| Full name: VPS26, retromer complex component A | Alias Symbol: Hbeta58|PEP8A | ||
| Type: protein-coding gene | Cytoband: 10q22.1 | ||
| Entrez ID: 9559 | HGNC ID: HGNC:12711 | Ensembl Gene: ENSG00000122958 | OMIM ID: 605506 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of VPS26A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | VPS26A | 9559 | 201807_at | -0.1391 | 0.6951 | |
| GSE20347 | VPS26A | 9559 | 201807_at | -0.3746 | 0.0002 | |
| GSE23400 | VPS26A | 9559 | 201807_at | -0.2011 | 0.0018 | |
| GSE26886 | VPS26A | 9559 | 201807_at | -0.5711 | 0.0068 | |
| GSE29001 | VPS26A | 9559 | 201807_at | -0.3030 | 0.3153 | |
| GSE38129 | VPS26A | 9559 | 201807_at | -0.2304 | 0.0049 | |
| GSE45670 | VPS26A | 9559 | 201807_at | -0.2390 | 0.0093 | |
| GSE53622 | VPS26A | 9559 | 110260 | -0.3833 | 0.0000 | |
| GSE53624 | VPS26A | 9559 | 110260 | -0.4447 | 0.0000 | |
| GSE63941 | VPS26A | 9559 | 201807_at | 0.1645 | 0.7145 | |
| GSE77861 | VPS26A | 9559 | 201807_at | -0.2992 | 0.1471 | |
| GSE97050 | VPS26A | 9559 | A_23_P75255 | -0.0699 | 0.7548 | |
| SRP007169 | VPS26A | 9559 | RNAseq | -0.7187 | 0.0972 | |
| SRP008496 | VPS26A | 9559 | RNAseq | -0.5110 | 0.0105 | |
| SRP064894 | VPS26A | 9559 | RNAseq | -0.6458 | 0.0000 | |
| SRP133303 | VPS26A | 9559 | RNAseq | 0.0340 | 0.8028 | |
| SRP159526 | VPS26A | 9559 | RNAseq | -0.5693 | 0.1020 | |
| SRP193095 | VPS26A | 9559 | RNAseq | -0.5480 | 0.0000 | |
| SRP219564 | VPS26A | 9559 | RNAseq | -0.5184 | 0.0659 | |
| TCGA | VPS26A | 9559 | RNAseq | 0.0661 | 0.1521 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by VPS26A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of VPS26A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | VPS26A | 9559 | 3 | 4 | 23 | |
| GSE20123 | VPS26A | 9559 | 3 | 3 | 24 | |
| GSE43470 | VPS26A | 9559 | 1 | 7 | 35 | |
| GSE46452 | VPS26A | 9559 | 0 | 11 | 48 | |
| GSE47630 | VPS26A | 9559 | 2 | 14 | 24 | |
| GSE54993 | VPS26A | 9559 | 8 | 0 | 62 | |
| GSE54994 | VPS26A | 9559 | 2 | 12 | 39 | |
| GSE60625 | VPS26A | 9559 | 0 | 0 | 11 | |
| GSE74703 | VPS26A | 9559 | 1 | 4 | 31 | |
| GSE74704 | VPS26A | 9559 | 1 | 1 | 18 | |
| TCGA | VPS26A | 9559 | 11 | 22 | 63 |
Total number of gains: 32; Total number of losses: 78; Total Number of normals: 378.
Somatic mutations of VPS26A:
Generating mutation plots.
Highly correlated genes for VPS26A:
Showing top 20/1155 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| VPS26A | PSMD1 | 0.847189 | 3 | 0 | 3 |
| VPS26A | PRPF38A | 0.798036 | 4 | 0 | 4 |
| VPS26A | RHBDD1 | 0.792184 | 3 | 0 | 3 |
| VPS26A | MRPL20 | 0.783652 | 3 | 0 | 3 |
| VPS26A | NOA1 | 0.769514 | 3 | 0 | 3 |
| VPS26A | SRP68 | 0.769192 | 4 | 0 | 4 |
| VPS26A | PRADC1 | 0.765594 | 3 | 0 | 3 |
| VPS26A | NANS | 0.762634 | 3 | 0 | 3 |
| VPS26A | COX10 | 0.756611 | 3 | 0 | 3 |
| VPS26A | CNOT10 | 0.752745 | 3 | 0 | 3 |
| VPS26A | HDHD2 | 0.746909 | 3 | 0 | 3 |
| VPS26A | WDR77 | 0.745389 | 3 | 0 | 3 |
| VPS26A | ZRANB2 | 0.74535 | 3 | 0 | 3 |
| VPS26A | TYW3 | 0.744684 | 3 | 0 | 3 |
| VPS26A | SCYL2 | 0.743968 | 5 | 0 | 5 |
| VPS26A | ZNF543 | 0.728217 | 3 | 0 | 3 |
| VPS26A | MKRN1 | 0.72801 | 4 | 0 | 4 |
| VPS26A | EIF2B1 | 0.72553 | 4 | 0 | 4 |
| VPS26A | REPS1 | 0.723705 | 3 | 0 | 3 |
| VPS26A | MRPS11 | 0.723591 | 4 | 0 | 4 |
For details and further investigation, click here
