C12orf66

 

Full name: chromosome 12 open reading frame 66 Alias Symbol: FLJ32549
Type: protein-coding gene Cytoband: 12q14.2
Entrez ID: 144577 HGNC ID: HGNC:26517 Ensembl Gene: ENSG00000174206 OMIM ID: 617420
Drug and gene relationship at DGIdb

 

Expression of C12orf66:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 C12orf66 144577 1554067_at -0.2104 0.7235
GSE26886 C12orf66 144577 235026_at -0.2352 0.4094
GSE45670 C12orf66 144577 1554067_at -0.0255 0.9078
GSE53622 C12orf66 144577 51286 0.1721 0.0712
GSE53624 C12orf66 144577 51286 0.4862 0.0000
GSE63941 C12orf66 144577 1554067_at 1.0673 0.0413
GSE77861 C12orf66 144577 1554067_at 0.5864 0.2020
GSE97050 C12orf66 144577 A_23_P370569 0.1731 0.5823
SRP007169 C12orf66 144577 RNAseq 0.0206 0.9618
SRP008496 C12orf66 144577 RNAseq 0.2379 0.4346
SRP064894 C12orf66 144577 RNAseq 0.3205 0.1401
SRP133303 C12orf66 144577 RNAseq 0.7499 0.0294
SRP159526 C12orf66 144577 RNAseq 0.1631 0.4882
SRP193095 C12orf66 144577 RNAseq 0.1487 0.2704
SRP219564 C12orf66 144577 RNAseq 0.8037 0.0708
TCGA C12orf66 144577 RNAseq 0.2256 0.0047

Upregulated datasets: 1; Downregulated datasets: 0.  

 

Survival by C12orf66 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of C12orf66:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 C12orf66 144577 4 1 25
GSE20123 C12orf66 144577 4 1 25
GSE43470 C12orf66 144577 4 0 39
GSE46452 C12orf66 144577 10 0 49
GSE47630 C12orf66 144577 10 2 28
GSE54993 C12orf66 144577 0 5 65
GSE54994 C12orf66 144577 7 1 45
GSE60625 C12orf66 144577 0 0 11
GSE74703 C12orf66 144577 4 0 32
GSE74704 C12orf66 144577 3 1 16
TCGA C12orf66 144577 19 11 66

Total number of gains: 65; Total number of losses: 22; Total Number of normals: 401.  

 

Somatic mutations of C12orf66:

 

Generating mutation plots.

 

Highly correlated genes for C12orf66:

 

Showing top 20/464 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
C12orf66RMND10.803647303
C12orf66STX30.750964303
C12orf66SAP1300.744076303
C12orf66FRMD4B0.743941303
C12orf66DCTD0.726468303
C12orf66CBFB0.7258303
C12orf66GPN30.725262303
C12orf66HAUS10.72417303
C12orf66CLPX0.721542303
C12orf66SLC35A50.721505303
C12orf66IREB20.720387404
C12orf66RAC10.720241303
C12orf66TEX2610.716814303
C12orf66TBC1D20.715663303
C12orf66C5orf220.712039303
C12orf66ASCC10.711458303
C12orf66MRPL460.710834303
C12orf66NEU30.710649303
C12orf66PRDX30.707322303
C12orf66TMEM1230.706526303

For details and further investigation, click here