| Full name: zinc finger protein 425 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 7q36.1 | ||
| Entrez ID: 155054 | HGNC ID: HGNC:20690 | Ensembl Gene: ENSG00000204947 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ZNF425:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF425 | 155054 | 242684_at | -0.3606 | 0.1376 | |
| GSE26886 | ZNF425 | 155054 | 242684_at | -0.2439 | 0.0838 | |
| GSE45670 | ZNF425 | 155054 | 242684_at | -0.1366 | 0.2540 | |
| GSE53622 | ZNF425 | 155054 | 154378 | -1.0667 | 0.0000 | |
| GSE53624 | ZNF425 | 155054 | 154378 | -1.1341 | 0.0000 | |
| GSE63941 | ZNF425 | 155054 | 242684_at | 0.2895 | 0.3894 | |
| GSE77861 | ZNF425 | 155054 | 235565_at | 0.0018 | 0.9889 | |
| GSE97050 | ZNF425 | 155054 | A_24_P941166 | -0.4618 | 0.2056 | |
| SRP007169 | ZNF425 | 155054 | RNAseq | -1.7814 | 0.0004 | |
| SRP064894 | ZNF425 | 155054 | RNAseq | -1.2978 | 0.0000 | |
| SRP133303 | ZNF425 | 155054 | RNAseq | -0.6813 | 0.0001 | |
| SRP159526 | ZNF425 | 155054 | RNAseq | -1.4894 | 0.0000 | |
| SRP193095 | ZNF425 | 155054 | RNAseq | -0.9596 | 0.0000 | |
| SRP219564 | ZNF425 | 155054 | RNAseq | -1.2006 | 0.0026 | |
| TCGA | ZNF425 | 155054 | RNAseq | -0.5501 | 0.0004 |
Upregulated datasets: 0; Downregulated datasets: 6.
Survival by ZNF425 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF425:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF425 | 155054 | 2 | 3 | 25 | |
| GSE20123 | ZNF425 | 155054 | 2 | 3 | 25 | |
| GSE43470 | ZNF425 | 155054 | 2 | 5 | 36 | |
| GSE46452 | ZNF425 | 155054 | 7 | 2 | 50 | |
| GSE47630 | ZNF425 | 155054 | 6 | 8 | 26 | |
| GSE54993 | ZNF425 | 155054 | 3 | 3 | 64 | |
| GSE54994 | ZNF425 | 155054 | 5 | 8 | 40 | |
| GSE60625 | ZNF425 | 155054 | 0 | 0 | 11 | |
| GSE74703 | ZNF425 | 155054 | 2 | 4 | 30 | |
| GSE74704 | ZNF425 | 155054 | 1 | 3 | 16 | |
| TCGA | ZNF425 | 155054 | 26 | 27 | 43 |
Total number of gains: 56; Total number of losses: 66; Total Number of normals: 366.
Somatic mutations of ZNF425:
Generating mutation plots.
Highly correlated genes for ZNF425:
Showing top 20/685 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF425 | SLTM | 0.773533 | 3 | 0 | 3 |
| ZNF425 | PIK3C2A | 0.758137 | 3 | 0 | 3 |
| ZNF425 | GSTK1 | 0.747661 | 4 | 0 | 4 |
| ZNF425 | ROR1 | 0.727571 | 4 | 0 | 4 |
| ZNF425 | MTIF3 | 0.724201 | 3 | 0 | 3 |
| ZNF425 | CETN2 | 0.723155 | 3 | 0 | 3 |
| ZNF425 | SAP18 | 0.720396 | 4 | 0 | 4 |
| ZNF425 | HMGCL | 0.707126 | 4 | 0 | 3 |
| ZNF425 | MAGI1 | 0.702364 | 4 | 0 | 3 |
| ZNF425 | CLOCK | 0.700946 | 4 | 0 | 4 |
| ZNF425 | ARIH1 | 0.700141 | 3 | 0 | 3 |
| ZNF425 | OAT | 0.698865 | 3 | 0 | 3 |
| ZNF425 | ZNF862 | 0.696794 | 4 | 0 | 4 |
| ZNF425 | HLF | 0.695242 | 4 | 0 | 4 |
| ZNF425 | ARL1 | 0.693876 | 4 | 0 | 4 |
| ZNF425 | KCNAB1 | 0.68822 | 4 | 0 | 4 |
| ZNF425 | SHROOM3 | 0.68464 | 5 | 0 | 5 |
| ZNF425 | FAM172A | 0.684635 | 4 | 0 | 3 |
| ZNF425 | OMP | 0.683954 | 3 | 0 | 3 |
| ZNF425 | PAQR8 | 0.683357 | 5 | 0 | 4 |
For details and further investigation, click here
