0.2041 | 0.0010 | |
| GSE63941 | LZIC | 84328 | 226087_at | 0.1330 | 0.7701 | |
| GSE77861 | LZIC | 84328 | 226081_at | -0.0643 | 0.7433 | |
| GSE97050 | LZIC | 84328 | A_24_P268196 | -0.2849 | 0.3903 | |
| SRP007169 | LZIC | 84328 | RNAseq | -0.5526 | 0.1461 | |
| SRP008496 | LZIC | 84328 | RNAseq | -0.3564 | 0.1978 | |
| SRP064894 | LZIC | 84328 | RNAseq | 0.1788 | 0.2231 | |
| SRP133303 | LZIC | 84328 | RNAseq | 0.0309 | 0.8130 | |
| SRP159526 | LZIC | 84328 | RNAseq | 0.1009 | 0.7190 | |
| SRP193095 | LZIC | 84328 | RNAseq | -0.2923 | 0.0250 | |
| SRP219564 | LZIC | 84328 | RNAseq | -0.5590 | 0.0314 | |
| TCGA | LZIC | 84328 | RNAseq | 0.0158 | 0.7854 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by LZIC expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LZIC:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LZIC | 84328 | 0 | 5 | 25 | |
| GSE20123 | LZIC | 84328 | 0 | 3 | 27 | |
| GSE43470 | LZIC | 84328 | 6 | 5 | 32 | |
| GSE46452 | LZIC | 84328 | 7 | 1 | 51 | |
| GSE47630 | LZIC | 84328 | 8 | 4 | 28 | |
| GSE54993 | LZIC | 84328 | 3 | 1 | 66 | |
| GSE54994 | LZIC | 84328 | 12 | 4 | 37 | |
| GSE60625 | LZIC | 84328 | 0 | 0 | 11 | |
| GSE74703 | LZIC | 84328 | 5 | 3 | 28 | |
| GSE74704 | LZIC | 84328 | 0 | 0 | 20 | |
| TCGA | LZIC | 84328 | 10 | 24 | 62 |
Total number of gains: 51; Total number of losses: 50; Total Number of normals: 387.
Somatic mutations of LZIC:
Generating mutation plots.
Highly correlated genes for LZIC:
Showing top 20/280 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LZIC | SCAMP1 | 0.845502 | 3 | 0 | 3 |
| LZIC | PPM1A | 0.796348 | 3 | 0 | 3 |
| LZIC | BRAP | 0.787489 | 3 | 0 | 3 |
| LZIC | TRAPPC6B | 0.779985 | 3 | 0 | 3 |
| LZIC | TMEM186 | 0.754037 | 3 | 0 | 3 |
| LZIC | DHRS7 | 0.753005 | 3 | 0 | 3 |
| LZIC | AGPAT4 | 0.750483 | 3 | 0 | 3 |
| LZIC | PPP2R5E | 0.745496 | 4 | 0 | 3 |
| LZIC | PRPF38A | 0.741242 | 3 | 0 | 3 |
| LZIC | NDRG3 | 0.736941 | 3 | 0 | 3 |
| LZIC | ZNF354C | 0.735415 | 3 | 0 | 3 |
| LZIC | RPUSD4 | 0.730839 | 3 | 0 | 3 |
| LZIC | CDKL1 | 0.730186 | 3 | 0 | 3 |
| LZIC | LUC7L2 | 0.726625 | 3 | 0 | 3 |
| LZIC | RCHY1 | 0.720902 | 3 | 0 | 3 |
| LZIC | RRN3 | 0.72023 | 3 | 0 | 3 |
| LZIC | PSEN1 | 0.719145 | 5 | 0 | 4 |
| LZIC | ACBD5 | 0.718371 | 3 | 0 | 3 |
| LZIC | KDSR | 0.714649 | 3 | 0 | 3 |
| LZIC | PJA2 | 0.714301 | 3 | 0 | 3 |
For details and further investigation, click here
