| Full name: tetratricopeptide repeat domain 28 | Alias Symbol: KIAA1043 | ||
| Type: protein-coding gene | Cytoband: 22q12.1 | ||
| Entrez ID: 23331 | HGNC ID: HGNC:29179 | Ensembl Gene: ENSG00000100154 | OMIM ID: 615098 |
| Drug and gene relationship at DGIdb | |||
Expression of TTC28:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TTC28 | 23331 | 213058_at | -0.9288 | 0.0900 | |
| GSE20347 | TTC28 | 23331 | 213058_at | -0.5327 | 0.0000 | |
| GSE23400 | TTC28 | 23331 | 213058_at | -0.2543 | 0.0005 | |
| GSE26886 | TTC28 | 23331 | 215146_s_at | -0.1322 | 0.7986 | |
| GSE29001 | TTC28 | 23331 | 213058_at | -0.3823 | 0.3060 | |
| GSE38129 | TTC28 | 23331 | 213058_at | -0.7622 | 0.0016 | |
| GSE45670 | TTC28 | 23331 | 213058_at | -1.4492 | 0.0000 | |
| GSE53622 | TTC28 | 23331 | 8724 | -0.7311 | 0.0000 | |
| GSE53624 | TTC28 | 23331 | 8724 | -0.6302 | 0.0000 | |
| GSE63941 | TTC28 | 23331 | 213058_at | -4.0179 | 0.0001 | |
| GSE77861 | TTC28 | 23331 | 213058_at | -0.1094 | 0.6242 | |
| GSE97050 | TTC28 | 23331 | A_33_P3544887 | 0.3125 | 0.2151 | |
| SRP007169 | TTC28 | 23331 | RNAseq | 1.4534 | 0.0126 | |
| SRP008496 | TTC28 | 23331 | RNAseq | 1.9467 | 0.0000 | |
| SRP064894 | TTC28 | 23331 | RNAseq | -0.1431 | 0.5735 | |
| SRP133303 | TTC28 | 23331 | RNAseq | -0.7270 | 0.0000 | |
| SRP159526 | TTC28 | 23331 | RNAseq | -0.0667 | 0.8148 | |
| SRP193095 | TTC28 | 23331 | RNAseq | 0.2542 | 0.1242 | |
| SRP219564 | TTC28 | 23331 | RNAseq | -0.2568 | 0.6289 | |
| TCGA | TTC28 | 23331 | RNAseq | -0.4464 | 0.0000 |
Upregulated datasets: 2; Downregulated datasets: 2.
Survival by TTC28 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TTC28:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TTC28 | 23331 | 3 | 5 | 22 | |
| GSE20123 | TTC28 | 23331 | 3 | 4 | 23 | |
| GSE43470 | TTC28 | 23331 | 3 | 6 | 34 | |
| GSE46452 | TTC28 | 23331 | 31 | 1 | 27 | |
| GSE47630 | TTC28 | 23331 | 8 | 5 | 27 | |
| GSE54993 | TTC28 | 23331 | 3 | 6 | 61 | |
| GSE54994 | TTC28 | 23331 | 12 | 8 | 33 | |
| GSE60625 | TTC28 | 23331 | 5 | 0 | 6 | |
| GSE74703 | TTC28 | 23331 | 3 | 5 | 28 | |
| GSE74704 | TTC28 | 23331 | 0 | 1 | 19 | |
| TCGA | TTC28 | 23331 | 27 | 16 | 53 |
Total number of gains: 98; Total number of losses: 57; Total Number of normals: 333.
Somatic mutations of TTC28:
Generating mutation plots.
Highly correlated genes for TTC28:
Showing top 20/743 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TTC28 | FIBIN | 0.82733 | 3 | 0 | 3 |
| TTC28 | LINC01279 | 0.807043 | 3 | 0 | 3 |
| TTC28 | LRRN4CL | 0.776748 | 5 | 0 | 5 |
| TTC28 | MAGI2-AS3 | 0.773437 | 5 | 0 | 5 |
| TTC28 | GFRA1 | 0.766955 | 5 | 0 | 5 |
| TTC28 | LRRK2 | 0.739757 | 5 | 0 | 5 |
| TTC28 | C1QTNF7 | 0.737571 | 4 | 0 | 4 |
| TTC28 | DCHS1 | 0.730714 | 6 | 0 | 6 |
| TTC28 | NKAPL | 0.730522 | 3 | 0 | 3 |
| TTC28 | FAM13C | 0.730123 | 4 | 0 | 3 |
| TTC28 | C11orf96 | 0.727337 | 3 | 0 | 3 |
| TTC28 | FENDRR | 0.724731 | 5 | 0 | 5 |
| TTC28 | ANGPTL1 | 0.724024 | 5 | 0 | 5 |
| TTC28 | C16orf89 | 0.722353 | 3 | 0 | 3 |
| TTC28 | CBX7 | 0.722036 | 9 | 0 | 8 |
| TTC28 | VIM | 0.719801 | 4 | 0 | 4 |
| TTC28 | CLIP3 | 0.716527 | 7 | 0 | 7 |
| TTC28 | MAN1C1 | 0.716353 | 8 | 0 | 8 |
| TTC28 | NFIX | 0.715164 | 6 | 0 | 6 |
| TTC28 | ZEB2 | 0.713054 | 7 | 0 | 7 |
For details and further investigation, click here
