| Full name: SCY1 like pseudokinase 2 | Alias Symbol: KIAA1360|CVAK104 | ||
| Type: protein-coding gene | Cytoband: 12q23.1 | ||
| Entrez ID: 55681 | HGNC ID: HGNC:19286 | Ensembl Gene: ENSG00000136021 | OMIM ID: 616365 |
| Drug and gene relationship at DGIdb | |||
Expression of SCYL2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SCYL2 | 55681 | 224960_at | -0.1798 | 0.6948 | |
| GSE20347 | SCYL2 | 55681 | 221220_s_at | -0.0534 | 0.6209 | |
| GSE23400 | SCYL2 | 55681 | 221220_s_at | -0.1504 | 0.0697 | |
| GSE26886 | SCYL2 | 55681 | 224960_at | -0.7212 | 0.0004 | |
| GSE29001 | SCYL2 | 55681 | 221220_s_at | -0.1558 | 0.3308 | |
| GSE38129 | SCYL2 | 55681 | 221220_s_at | -0.0199 | 0.9041 | |
| GSE45670 | SCYL2 | 55681 | 224960_at | -0.1635 | 0.2418 | |
| GSE53622 | SCYL2 | 55681 | 66439 | -0.0186 | 0.7564 | |
| GSE53624 | SCYL2 | 55681 | 78061 | -0.4478 | 0.0000 | |
| GSE63941 | SCYL2 | 55681 | 224960_at | -0.0201 | 0.9601 | |
| GSE77861 | SCYL2 | 55681 | 224960_at | -0.4091 | 0.1379 | |
| GSE97050 | SCYL2 | 55681 | A_33_P3292829 | -0.0431 | 0.8689 | |
| SRP007169 | SCYL2 | 55681 | RNAseq | -0.7944 | 0.0501 | |
| SRP008496 | SCYL2 | 55681 | RNAseq | -0.5892 | 0.0076 | |
| SRP064894 | SCYL2 | 55681 | RNAseq | -0.6096 | 0.0116 | |
| SRP133303 | SCYL2 | 55681 | RNAseq | 0.2200 | 0.1849 | |
| SRP159526 | SCYL2 | 55681 | RNAseq | -0.1452 | 0.5578 | |
| SRP193095 | SCYL2 | 55681 | RNAseq | -0.5678 | 0.0000 | |
| SRP219564 | SCYL2 | 55681 | RNAseq | -0.9482 | 0.0037 | |
| TCGA | SCYL2 | 55681 | RNAseq | -0.0175 | 0.7037 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SCYL2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SCYL2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SCYL2 | 55681 | 2 | 2 | 26 | |
| GSE20123 | SCYL2 | 55681 | 2 | 2 | 26 | |
| GSE43470 | SCYL2 | 55681 | 2 | 0 | 41 | |
| GSE46452 | SCYL2 | 55681 | 9 | 1 | 49 | |
| GSE47630 | SCYL2 | 55681 | 9 | 1 | 30 | |
| GSE54993 | SCYL2 | 55681 | 0 | 5 | 65 | |
| GSE54994 | SCYL2 | 55681 | 4 | 2 | 47 | |
| GSE60625 | SCYL2 | 55681 | 0 | 0 | 11 | |
| GSE74703 | SCYL2 | 55681 | 2 | 0 | 34 | |
| GSE74704 | SCYL2 | 55681 | 1 | 2 | 17 | |
| TCGA | SCYL2 | 55681 | 19 | 10 | 67 |
Total number of gains: 50; Total number of losses: 25; Total Number of normals: 413.
Somatic mutations of SCYL2:
Generating mutation plots.
Highly correlated genes for SCYL2:
Showing top 20/1156 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SCYL2 | CSNK1A1 | 0.794668 | 3 | 0 | 3 |
| SCYL2 | ZNF596 | 0.748144 | 3 | 0 | 3 |
| SCYL2 | VPS26A | 0.743968 | 5 | 0 | 5 |
| SCYL2 | CTTNBP2NL | 0.740131 | 6 | 0 | 6 |
| SCYL2 | RBX1 | 0.737692 | 3 | 0 | 3 |
| SCYL2 | ANKHD1 | 0.73367 | 3 | 0 | 3 |
| SCYL2 | ZNF585A | 0.731914 | 3 | 0 | 3 |
| SCYL2 | ATP6V1G1 | 0.726485 | 3 | 0 | 3 |
| SCYL2 | TSPYL1 | 0.725011 | 4 | 0 | 4 |
| SCYL2 | RAB18 | 0.722216 | 4 | 0 | 4 |
| SCYL2 | STK38 | 0.718023 | 4 | 0 | 4 |
| SCYL2 | SS18 | 0.718018 | 3 | 0 | 3 |
| SCYL2 | CMTR2 | 0.716731 | 4 | 0 | 3 |
| SCYL2 | CRBN | 0.71655 | 3 | 0 | 3 |
| SCYL2 | SYAP1 | 0.714244 | 6 | 0 | 6 |
| SCYL2 | LIN54 | 0.709763 | 3 | 0 | 3 |
| SCYL2 | TAB3 | 0.706171 | 6 | 0 | 6 |
| SCYL2 | ATG13 | 0.705539 | 3 | 0 | 3 |
| SCYL2 | ZNF92 | 0.704597 | 3 | 0 | 3 |
| SCYL2 | GRHL3 | 0.703525 | 5 | 0 | 5 |
For details and further investigation, click here
