| Full name: acylaminoacyl-peptide hydrolase | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 3p21.31 | ||
| Entrez ID: 327 | HGNC ID: HGNC:586 | Ensembl Gene: ENSG00000164062 | OMIM ID: 102645 |
| Drug and gene relationship at DGIdb | |||
Expression of APEH:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | APEH | 327 | 201284_s_at | 0.0313 | 0.9604 | |
| GSE20347 | APEH | 327 | 201284_s_at | -0.7498 | 0.0001 | |
| GSE23400 | APEH | 327 | 201284_s_at | -0.2536 | 0.0001 | |
| GSE26886 | APEH | 327 | 201284_s_at | -1.3190 | 0.0000 | |
| GSE29001 | APEH | 327 | 201284_s_at | -0.5517 | 0.1682 | |
| GSE38129 | APEH | 327 | 201284_s_at | -0.5190 | 0.0001 | |
| GSE45670 | APEH | 327 | 201284_s_at | -0.1197 | 0.4025 | |
| GSE53622 | APEH | 327 | 43229 | -0.4281 | 0.0000 | |
| GSE53624 | APEH | 327 | 43229 | -0.4583 | 0.0000 | |
| GSE63941 | APEH | 327 | 201284_s_at | 0.2486 | 0.4803 | |
| GSE77861 | APEH | 327 | 201284_s_at | -0.7505 | 0.0161 | |
| GSE97050 | APEH | 327 | A_23_P41143 | -0.1908 | 0.3604 | |
| SRP007169 | APEH | 327 | RNAseq | -0.8194 | 0.0549 | |
| SRP008496 | APEH | 327 | RNAseq | -0.8738 | 0.0002 | |
| SRP064894 | APEH | 327 | RNAseq | -0.0692 | 0.7240 | |
| SRP133303 | APEH | 327 | RNAseq | -0.3424 | 0.0653 | |
| SRP159526 | APEH | 327 | RNAseq | -0.6513 | 0.0072 | |
| SRP193095 | APEH | 327 | RNAseq | -0.6228 | 0.0000 | |
| SRP219564 | APEH | 327 | RNAseq | -0.5017 | 0.1132 | |
| TCGA | APEH | 327 | RNAseq | -0.2174 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by APEH expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of APEH:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | APEH | 327 | 0 | 18 | 12 | |
| GSE20123 | APEH | 327 | 0 | 19 | 11 | |
| GSE43470 | APEH | 327 | 0 | 18 | 25 | |
| GSE46452 | APEH | 327 | 2 | 16 | 41 | |
| GSE47630 | APEH | 327 | 1 | 24 | 15 | |
| GSE54993 | APEH | 327 | 6 | 2 | 62 | |
| GSE54994 | APEH | 327 | 0 | 36 | 17 | |
| GSE60625 | APEH | 327 | 5 | 0 | 6 | |
| GSE74703 | APEH | 327 | 0 | 14 | 22 | |
| GSE74704 | APEH | 327 | 0 | 12 | 8 | |
| TCGA | APEH | 327 | 0 | 78 | 18 |
Total number of gains: 14; Total number of losses: 237; Total Number of normals: 237.
Somatic mutations of APEH:
Generating mutation plots.
Highly correlated genes for APEH:
Showing top 20/1297 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| APEH | ACTR2 | 0.83752 | 3 | 0 | 3 |
| APEH | ZBTB7A | 0.822407 | 3 | 0 | 3 |
| APEH | C2orf16 | 0.791819 | 3 | 0 | 3 |
| APEH | GPR108 | 0.787118 | 3 | 0 | 3 |
| APEH | FAM83D | 0.781299 | 3 | 0 | 3 |
| APEH | TMEM50A | 0.774643 | 3 | 0 | 3 |
| APEH | CAPRIN1 | 0.774147 | 3 | 0 | 3 |
| APEH | ALKBH7 | 0.767175 | 4 | 0 | 4 |
| APEH | CIAPIN1 | 0.757336 | 4 | 0 | 4 |
| APEH | ZNF844 | 0.756282 | 3 | 0 | 3 |
| APEH | CLK3 | 0.750283 | 3 | 0 | 3 |
| APEH | TMEM120A | 0.747048 | 5 | 0 | 5 |
| APEH | TMEM117 | 0.744055 | 3 | 0 | 3 |
| APEH | CSNK2A2 | 0.742529 | 3 | 0 | 3 |
| APEH | ZNF175 | 0.739534 | 3 | 0 | 3 |
| APEH | CPEB4 | 0.738782 | 4 | 0 | 4 |
| APEH | ANO8 | 0.737632 | 3 | 0 | 3 |
| APEH | PRPF38A | 0.737501 | 3 | 0 | 3 |
| APEH | SLC25A46 | 0.736325 | 5 | 0 | 4 |
| APEH | TLR5 | 0.736236 | 3 | 0 | 3 |
For details and further investigation, click here
