| Full name: Sin3A associated protein 130 | Alias Symbol: FLJ12761 | ||
| Type: protein-coding gene | Cytoband: 2q14.3 | ||
| Entrez ID: 79595 | HGNC ID: HGNC:29813 | Ensembl Gene: ENSG00000136715 | OMIM ID: 609697 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of SAP130:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SAP130 | 79595 | 220367_s_at | 0.0887 | 0.8706 | |
| GSE20347 | SAP130 | 79595 | 220367_s_at | -0.0256 | 0.8770 | |
| GSE23400 | SAP130 | 79595 | 220367_s_at | -0.0237 | 0.6596 | |
| GSE26886 | SAP130 | 79595 | 220367_s_at | -0.1227 | 0.4372 | |
| GSE29001 | SAP130 | 79595 | 220367_s_at | 0.1062 | 0.5880 | |
| GSE38129 | SAP130 | 79595 | 220367_s_at | 0.1211 | 0.3015 | |
| GSE45670 | SAP130 | 79595 | 220367_s_at | 0.0422 | 0.7940 | |
| GSE53622 | SAP130 | 79595 | 99452 | -0.0428 | 0.5749 | |
| GSE53624 | SAP130 | 79595 | 99452 | 0.0655 | 0.3107 | |
| GSE63941 | SAP130 | 79595 | 220367_s_at | 0.6666 | 0.1207 | |
| GSE77861 | SAP130 | 79595 | 220367_s_at | 0.2017 | 0.2213 | |
| GSE97050 | SAP130 | 79595 | A_23_P154188 | 0.1313 | 0.5639 | |
| SRP007169 | SAP130 | 79595 | RNAseq | 0.1319 | 0.6975 | |
| SRP008496 | SAP130 | 79595 | RNAseq | 0.0866 | 0.7053 | |
| SRP064894 | SAP130 | 79595 | RNAseq | 0.0416 | 0.8072 | |
| SRP133303 | SAP130 | 79595 | RNAseq | 0.0529 | 0.6813 | |
| SRP159526 | SAP130 | 79595 | RNAseq | 0.0315 | 0.9068 | |
| SRP193095 | SAP130 | 79595 | RNAseq | 0.1358 | 0.1780 | |
| SRP219564 | SAP130 | 79595 | RNAseq | -0.2170 | 0.4097 | |
| TCGA | SAP130 | 79595 | RNAseq | 0.0905 | 0.0633 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SAP130 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SAP130:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SAP130 | 79595 | 6 | 3 | 21 | |
| GSE20123 | SAP130 | 79595 | 6 | 3 | 21 | |
| GSE43470 | SAP130 | 79595 | 2 | 1 | 40 | |
| GSE46452 | SAP130 | 79595 | 1 | 3 | 55 | |
| GSE47630 | SAP130 | 79595 | 6 | 0 | 34 | |
| GSE54993 | SAP130 | 79595 | 0 | 6 | 64 | |
| GSE54994 | SAP130 | 79595 | 11 | 0 | 42 | |
| GSE60625 | SAP130 | 79595 | 0 | 3 | 8 | |
| GSE74703 | SAP130 | 79595 | 2 | 1 | 33 | |
| GSE74704 | SAP130 | 79595 | 3 | 1 | 16 | |
| TCGA | SAP130 | 79595 | 22 | 8 | 66 |
Total number of gains: 59; Total number of losses: 29; Total Number of normals: 400.
Somatic mutations of SAP130:
Generating mutation plots.
Highly correlated genes for SAP130:
Showing top 20/400 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SAP130 | ERI2 | 0.78415 | 3 | 0 | 3 |
| SAP130 | MED14 | 0.764371 | 3 | 0 | 3 |
| SAP130 | C17orf75 | 0.761317 | 3 | 0 | 3 |
| SAP130 | RRP1B | 0.747086 | 3 | 0 | 3 |
| SAP130 | C12orf66 | 0.744076 | 3 | 0 | 3 |
| SAP130 | RBM33 | 0.740844 | 3 | 0 | 3 |
| SAP130 | ZNF830 | 0.733535 | 3 | 0 | 3 |
| SAP130 | FADD | 0.729323 | 3 | 0 | 3 |
| SAP130 | THAP5 | 0.723654 | 3 | 0 | 3 |
| SAP130 | SLC25A14 | 0.723143 | 3 | 0 | 3 |
| SAP130 | SRRM1 | 0.718717 | 3 | 0 | 3 |
| SAP130 | NARS2 | 0.718425 | 3 | 0 | 3 |
| SAP130 | TET2 | 0.715235 | 3 | 0 | 3 |
| SAP130 | LGALS8 | 0.706598 | 4 | 0 | 3 |
| SAP130 | TAS2R19 | 0.705059 | 3 | 0 | 3 |
| SAP130 | GPKOW | 0.702421 | 3 | 0 | 3 |
| SAP130 | FASTKD3 | 0.702321 | 3 | 0 | 3 |
| SAP130 | PHTF2 | 0.700534 | 5 | 0 | 5 |
| SAP130 | SEMA4B | 0.696056 | 3 | 0 | 3 |
| SAP130 | ZNF689 | 0.688976 | 3 | 0 | 3 |
For details and further investigation, click here
