| Full name: insulin like growth factor binding protein like 1 | Alias Symbol: bA113O24.1 | ||
| Type: protein-coding gene | Cytoband: 9p13.1 | ||
| Entrez ID: 347252 | HGNC ID: HGNC:20081 | Ensembl Gene: ENSG00000137142 | OMIM ID: 610413 |
| Drug and gene relationship at DGIdb | |||
Expression of IGFBPL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IGFBPL1 | 347252 | 227760_at | 0.4392 | 0.5685 | |
| GSE26886 | IGFBPL1 | 347252 | 227760_at | 0.5321 | 0.0098 | |
| GSE45670 | IGFBPL1 | 347252 | 227760_at | 0.3283 | 0.5101 | |
| GSE53622 | IGFBPL1 | 347252 | 14884 | 0.8724 | 0.0000 | |
| GSE53624 | IGFBPL1 | 347252 | 14884 | 0.7580 | 0.0000 | |
| GSE63941 | IGFBPL1 | 347252 | 227760_at | 0.7910 | 0.2440 | |
| GSE77861 | IGFBPL1 | 347252 | 227760_at | 0.0179 | 0.9041 | |
| SRP064894 | IGFBPL1 | 347252 | RNAseq | 1.1233 | 0.0007 | |
| SRP133303 | IGFBPL1 | 347252 | RNAseq | 0.3365 | 0.1073 | |
| SRP159526 | IGFBPL1 | 347252 | RNAseq | 2.4988 | 0.0001 | |
| SRP193095 | IGFBPL1 | 347252 | RNAseq | 0.6351 | 0.0036 | |
| SRP219564 | IGFBPL1 | 347252 | RNAseq | 1.1620 | 0.0243 | |
| TCGA | IGFBPL1 | 347252 | RNAseq | -0.2351 | 0.7118 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by IGFBPL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IGFBPL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IGFBPL1 | 347252 | 3 | 14 | 13 | |
| GSE20123 | IGFBPL1 | 347252 | 3 | 14 | 13 | |
| GSE43470 | IGFBPL1 | 347252 | 1 | 12 | 30 | |
| GSE46452 | IGFBPL1 | 347252 | 6 | 15 | 38 | |
| GSE47630 | IGFBPL1 | 347252 | 1 | 20 | 19 | |
| GSE54993 | IGFBPL1 | 347252 | 6 | 0 | 64 | |
| GSE54994 | IGFBPL1 | 347252 | 5 | 14 | 34 | |
| GSE60625 | IGFBPL1 | 347252 | 0 | 0 | 11 | |
| GSE74703 | IGFBPL1 | 347252 | 1 | 8 | 27 | |
| GSE74704 | IGFBPL1 | 347252 | 0 | 10 | 10 | |
| TCGA | IGFBPL1 | 347252 | 14 | 45 | 37 |
Total number of gains: 40; Total number of losses: 152; Total Number of normals: 296.
Somatic mutations of IGFBPL1:
Generating mutation plots.
Highly correlated genes for IGFBPL1:
Showing top 20/42 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IGFBPL1 | SLC10A4 | 0.734917 | 3 | 0 | 3 |
| IGFBPL1 | SLC45A3 | 0.6917 | 3 | 0 | 3 |
| IGFBPL1 | MAPKAPK5-AS1 | 0.665126 | 3 | 0 | 3 |
| IGFBPL1 | ZNHIT1 | 0.662794 | 3 | 0 | 3 |
| IGFBPL1 | RRH | 0.653718 | 3 | 0 | 3 |
| IGFBPL1 | ANKRD53 | 0.653469 | 3 | 0 | 3 |
| IGFBPL1 | WNT11 | 0.650138 | 4 | 0 | 3 |
| IGFBPL1 | GPR22 | 0.648941 | 3 | 0 | 3 |
| IGFBPL1 | BCL7C | 0.636838 | 3 | 0 | 3 |
| IGFBPL1 | DNM2 | 0.631168 | 3 | 0 | 3 |
| IGFBPL1 | SCMH1 | 0.606584 | 3 | 0 | 3 |
| IGFBPL1 | KCNS1 | 0.600363 | 3 | 0 | 3 |
| IGFBPL1 | LAMTOR4 | 0.59622 | 4 | 0 | 3 |
| IGFBPL1 | LRFN1 | 0.594907 | 3 | 0 | 3 |
| IGFBPL1 | RAB11B | 0.588669 | 3 | 0 | 3 |
| IGFBPL1 | FOXP4 | 0.588317 | 3 | 0 | 3 |
| IGFBPL1 | ST8SIA6-AS1 | 0.587424 | 4 | 0 | 3 |
| IGFBPL1 | AUTS2 | 0.58017 | 3 | 0 | 3 |
| IGFBPL1 | PODXL2 | 0.578466 | 3 | 0 | 3 |
| IGFBPL1 | CENPV | 0.57604 | 6 | 0 | 3 |
For details and further investigation, click here
