| Full name: sodium voltage-gated channel beta subunit 3 | Alias Symbol: HSA243396 | ||
| Type: protein-coding gene | Cytoband: 11q24.1 | ||
| Entrez ID: 55800 | HGNC ID: HGNC:20665 | Ensembl Gene: ENSG00000166257 | OMIM ID: 608214 |
| Drug and gene relationship at DGIdb | |||
Expression of SCN3B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SCN3B | 55800 | 204722_at | -0.1971 | 0.6233 | |
| GSE20347 | SCN3B | 55800 | 204723_at | 0.1162 | 0.1649 | |
| GSE23400 | SCN3B | 55800 | 204722_at | 0.0103 | 0.8137 | |
| GSE26886 | SCN3B | 55800 | 204723_at | 0.2823 | 0.0978 | |
| GSE29001 | SCN3B | 55800 | 204722_at | 0.1610 | 0.5134 | |
| GSE38129 | SCN3B | 55800 | 204722_at | -0.0865 | 0.4543 | |
| GSE45670 | SCN3B | 55800 | 204722_at | 0.1732 | 0.5681 | |
| GSE53622 | SCN3B | 55800 | 4737 | -0.9229 | 0.0000 | |
| GSE53624 | SCN3B | 55800 | 4737 | -0.2359 | 0.2177 | |
| GSE63941 | SCN3B | 55800 | 204723_at | 0.0712 | 0.8827 | |
| GSE77861 | SCN3B | 55800 | 204723_at | 0.2423 | 0.2750 | |
| SRP064894 | SCN3B | 55800 | RNAseq | 0.3214 | 0.3340 | |
| SRP133303 | SCN3B | 55800 | RNAseq | -0.0321 | 0.8520 | |
| SRP159526 | SCN3B | 55800 | RNAseq | 0.3509 | 0.4519 | |
| SRP193095 | SCN3B | 55800 | RNAseq | 0.5165 | 0.0006 | |
| SRP219564 | SCN3B | 55800 | RNAseq | -0.1960 | 0.6354 | |
| TCGA | SCN3B | 55800 | RNAseq | -0.2488 | 0.3779 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SCN3B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SCN3B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SCN3B | 55800 | 0 | 13 | 17 | |
| GSE20123 | SCN3B | 55800 | 0 | 13 | 17 | |
| GSE43470 | SCN3B | 55800 | 2 | 7 | 34 | |
| GSE46452 | SCN3B | 55800 | 3 | 26 | 30 | |
| GSE47630 | SCN3B | 55800 | 2 | 19 | 19 | |
| GSE54993 | SCN3B | 55800 | 10 | 0 | 60 | |
| GSE54994 | SCN3B | 55800 | 5 | 19 | 29 | |
| GSE60625 | SCN3B | 55800 | 0 | 3 | 8 | |
| GSE74703 | SCN3B | 55800 | 1 | 5 | 30 | |
| GSE74704 | SCN3B | 55800 | 0 | 9 | 11 | |
| TCGA | SCN3B | 55800 | 6 | 50 | 40 |
Total number of gains: 29; Total number of losses: 164; Total Number of normals: 295.
Somatic mutations of SCN3B:
Generating mutation plots.
Highly correlated genes for SCN3B:
Showing top 20/76 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SCN3B | MYEF2 | 0.645884 | 4 | 0 | 3 |
| SCN3B | NHLH1 | 0.640498 | 3 | 0 | 3 |
| SCN3B | TRANK1 | 0.631337 | 3 | 0 | 3 |
| SCN3B | SEMA4G | 0.618214 | 4 | 0 | 3 |
| SCN3B | LINC01361 | 0.613402 | 3 | 0 | 3 |
| SCN3B | HABP4 | 0.608649 | 3 | 0 | 3 |
| SCN3B | EVC | 0.597632 | 4 | 0 | 3 |
| SCN3B | ERN2 | 0.594224 | 3 | 0 | 3 |
| SCN3B | B3GAT1 | 0.591796 | 4 | 0 | 3 |
| SCN3B | CDH10 | 0.591515 | 3 | 0 | 3 |
| SCN3B | SLC25A31 | 0.577693 | 3 | 0 | 3 |
| SCN3B | RPS6KA6 | 0.574915 | 5 | 0 | 4 |
| SCN3B | MRVI1 | 0.572921 | 4 | 0 | 3 |
| SCN3B | ZKSCAN8 | 0.571864 | 5 | 0 | 3 |
| SCN3B | RECK | 0.571708 | 5 | 0 | 5 |
| SCN3B | GAD2 | 0.568689 | 4 | 0 | 3 |
| SCN3B | MAP7D3 | 0.566747 | 4 | 0 | 4 |
| SCN3B | ZZEF1 | 0.5664 | 6 | 0 | 4 |
| SCN3B | ARHGAP24 | 0.565679 | 6 | 0 | 4 |
| SCN3B | LRRN4CL | 0.56527 | 3 | 0 | 3 |
For details and further investigation, click here
