| Full name: asparaginyl-tRNA synthetase 2, mitochondrial | Alias Symbol: FLJ23441|SLM5 | ||
| Type: protein-coding gene | Cytoband: 11q14.1 | ||
| Entrez ID: 79731 | HGNC ID: HGNC:26274 | Ensembl Gene: ENSG00000137513 | OMIM ID: 612803 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of NARS2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NARS2 | 79731 | 219217_at | 0.3842 | 0.6898 | |
| GSE20347 | NARS2 | 79731 | 219217_at | 0.3507 | 0.1257 | |
| GSE23400 | NARS2 | 79731 | 219217_at | 0.4379 | 0.0000 | |
| GSE26886 | NARS2 | 79731 | 219217_at | -0.0886 | 0.8062 | |
| GSE29001 | NARS2 | 79731 | 219217_at | 0.0982 | 0.7667 | |
| GSE38129 | NARS2 | 79731 | 219217_at | 0.4452 | 0.0020 | |
| GSE45670 | NARS2 | 79731 | 219217_at | 0.2649 | 0.2568 | |
| GSE53622 | NARS2 | 79731 | 68941 | 0.5001 | 0.0000 | |
| GSE53624 | NARS2 | 79731 | 68941 | 0.4727 | 0.0000 | |
| GSE63941 | NARS2 | 79731 | 219217_at | 0.2797 | 0.6267 | |
| GSE77861 | NARS2 | 79731 | 219217_at | 0.2622 | 0.3670 | |
| GSE97050 | NARS2 | 79731 | A_23_P24960 | 0.4498 | 0.2484 | |
| SRP007169 | NARS2 | 79731 | RNAseq | 0.5672 | 0.2114 | |
| SRP008496 | NARS2 | 79731 | RNAseq | 0.5120 | 0.0981 | |
| SRP064894 | NARS2 | 79731 | RNAseq | 0.2792 | 0.1277 | |
| SRP133303 | NARS2 | 79731 | RNAseq | 0.1481 | 0.4272 | |
| SRP159526 | NARS2 | 79731 | RNAseq | 0.0273 | 0.9064 | |
| SRP193095 | NARS2 | 79731 | RNAseq | -0.0472 | 0.7847 | |
| SRP219564 | NARS2 | 79731 | RNAseq | 0.6643 | 0.1516 | |
| TCGA | NARS2 | 79731 | RNAseq | 0.0508 | 0.4804 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NARS2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NARS2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NARS2 | 79731 | 3 | 10 | 17 | |
| GSE20123 | NARS2 | 79731 | 3 | 10 | 17 | |
| GSE43470 | NARS2 | 79731 | 5 | 3 | 35 | |
| GSE46452 | NARS2 | 79731 | 7 | 22 | 30 | |
| GSE47630 | NARS2 | 79731 | 3 | 18 | 19 | |
| GSE54993 | NARS2 | 79731 | 8 | 2 | 60 | |
| GSE54994 | NARS2 | 79731 | 6 | 17 | 30 | |
| GSE60625 | NARS2 | 79731 | 4 | 3 | 4 | |
| GSE74703 | NARS2 | 79731 | 3 | 3 | 30 | |
| GSE74704 | NARS2 | 79731 | 3 | 6 | 11 | |
| TCGA | NARS2 | 79731 | 18 | 32 | 46 |
Total number of gains: 63; Total number of losses: 126; Total Number of normals: 299.
Somatic mutations of NARS2:
Generating mutation plots.
Highly correlated genes for NARS2:
Showing top 20/671 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NARS2 | UNC45A | 0.77347 | 3 | 0 | 3 |
| NARS2 | ABCB6 | 0.747649 | 3 | 0 | 3 |
| NARS2 | MAP4K3 | 0.745213 | 3 | 0 | 3 |
| NARS2 | FBXL19 | 0.732647 | 3 | 0 | 3 |
| NARS2 | ALG8 | 0.727737 | 13 | 0 | 12 |
| NARS2 | TPMT | 0.723511 | 3 | 0 | 3 |
| NARS2 | SLC38A10 | 0.719426 | 3 | 0 | 3 |
| NARS2 | SAP130 | 0.718425 | 3 | 0 | 3 |
| NARS2 | FAM111B | 0.716814 | 3 | 0 | 3 |
| NARS2 | DIS3L | 0.715941 | 3 | 0 | 3 |
| NARS2 | RNF26 | 0.71341 | 4 | 0 | 3 |
| NARS2 | ARHGEF11 | 0.712698 | 3 | 0 | 3 |
| NARS2 | TATDN2 | 0.712286 | 3 | 0 | 3 |
| NARS2 | CCDC126 | 0.712068 | 3 | 0 | 3 |
| NARS2 | GPD2 | 0.70516 | 3 | 0 | 3 |
| NARS2 | INTS4 | 0.703543 | 8 | 0 | 7 |
| NARS2 | ANKS6 | 0.702888 | 4 | 0 | 3 |
| NARS2 | SLC35B2 | 0.697051 | 3 | 0 | 3 |
| NARS2 | SP4 | 0.696744 | 3 | 0 | 3 |
| NARS2 | CLNS1A | 0.693347 | 13 | 0 | 12 |
For details and further investigation, click here
