TRANK1

 

Full name: tetratricopeptide repeat and ankyrin repeat containing 1 Alias Symbol: LBA1|KIAA0342
Type: protein-coding gene Cytoband: 3p22.2
Entrez ID: 9881 HGNC ID: HGNC:29011 Ensembl Gene: ENSG00000168016 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of TRANK1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 TRANK1 9881 213261_at 0.2949 0.5873
GSE20347 TRANK1 9881 213261_at 0.2506 0.0531
GSE23400 TRANK1 9881 213261_at 0.3707 0.0000
GSE26886 TRANK1 9881 213261_at 0.3616 0.0440
GSE29001 TRANK1 9881 213261_at 0.0313 0.8873
GSE38129 TRANK1 9881 213261_at 0.1927 0.1747
GSE45670 TRANK1 9881 213261_at 0.2956 0.0750
GSE53622 TRANK1 9881 12150 0.3622 0.0214
GSE53624 TRANK1 9881 12150 0.3380 0.0260
GSE63941 TRANK1 9881 213261_at 0.1481 0.8038
GSE77861 TRANK1 9881 213261_at -0.0591 0.6988
GSE97050 TRANK1 A_21_P0012440 0.4363 0.2394
SRP007169 TRANK1 9881 RNAseq 1.8409 0.0004
SRP008496 TRANK1 9881 RNAseq 1.7582 0.0000
SRP064894 TRANK1 9881 RNAseq 0.7219 0.0047
SRP133303 TRANK1 9881 RNAseq 0.4831 0.0053
SRP159526 TRANK1 9881 RNAseq -0.2287 0.5452
SRP193095 TRANK1 9881 RNAseq 0.0509 0.8568
SRP219564 TRANK1 9881 RNAseq 0.3565 0.5149
TCGA TRANK1 9881 RNAseq -0.0013 0.9878

Upregulated datasets: 2; Downregulated datasets: 0.  


 

Survival by TRANK1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of TRANK1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 TRANK1 9881 0 18 12
GSE20123 TRANK1 9881 0 18 12
GSE43470 TRANK1 9881 0 20 23
GSE46452 TRANK1 9881 2 17 40
GSE47630 TRANK1 9881 1 25 14
GSE54993 TRANK1 9881 6 3 61
GSE54994 TRANK1 9881 1 32 20
GSE60625 TRANK1 9881 5 0 6
GSE74703 TRANK1 9881 0 16 20
GSE74704 TRANK1 9881 0 12 8
TCGA TRANK1 9881 0 71 25

Total number of gains: 15; Total number of losses: 232; Total Number of normals: 241.  


 

Somatic mutations of TRANK1:

 

Generating mutation plots.

 

Highly correlated genes for TRANK1:

 

Showing top 20/285 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
TRANK1TMEM150B0.703864303
TRANK1CCR50.679727505
TRANK1GTSE10.677039303
TRANK1CD40.66198504
TRANK1PIK3CG0.658092404
TRANK1DCSTAMP0.656761303
TRANK1NOP140.656563303
TRANK1CMTM70.655661303
TRANK1PCGF10.649783303
TRANK1PLXNC10.64976605
TRANK1LRRC250.644916303
TRANK1TMEM1190.632215403
TRANK1SCN3B0.631337303
TRANK1CD270.630882504
TRANK1LAT0.629018403
TRANK1KLRD10.628657504
TRANK1IFITM10.627896807
TRANK1FPR30.627011706
TRANK1RNASE60.626395403
TRANK1ATG2A0.62379303

For details and further investigation, click here