| Full name: radial spoke head component 1 | Alias Symbol: FLJ32753|RSP44|RSPH10A|CILD24 | ||
| Type: protein-coding gene | Cytoband: 21q22.3 | ||
| Entrez ID: 89765 | HGNC ID: HGNC:12371 | Ensembl Gene: ENSG00000160188 | OMIM ID: 609314 |
| Drug and gene relationship at DGIdb | |||
Expression of RSPH1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RSPH1 | 89765 | 230093_at | 0.0084 | 0.9884 | |
| GSE26886 | RSPH1 | 89765 | 230093_at | -0.0537 | 0.8630 | |
| GSE45670 | RSPH1 | 89765 | 230093_at | -0.2112 | 0.2386 | |
| GSE53622 | RSPH1 | 89765 | 57769 | -0.5775 | 0.0000 | |
| GSE53624 | RSPH1 | 89765 | 57769 | -0.5877 | 0.0000 | |
| GSE63941 | RSPH1 | 89765 | 230093_at | 0.6085 | 0.2667 | |
| GSE77861 | RSPH1 | 89765 | 230093_at | -0.2399 | 0.0888 | |
| GSE97050 | RSPH1 | 89765 | A_23_P102950 | -0.0724 | 0.7091 | |
| SRP133303 | RSPH1 | 89765 | RNAseq | 0.1366 | 0.6928 | |
| SRP159526 | RSPH1 | 89765 | RNAseq | 0.0912 | 0.9260 | |
| SRP219564 | RSPH1 | 89765 | RNAseq | -0.8276 | 0.0514 | |
| TCGA | RSPH1 | 89765 | RNAseq | -1.7563 | 0.0004 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by RSPH1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RSPH1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RSPH1 | 89765 | 2 | 8 | 20 | |
| GSE20123 | RSPH1 | 89765 | 2 | 8 | 20 | |
| GSE43470 | RSPH1 | 89765 | 0 | 13 | 30 | |
| GSE46452 | RSPH1 | 89765 | 1 | 21 | 37 | |
| GSE47630 | RSPH1 | 89765 | 6 | 17 | 17 | |
| GSE54993 | RSPH1 | 89765 | 8 | 1 | 61 | |
| GSE54994 | RSPH1 | 89765 | 4 | 8 | 41 | |
| GSE60625 | RSPH1 | 89765 | 0 | 0 | 11 | |
| GSE74703 | RSPH1 | 89765 | 0 | 10 | 26 | |
| GSE74704 | RSPH1 | 89765 | 1 | 4 | 15 | |
| TCGA | RSPH1 | 89765 | 7 | 40 | 49 |
Total number of gains: 31; Total number of losses: 130; Total Number of normals: 327.
Somatic mutations of RSPH1:
Generating mutation plots.
Highly correlated genes for RSPH1:
Showing top 20/33 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RSPH1 | SLC22A16 | 0.776255 | 3 | 0 | 3 |
| RSPH1 | BTNL9 | 0.711784 | 3 | 0 | 3 |
| RSPH1 | USH1C | 0.709703 | 3 | 0 | 3 |
| RSPH1 | FUT10 | 0.699009 | 4 | 0 | 3 |
| RSPH1 | MRPS16 | 0.694427 | 3 | 0 | 3 |
| RSPH1 | TKTL1 | 0.684961 | 3 | 0 | 3 |
| RSPH1 | RFESD | 0.673464 | 3 | 0 | 3 |
| RSPH1 | EXOSC1 | 0.646626 | 3 | 0 | 3 |
| RSPH1 | ALKBH2 | 0.641469 | 3 | 0 | 3 |
| RSPH1 | CLN3 | 0.626003 | 4 | 0 | 3 |
| RSPH1 | MANBAL | 0.619281 | 3 | 0 | 3 |
| RSPH1 | FAM189A2 | 0.608521 | 5 | 0 | 4 |
| RSPH1 | SNX21 | 0.598891 | 4 | 0 | 3 |
| RSPH1 | CCDC22 | 0.59519 | 4 | 0 | 3 |
| RSPH1 | BEND7 | 0.59019 | 5 | 0 | 4 |
| RSPH1 | LYPLA2 | 0.585389 | 3 | 0 | 3 |
| RSPH1 | PPOX | 0.584461 | 5 | 0 | 4 |
| RSPH1 | C16orf89 | 0.582144 | 4 | 0 | 3 |
| RSPH1 | AKR7A3 | 0.580841 | 4 | 0 | 3 |
| RSPH1 | TMEM198 | 0.577321 | 4 | 0 | 3 |
For details and further investigation, click here
