| Full name: somatomedin B and thrombospondin type 1 domain containing | Alias Symbol: RPESP | ||
| Type: protein-coding gene | Cytoband: 8q21.11 | ||
| Entrez ID: 157869 | HGNC ID: HGNC:30362 | Ensembl Gene: ENSG00000164764 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of SBSPON:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SBSPON | 157869 | 235209_at | -0.9363 | 0.1417 | |
| GSE20347 | SBSPON | 157869 | 214725_at | 0.0505 | 0.7291 | |
| GSE23400 | SBSPON | 157869 | 214725_at | -0.0531 | 0.1301 | |
| GSE26886 | SBSPON | 157869 | 235209_at | 1.3306 | 0.0400 | |
| GSE29001 | SBSPON | 157869 | 214725_at | -0.2132 | 0.0570 | |
| GSE38129 | SBSPON | 157869 | 214725_at | -0.3910 | 0.1274 | |
| GSE45670 | SBSPON | 157869 | 235209_at | -1.0899 | 0.0465 | |
| GSE53622 | SBSPON | 157869 | 34077 | -1.4276 | 0.0000 | |
| GSE53624 | SBSPON | 157869 | 34077 | -0.3674 | 0.0172 | |
| GSE63941 | SBSPON | 157869 | 235210_s_at | 0.6909 | 0.3628 | |
| GSE77861 | SBSPON | 157869 | 235209_at | 0.3566 | 0.0446 | |
| SRP007169 | SBSPON | 157869 | RNAseq | 0.6210 | 0.4782 | |
| SRP008496 | SBSPON | 157869 | RNAseq | 3.0950 | 0.0079 | |
| SRP064894 | SBSPON | 157869 | RNAseq | -1.0843 | 0.0003 | |
| SRP133303 | SBSPON | 157869 | RNAseq | -1.3299 | 0.0000 | |
| SRP159526 | SBSPON | 157869 | RNAseq | 0.8974 | 0.2433 | |
| SRP193095 | SBSPON | 157869 | RNAseq | -0.0913 | 0.7046 | |
| SRP219564 | SBSPON | 157869 | RNAseq | -0.1012 | 0.8952 |
Upregulated datasets: 2; Downregulated datasets: 4.
Survival by SBSPON expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of SBSPON:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SBSPON | 157869 | 15 | 0 | 15 | |
| GSE20123 | SBSPON | 157869 | 16 | 0 | 14 | |
| GSE43470 | SBSPON | 157869 | 18 | 1 | 24 | |
| GSE46452 | SBSPON | 157869 | 21 | 1 | 37 | |
| GSE47630 | SBSPON | 157869 | 23 | 0 | 17 | |
| GSE54993 | SBSPON | 157869 | 0 | 19 | 51 | |
| GSE54994 | SBSPON | 157869 | 30 | 0 | 23 | |
| GSE60625 | SBSPON | 157869 | 0 | 4 | 7 | |
| GSE74703 | SBSPON | 157869 | 15 | 1 | 20 | |
| GSE74704 | SBSPON | 157869 | 11 | 0 | 9 | |
| TCGA | SBSPON | 157869 | 50 | 2 | 44 |
Total number of gains: 199; Total number of losses: 28; Total Number of normals: 261.
Somatic mutations of SBSPON:
Generating mutation plots.
Highly correlated genes for SBSPON:
Showing top 20/223 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SBSPON | GAS2 | 0.702709 | 3 | 0 | 3 |
| SBSPON | MICU3 | 0.675834 | 4 | 0 | 4 |
| SBSPON | PIPOX | 0.674811 | 3 | 0 | 3 |
| SBSPON | PLCB4 | 0.670392 | 8 | 0 | 7 |
| SBSPON | CASC15 | 0.668115 | 3 | 0 | 3 |
| SBSPON | TRIM52 | 0.645086 | 3 | 0 | 3 |
| SBSPON | DCLK1 | 0.642197 | 8 | 0 | 8 |
| SBSPON | GNPDA2 | 0.642107 | 3 | 0 | 3 |
| SBSPON | CYB5R3 | 0.640165 | 4 | 0 | 3 |
| SBSPON | SMOC2 | 0.638744 | 6 | 0 | 4 |
| SBSPON | EBF1 | 0.637294 | 4 | 0 | 4 |
| SBSPON | CLU | 0.634715 | 5 | 0 | 4 |
| SBSPON | TTC28 | 0.631777 | 6 | 0 | 5 |
| SBSPON | GRIA2 | 0.627827 | 3 | 0 | 3 |
| SBSPON | TCEAL3 | 0.622938 | 3 | 0 | 3 |
| SBSPON | SERTAD4-AS1 | 0.622892 | 5 | 0 | 5 |
| SBSPON | PRELP | 0.621441 | 3 | 0 | 3 |
| SBSPON | RASD1 | 0.617713 | 3 | 0 | 3 |
| SBSPON | TCF21 | 0.617622 | 5 | 0 | 4 |
| SBSPON | SCAMP1-AS1 | 0.610537 | 3 | 0 | 3 |
For details and further investigation, click here
