| Full name: Sin3A associated protein 18 | Alias Symbol: SAP18p|2HOR0202|MGC27131 | ||
| Type: protein-coding gene | Cytoband: 13q12.11 | ||
| Entrez ID: 10284 | HGNC ID: HGNC:10530 | Ensembl Gene: ENSG00000150459 | OMIM ID: 602949 |
| Drug and gene relationship at DGIdb | |||
Expression of SAP18:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SAP18 | 10284 | 208742_s_at | -0.4248 | 0.1509 | |
| GSE20347 | SAP18 | 10284 | 208742_s_at | -0.5407 | 0.0001 | |
| GSE23400 | SAP18 | 10284 | 208742_s_at | -0.4052 | 0.0000 | |
| GSE26886 | SAP18 | 10284 | 208742_s_at | -0.2311 | 0.2759 | |
| GSE29001 | SAP18 | 10284 | 208742_s_at | -0.5649 | 0.0525 | |
| GSE38129 | SAP18 | 10284 | 208742_s_at | -0.3773 | 0.0006 | |
| GSE45670 | SAP18 | 10284 | 208742_s_at | -0.3360 | 0.0040 | |
| GSE53622 | SAP18 | 10284 | 11167 | -1.5807 | 0.0000 | |
| GSE53624 | SAP18 | 10284 | 11167 | -1.4724 | 0.0000 | |
| GSE63941 | SAP18 | 10284 | 208742_s_at | 0.4477 | 0.0526 | |
| GSE77861 | SAP18 | 10284 | 208742_s_at | -0.3715 | 0.0149 | |
| GSE97050 | SAP18 | 10284 | A_24_P381555 | -0.9871 | 0.1058 | |
| SRP007169 | SAP18 | 10284 | RNAseq | -1.5002 | 0.0001 | |
| SRP008496 | SAP18 | 10284 | RNAseq | -1.1315 | 0.0000 | |
| SRP064894 | SAP18 | 10284 | RNAseq | -0.4627 | 0.0212 | |
| SRP133303 | SAP18 | 10284 | RNAseq | -0.4153 | 0.0156 | |
| SRP159526 | SAP18 | 10284 | RNAseq | -0.8098 | 0.0005 | |
| SRP193095 | SAP18 | 10284 | RNAseq | -0.7953 | 0.0000 | |
| SRP219564 | SAP18 | 10284 | RNAseq | -0.7613 | 0.0109 | |
| TCGA | SAP18 | 10284 | RNAseq | -0.0449 | 0.3221 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by SAP18 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SAP18:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SAP18 | 10284 | 1 | 14 | 15 | |
| GSE20123 | SAP18 | 10284 | 1 | 13 | 16 | |
| GSE43470 | SAP18 | 10284 | 2 | 13 | 28 | |
| GSE46452 | SAP18 | 10284 | 0 | 33 | 26 | |
| GSE47630 | SAP18 | 10284 | 3 | 26 | 11 | |
| GSE54993 | SAP18 | 10284 | 11 | 2 | 57 | |
| GSE54994 | SAP18 | 10284 | 1 | 13 | 39 | |
| GSE60625 | SAP18 | 10284 | 0 | 3 | 8 | |
| GSE74703 | SAP18 | 10284 | 2 | 10 | 24 | |
| GSE74704 | SAP18 | 10284 | 0 | 11 | 9 | |
| TCGA | SAP18 | 10284 | 6 | 43 | 47 |
Total number of gains: 27; Total number of losses: 181; Total Number of normals: 280.
Somatic mutations of SAP18:
Generating mutation plots.
Highly correlated genes for SAP18:
Showing top 20/1140 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SAP18 | ESYT2 | 0.800671 | 4 | 0 | 4 |
| SAP18 | CYP2U1 | 0.798599 | 3 | 0 | 3 |
| SAP18 | CLEC3B | 0.796581 | 3 | 0 | 3 |
| SAP18 | UBXN1 | 0.786839 | 3 | 0 | 3 |
| SAP18 | PDCD7 | 0.780329 | 3 | 0 | 3 |
| SAP18 | ZRANB1 | 0.771282 | 3 | 0 | 3 |
| SAP18 | GPRASP2 | 0.766543 | 3 | 0 | 3 |
| SAP18 | FAXDC2 | 0.762754 | 3 | 0 | 3 |
| SAP18 | MTIF3 | 0.761684 | 6 | 0 | 6 |
| SAP18 | FAM104B | 0.757613 | 4 | 0 | 4 |
| SAP18 | NR2F1 | 0.751964 | 3 | 0 | 3 |
| SAP18 | ZNF470 | 0.747178 | 3 | 0 | 3 |
| SAP18 | CYP21A2 | 0.745254 | 3 | 0 | 3 |
| SAP18 | HPSE2 | 0.72471 | 4 | 0 | 4 |
| SAP18 | ADH1C | 0.722719 | 4 | 0 | 4 |
| SAP18 | ZNF425 | 0.720396 | 4 | 0 | 4 |
| SAP18 | MPP7 | 0.716632 | 7 | 0 | 6 |
| SAP18 | SLITRK3 | 0.714948 | 5 | 0 | 5 |
| SAP18 | CUL2 | 0.711131 | 3 | 0 | 3 |
| SAP18 | PPP1R3B | 0.7088 | 4 | 0 | 4 |
For details and further investigation, click here
