| Full name: extended synaptotagmin 2 | Alias Symbol: KIAA1228|CHR2SYT | ||
| Type: protein-coding gene | Cytoband: 7q36.3 | ||
| Entrez ID: 57488 | HGNC ID: HGNC:22211 | Ensembl Gene: ENSG00000117868 | OMIM ID: 616691 |
| Drug and gene relationship at DGIdb | |||
Expression of ESYT2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ESYT2 | 57488 | 224699_s_at | -0.5617 | 0.1750 | |
| GSE26886 | ESYT2 | 57488 | 1558511_s_at | -1.3757 | 0.0000 | |
| GSE45670 | ESYT2 | 57488 | 224699_s_at | -0.1877 | 0.3051 | |
| GSE53622 | ESYT2 | 57488 | 75180 | -0.9421 | 0.0000 | |
| GSE53624 | ESYT2 | 57488 | 75180 | -0.5039 | 0.0000 | |
| GSE63941 | ESYT2 | 57488 | 224699_s_at | 0.0790 | 0.9132 | |
| GSE77861 | ESYT2 | 57488 | 224699_s_at | -0.2519 | 0.3194 | |
| GSE97050 | ESYT2 | 57488 | A_24_P132470 | -0.4622 | 0.1993 | |
| SRP007169 | ESYT2 | 57488 | RNAseq | -0.1262 | 0.7256 | |
| SRP008496 | ESYT2 | 57488 | RNAseq | -0.3571 | 0.0926 | |
| SRP064894 | ESYT2 | 57488 | RNAseq | -0.5944 | 0.0046 | |
| SRP133303 | ESYT2 | 57488 | RNAseq | -0.2996 | 0.0224 | |
| SRP159526 | ESYT2 | 57488 | RNAseq | -0.9837 | 0.0036 | |
| SRP193095 | ESYT2 | 57488 | RNAseq | -0.3110 | 0.0045 | |
| SRP219564 | ESYT2 | 57488 | RNAseq | -0.0741 | 0.8645 | |
| TCGA | ESYT2 | 57488 | RNAseq | -0.1809 | 0.0005 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by ESYT2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ESYT2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ESYT2 | 57488 | 3 | 3 | 24 | |
| GSE20123 | ESYT2 | 57488 | 2 | 3 | 25 | |
| GSE43470 | ESYT2 | 57488 | 2 | 5 | 36 | |
| GSE46452 | ESYT2 | 57488 | 7 | 2 | 50 | |
| GSE47630 | ESYT2 | 57488 | 6 | 9 | 25 | |
| GSE54993 | ESYT2 | 57488 | 3 | 3 | 64 | |
| GSE54994 | ESYT2 | 57488 | 8 | 9 | 36 | |
| GSE60625 | ESYT2 | 57488 | 0 | 0 | 11 | |
| GSE74703 | ESYT2 | 57488 | 2 | 4 | 30 | |
| GSE74704 | ESYT2 | 57488 | 1 | 3 | 16 | |
| TCGA | ESYT2 | 57488 | 28 | 26 | 42 |
Total number of gains: 62; Total number of losses: 67; Total Number of normals: 359.
Somatic mutations of ESYT2:
Generating mutation plots.
Highly correlated genes for ESYT2:
Showing top 20/1102 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ESYT2 | CA5B | 0.836416 | 3 | 0 | 3 |
| ESYT2 | CHMP5 | 0.81758 | 3 | 0 | 3 |
| ESYT2 | SAP18 | 0.800671 | 4 | 0 | 4 |
| ESYT2 | ALAS1 | 0.798841 | 3 | 0 | 3 |
| ESYT2 | MRVI1 | 0.793922 | 3 | 0 | 3 |
| ESYT2 | EEA1 | 0.7892 | 4 | 0 | 4 |
| ESYT2 | SLC22A15 | 0.784875 | 3 | 0 | 3 |
| ESYT2 | C16orf72 | 0.781388 | 3 | 0 | 3 |
| ESYT2 | RNLS | 0.778558 | 4 | 0 | 4 |
| ESYT2 | CLEC3B | 0.773263 | 3 | 0 | 3 |
| ESYT2 | CHMP2A | 0.773065 | 5 | 0 | 5 |
| ESYT2 | UBE2D2 | 0.772876 | 4 | 0 | 4 |
| ESYT2 | CFL2 | 0.772689 | 3 | 0 | 3 |
| ESYT2 | USP25 | 0.771456 | 4 | 0 | 4 |
| ESYT2 | NFIA | 0.770543 | 4 | 0 | 4 |
| ESYT2 | OSBPL8 | 0.770132 | 3 | 0 | 3 |
| ESYT2 | GHITM | 0.768732 | 4 | 0 | 4 |
| ESYT2 | TMEM126A | 0.768546 | 3 | 0 | 3 |
| ESYT2 | TRIP4 | 0.764737 | 3 | 0 | 3 |
| ESYT2 | S1PR1 | 0.763246 | 3 | 0 | 3 |
For details and further investigation, click here
