| Full name: FAST kinase domains 3 | Alias Symbol: MGC5297|FLJ23274 | ||
| Type: protein-coding gene | Cytoband: 5p15.31 | ||
| Entrez ID: 79072 | HGNC ID: HGNC:28758 | Ensembl Gene: ENSG00000124279 | OMIM ID: 617530 |
| Drug and gene relationship at DGIdb | |||
Expression of FASTKD3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FASTKD3 | 79072 | 219200_at | 0.9155 | 0.0739 | |
| GSE20347 | FASTKD3 | 79072 | 219200_at | 0.3603 | 0.0187 | |
| GSE23400 | FASTKD3 | 79072 | 219200_at | 0.6280 | 0.0000 | |
| GSE26886 | FASTKD3 | 79072 | 219200_at | 0.8982 | 0.0025 | |
| GSE29001 | FASTKD3 | 79072 | 219200_at | 0.4668 | 0.1819 | |
| GSE38129 | FASTKD3 | 79072 | 219200_at | 0.4727 | 0.0002 | |
| GSE45670 | FASTKD3 | 79072 | 219200_at | 0.5173 | 0.0020 | |
| GSE53622 | FASTKD3 | 79072 | 99808 | 0.5560 | 0.0000 | |
| GSE53624 | FASTKD3 | 79072 | 17683 | 0.5350 | 0.0000 | |
| GSE63941 | FASTKD3 | 79072 | 219200_at | 0.3482 | 0.5170 | |
| GSE77861 | FASTKD3 | 79072 | 219200_at | 0.5816 | 0.1847 | |
| GSE97050 | FASTKD3 | 79072 | A_23_P58489 | 0.3851 | 0.1619 | |
| SRP007169 | FASTKD3 | 79072 | RNAseq | 0.6563 | 0.2478 | |
| SRP008496 | FASTKD3 | 79072 | RNAseq | 0.8088 | 0.0430 | |
| SRP064894 | FASTKD3 | 79072 | RNAseq | 0.3583 | 0.0826 | |
| SRP133303 | FASTKD3 | 79072 | RNAseq | 0.6169 | 0.0010 | |
| SRP159526 | FASTKD3 | 79072 | RNAseq | 0.4895 | 0.1013 | |
| SRP193095 | FASTKD3 | 79072 | RNAseq | 0.0652 | 0.5939 | |
| SRP219564 | FASTKD3 | 79072 | RNAseq | 0.5803 | 0.2922 | |
| TCGA | FASTKD3 | 79072 | RNAseq | 0.2244 | 0.0012 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by FASTKD3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FASTKD3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FASTKD3 | 79072 | 12 | 0 | 18 | |
| GSE20123 | FASTKD3 | 79072 | 12 | 0 | 18 | |
| GSE43470 | FASTKD3 | 79072 | 16 | 0 | 27 | |
| GSE46452 | FASTKD3 | 79072 | 6 | 22 | 31 | |
| GSE47630 | FASTKD3 | 79072 | 6 | 11 | 23 | |
| GSE54993 | FASTKD3 | 79072 | 5 | 5 | 60 | |
| GSE54994 | FASTKD3 | 79072 | 29 | 1 | 23 | |
| GSE60625 | FASTKD3 | 79072 | 0 | 0 | 11 | |
| GSE74703 | FASTKD3 | 79072 | 12 | 0 | 24 | |
| GSE74704 | FASTKD3 | 79072 | 11 | 0 | 9 | |
| TCGA | FASTKD3 | 79072 | 57 | 4 | 35 |
Total number of gains: 166; Total number of losses: 43; Total Number of normals: 279.
Somatic mutations of FASTKD3:
Generating mutation plots.
Highly correlated genes for FASTKD3:
Showing top 20/1384 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FASTKD3 | EXOC8 | 0.792659 | 3 | 0 | 3 |
| FASTKD3 | ZNF121 | 0.770061 | 4 | 0 | 4 |
| FASTKD3 | XRN1 | 0.765905 | 3 | 0 | 3 |
| FASTKD3 | KPTN | 0.738489 | 3 | 0 | 3 |
| FASTKD3 | MRPS22 | 0.736961 | 3 | 0 | 3 |
| FASTKD3 | NUP35 | 0.736448 | 3 | 0 | 3 |
| FASTKD3 | NAA25 | 0.735987 | 3 | 0 | 3 |
| FASTKD3 | ZNF700 | 0.734408 | 3 | 0 | 3 |
| FASTKD3 | RBM26 | 0.731511 | 4 | 0 | 4 |
| FASTKD3 | CENPBD1 | 0.726662 | 3 | 0 | 3 |
| FASTKD3 | NUDT19 | 0.725009 | 4 | 0 | 4 |
| FASTKD3 | LRRC69 | 0.719326 | 3 | 0 | 3 |
| FASTKD3 | ANAPC4 | 0.716977 | 3 | 0 | 3 |
| FASTKD3 | POM121 | 0.716687 | 3 | 0 | 3 |
| FASTKD3 | TMTC3 | 0.709333 | 4 | 0 | 4 |
| FASTKD3 | SCFD1 | 0.706965 | 3 | 0 | 3 |
| FASTKD3 | ALS2 | 0.706273 | 4 | 0 | 3 |
| FASTKD3 | CCT5 | 0.704173 | 9 | 0 | 9 |
| FASTKD3 | MMS22L | 0.702481 | 3 | 0 | 3 |
| FASTKD3 | SAP130 | 0.702321 | 3 | 0 | 3 |
For details and further investigation, click here
