| Full name: SLIT and NTRK like family member 3 | Alias Symbol: KIAA0848 | ||
| Type: protein-coding gene | Cytoband: 3q26.1 | ||
| Entrez ID: 22865 | HGNC ID: HGNC:23501 | Ensembl Gene: ENSG00000121871 | OMIM ID: 609679 |
| Drug and gene relationship at DGIdb | |||
Expression of SLITRK3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLITRK3 | 22865 | 206732_at | -0.7953 | 0.0828 | |
| GSE20347 | SLITRK3 | 22865 | 206732_at | -0.0279 | 0.7198 | |
| GSE23400 | SLITRK3 | 22865 | 206732_at | -0.3275 | 0.0000 | |
| GSE26886 | SLITRK3 | 22865 | 206732_at | 0.0366 | 0.7461 | |
| GSE29001 | SLITRK3 | 22865 | 206732_at | -0.1945 | 0.2289 | |
| GSE38129 | SLITRK3 | 22865 | 206732_at | -0.5546 | 0.0057 | |
| GSE45670 | SLITRK3 | 22865 | 206732_at | -1.4425 | 0.0000 | |
| GSE53622 | SLITRK3 | 22865 | 122275 | -3.2233 | 0.0000 | |
| GSE53624 | SLITRK3 | 22865 | 122275 | -3.0102 | 0.0000 | |
| GSE63941 | SLITRK3 | 22865 | 206732_at | -0.0796 | 0.6653 | |
| GSE77861 | SLITRK3 | 22865 | 206732_at | -0.0300 | 0.7865 | |
| GSE97050 | SLITRK3 | 22865 | A_23_P18362 | -1.8089 | 0.0834 | |
| SRP064894 | SLITRK3 | 22865 | RNAseq | -1.4754 | 0.0030 | |
| SRP133303 | SLITRK3 | 22865 | RNAseq | -2.1719 | 0.0016 | |
| SRP159526 | SLITRK3 | 22865 | RNAseq | -0.8491 | 0.2656 | |
| SRP219564 | SLITRK3 | 22865 | RNAseq | -2.0742 | 0.0931 | |
| TCGA | SLITRK3 | 22865 | RNAseq | -1.3742 | 0.0076 |
Upregulated datasets: 0; Downregulated datasets: 6.
Survival by SLITRK3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLITRK3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLITRK3 | 22865 | 21 | 0 | 9 | |
| GSE20123 | SLITRK3 | 22865 | 21 | 0 | 9 | |
| GSE43470 | SLITRK3 | 22865 | 23 | 0 | 20 | |
| GSE46452 | SLITRK3 | 22865 | 18 | 2 | 39 | |
| GSE47630 | SLITRK3 | 22865 | 27 | 2 | 11 | |
| GSE54993 | SLITRK3 | 22865 | 1 | 13 | 56 | |
| GSE54994 | SLITRK3 | 22865 | 41 | 0 | 12 | |
| GSE60625 | SLITRK3 | 22865 | 0 | 6 | 5 | |
| GSE74703 | SLITRK3 | 22865 | 19 | 0 | 17 | |
| GSE74704 | SLITRK3 | 22865 | 13 | 0 | 7 | |
| TCGA | SLITRK3 | 22865 | 78 | 0 | 18 |
Total number of gains: 262; Total number of losses: 23; Total Number of normals: 203.
Somatic mutations of SLITRK3:
Generating mutation plots.
Highly correlated genes for SLITRK3:
Showing top 20/1389 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLITRK3 | MYOCD | 0.88359 | 5 | 0 | 5 |
| SLITRK3 | SYNPO2 | 0.878996 | 5 | 0 | 5 |
| SLITRK3 | MRVI1 | 0.87462 | 5 | 0 | 5 |
| SLITRK3 | RAB9B | 0.870821 | 5 | 0 | 5 |
| SLITRK3 | MAMDC2 | 0.864854 | 5 | 0 | 5 |
| SLITRK3 | ANGPTL1 | 0.842237 | 6 | 0 | 6 |
| SLITRK3 | ASB5 | 0.836936 | 5 | 0 | 5 |
| SLITRK3 | CLEC3B | 0.836234 | 3 | 0 | 3 |
| SLITRK3 | SLMAP | 0.834594 | 5 | 0 | 5 |
| SLITRK3 | CADM2 | 0.833916 | 3 | 0 | 3 |
| SLITRK3 | CYP21A2 | 0.833777 | 3 | 0 | 3 |
| SLITRK3 | C3orf70 | 0.827721 | 5 | 0 | 5 |
| SLITRK3 | MSRB3 | 0.824177 | 5 | 0 | 5 |
| SLITRK3 | PPP1R12B | 0.813284 | 8 | 0 | 7 |
| SLITRK3 | PARD3B | 0.808524 | 4 | 0 | 4 |
| SLITRK3 | LRFN5 | 0.802031 | 4 | 0 | 4 |
| SLITRK3 | PTCHD1 | 0.801233 | 5 | 0 | 5 |
| SLITRK3 | EIF4E3 | 0.799033 | 5 | 0 | 5 |
| SLITRK3 | ABCA8 | 0.798963 | 7 | 0 | 7 |
| SLITRK3 | XKR4 | 0.797657 | 5 | 0 | 5 |
For details and further investigation, click here
