| Full name: kelch domain containing 7A | Alias Symbol: FLJ38753 | ||
| Type: protein-coding gene | Cytoband: 1p36.13 | ||
| Entrez ID: 127707 | HGNC ID: HGNC:26791 | Ensembl Gene: ENSG00000179023 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of KLHDC7A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KLHDC7A | 127707 | 1556012_at | -0.9067 | 0.0614 | |
| GSE26886 | KLHDC7A | 127707 | 1556012_at | -1.5891 | 0.0000 | |
| GSE45670 | KLHDC7A | 127707 | 1556012_at | -0.4306 | 0.2718 | |
| GSE53622 | KLHDC7A | 127707 | 123865 | 0.0179 | 0.9023 | |
| GSE53624 | KLHDC7A | 127707 | 123865 | -0.1263 | 0.1161 | |
| GSE63941 | KLHDC7A | 127707 | 1556012_at | 0.4379 | 0.5895 | |
| GSE77861 | KLHDC7A | 127707 | 1553437_at | -0.1785 | 0.1966 | |
| GSE97050 | KLHDC7A | 127707 | A_33_P3417765 | -0.1082 | 0.6806 | |
| SRP007169 | KLHDC7A | 127707 | RNAseq | -6.8428 | 0.0000 | |
| SRP064894 | KLHDC7A | 127707 | RNAseq | -2.3345 | 0.0001 | |
| SRP133303 | KLHDC7A | 127707 | RNAseq | -2.7637 | 0.0001 | |
| SRP159526 | KLHDC7A | 127707 | RNAseq | -3.9244 | 0.0000 | |
| SRP193095 | KLHDC7A | 127707 | RNAseq | -2.1410 | 0.0011 | |
| TCGA | KLHDC7A | 127707 | RNAseq | -2.5915 | 0.0004 |
Upregulated datasets: 0; Downregulated datasets: 7.
Survival by KLHDC7A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KLHDC7A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KLHDC7A | 127707 | 0 | 5 | 25 | |
| GSE20123 | KLHDC7A | 127707 | 0 | 4 | 26 | |
| GSE43470 | KLHDC7A | 127707 | 0 | 8 | 35 | |
| GSE46452 | KLHDC7A | 127707 | 5 | 1 | 53 | |
| GSE47630 | KLHDC7A | 127707 | 8 | 3 | 29 | |
| GSE54993 | KLHDC7A | 127707 | 3 | 1 | 66 | |
| GSE54994 | KLHDC7A | 127707 | 10 | 4 | 39 | |
| GSE60625 | KLHDC7A | 127707 | 0 | 0 | 11 | |
| GSE74703 | KLHDC7A | 127707 | 0 | 5 | 31 | |
| GSE74704 | KLHDC7A | 127707 | 0 | 0 | 20 | |
| TCGA | KLHDC7A | 127707 | 10 | 22 | 64 |
Total number of gains: 36; Total number of losses: 53; Total Number of normals: 399.
Somatic mutations of KLHDC7A:
Generating mutation plots.
Highly correlated genes for KLHDC7A:
Showing top 20/535 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KLHDC7A | PLEKHA7 | 0.785363 | 3 | 0 | 3 |
| KLHDC7A | CCNG2 | 0.781298 | 3 | 0 | 3 |
| KLHDC7A | CRISP3 | 0.780503 | 3 | 0 | 3 |
| KLHDC7A | FLG-AS1 | 0.77781 | 3 | 0 | 3 |
| KLHDC7A | C4orf3 | 0.772808 | 3 | 0 | 3 |
| KLHDC7A | TMPRSS11B | 0.768624 | 3 | 0 | 3 |
| KLHDC7A | FAM214A | 0.766352 | 3 | 0 | 3 |
| KLHDC7A | CAB39L | 0.766226 | 3 | 0 | 3 |
| KLHDC7A | SASH1 | 0.764934 | 3 | 0 | 3 |
| KLHDC7A | A2ML1 | 0.756718 | 3 | 0 | 3 |
| KLHDC7A | TTC9 | 0.755985 | 3 | 0 | 3 |
| KLHDC7A | SLURP1 | 0.755924 | 3 | 0 | 3 |
| KLHDC7A | SPAG17 | 0.755626 | 3 | 0 | 3 |
| KLHDC7A | SMIM5 | 0.753118 | 3 | 0 | 3 |
| KLHDC7A | ATP13A4 | 0.752131 | 3 | 0 | 3 |
| KLHDC7A | ATG9B | 0.747108 | 3 | 0 | 3 |
| KLHDC7A | USP6NL | 0.746693 | 3 | 0 | 3 |
| KLHDC7A | ATP6V0A4 | 0.746503 | 3 | 0 | 3 |
| KLHDC7A | CAPN14 | 0.745007 | 3 | 0 | 3 |
| KLHDC7A | ITSN2 | 0.744673 | 3 | 0 | 3 |
For details and further investigation, click here
