| Full name: small proline rich protein 2D | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1q21.3 | ||
| Entrez ID: 6703 | HGNC ID: HGNC:11264 | Ensembl Gene: ENSG00000163216 | OMIM ID: 617587 |
| Drug and gene relationship at DGIdb | |||
Expression of SPRR2D:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | SPRR2D | 6703 | 106899 | -1.9232 | 0.0000 | |
| GSE53624 | SPRR2D | 6703 | 106899 | -2.6139 | 0.0000 | |
| GSE97050 | SPRR2D | 6703 | A_33_P3322388 | 0.3918 | 0.4541 | |
| SRP007169 | SPRR2D | 6703 | RNAseq | -4.9439 | 0.0000 | |
| SRP008496 | SPRR2D | 6703 | RNAseq | -4.4486 | 0.0000 | |
| SRP064894 | SPRR2D | 6703 | RNAseq | -3.4418 | 0.0000 | |
| SRP133303 | SPRR2D | 6703 | RNAseq | -2.2631 | 0.0001 | |
| SRP159526 | SPRR2D | 6703 | RNAseq | -3.2988 | 0.0025 | |
| SRP219564 | SPRR2D | 6703 | RNAseq | -4.6085 | 0.0007 | |
| TCGA | SPRR2D | 6703 | RNAseq | 1.1744 | 0.0063 |
Upregulated datasets: 1; Downregulated datasets: 8.
Survival by SPRR2D expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SPRR2D:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SPRR2D | 6703 | 15 | 0 | 15 | |
| GSE20123 | SPRR2D | 6703 | 15 | 0 | 15 | |
| GSE43470 | SPRR2D | 6703 | 6 | 2 | 35 | |
| GSE46452 | SPRR2D | 6703 | 3 | 1 | 55 | |
| GSE47630 | SPRR2D | 6703 | 15 | 0 | 25 | |
| GSE54993 | SPRR2D | 6703 | 0 | 4 | 66 | |
| GSE54994 | SPRR2D | 6703 | 15 | 0 | 38 | |
| GSE60625 | SPRR2D | 6703 | 0 | 0 | 11 | |
| GSE74703 | SPRR2D | 6703 | 6 | 1 | 29 | |
| GSE74704 | SPRR2D | 6703 | 7 | 0 | 13 | |
| TCGA | SPRR2D | 6703 | 39 | 2 | 55 |
Total number of gains: 121; Total number of losses: 10; Total Number of normals: 357.
Somatic mutations of SPRR2D:
Generating mutation plots.
Highly correlated genes for SPRR2D:
Showing top 20/340 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SPRR2D | SPRR2E | 0.973226 | 4 | 0 | 4 |
| SPRR2D | SPRR2F | 0.97316 | 4 | 0 | 4 |
| SPRR2D | SPRR2A | 0.956749 | 4 | 0 | 4 |
| SPRR2D | GPR45 | 0.931978 | 3 | 0 | 3 |
| SPRR2D | SPRR1B | 0.900741 | 4 | 0 | 4 |
| SPRR2D | SPRR2B | 0.8745 | 4 | 0 | 4 |
| SPRR2D | CNFN | 0.873073 | 4 | 0 | 4 |
| SPRR2D | SBSN | 0.866456 | 4 | 0 | 4 |
| SPRR2D | SPRR1A | 0.857478 | 4 | 0 | 4 |
| SPRR2D | PGLYRP3 | 0.853937 | 3 | 0 | 3 |
| SPRR2D | IL36A | 0.842596 | 3 | 0 | 3 |
| SPRR2D | TGM1 | 0.83841 | 4 | 0 | 4 |
| SPRR2D | TMPRSS11E | 0.836763 | 3 | 0 | 3 |
| SPRR2D | C19orf57 | 0.829069 | 3 | 0 | 3 |
| SPRR2D | EPHX3 | 0.826157 | 3 | 0 | 3 |
| SPRR2D | GRHL3 | 0.818045 | 4 | 0 | 4 |
| SPRR2D | P2RX3 | 0.815928 | 3 | 0 | 3 |
| SPRR2D | CEACAM3 | 0.815291 | 3 | 0 | 3 |
| SPRR2D | CEACAM5 | 0.805812 | 3 | 0 | 3 |
| SPRR2D | CTNNBIP1 | 0.804945 | 3 | 0 | 3 |
For details and further investigation, click here
