| Full name: cap methyltransferase 2 | Alias Symbol: FLJ11171|AFT|MTr2 | ||
| Type: protein-coding gene | Cytoband: 16q22.2 | ||
| Entrez ID: 55783 | HGNC ID: HGNC:25635 | Ensembl Gene: ENSG00000180917 | OMIM ID: 616190 |
Screen Evidence:
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Expression of CMTR2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CMTR2 | 55783 | 222811_at | -0.1933 | 0.8229 | |
| GSE26886 | CMTR2 | 55783 | 222811_at | -1.3710 | 0.0000 | |
| GSE45670 | CMTR2 | 55783 | 222811_at | 0.1465 | 0.4067 | |
| GSE53622 | CMTR2 | 55783 | 42427 | 0.0031 | 0.9691 | |
| GSE53624 | CMTR2 | 55783 | 42427 | -0.3312 | 0.0000 | |
| GSE63941 | CMTR2 | 55783 | 222811_at | -0.2748 | 0.5996 | |
| GSE77861 | CMTR2 | 55783 | 222811_at | -0.4183 | 0.3170 | |
| SRP007169 | CMTR2 | 55783 | RNAseq | -0.9930 | 0.0025 | |
| SRP008496 | CMTR2 | 55783 | RNAseq | -0.8707 | 0.0002 | |
| SRP064894 | CMTR2 | 55783 | RNAseq | -0.6152 | 0.0138 | |
| SRP133303 | CMTR2 | 55783 | RNAseq | -0.1257 | 0.3504 | |
| SRP159526 | CMTR2 | 55783 | RNAseq | -0.6721 | 0.0207 | |
| SRP193095 | CMTR2 | 55783 | RNAseq | -0.7266 | 0.0000 | |
| SRP219564 | CMTR2 | 55783 | RNAseq | -0.9634 | 0.0253 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by CMTR2 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of CMTR2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CMTR2 | 55783 | 4 | 0 | 26 | |
| GSE20123 | CMTR2 | 55783 | 4 | 0 | 26 | |
| GSE43470 | CMTR2 | 55783 | 2 | 8 | 33 | |
| GSE46452 | CMTR2 | 55783 | 38 | 2 | 19 | |
| GSE47630 | CMTR2 | 55783 | 11 | 8 | 21 | |
| GSE54993 | CMTR2 | 55783 | 2 | 4 | 64 | |
| GSE54994 | CMTR2 | 55783 | 8 | 10 | 35 | |
| GSE60625 | CMTR2 | 55783 | 4 | 0 | 7 | |
| GSE74703 | CMTR2 | 55783 | 2 | 5 | 29 | |
| GSE74704 | CMTR2 | 55783 | 2 | 0 | 18 |
Total number of gains: 77; Total number of losses: 37; Total Number of normals: 278.
Somatic mutations of CMTR2:
Generating mutation plots.
Highly correlated genes for CMTR2:
Showing top 20/480 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CMTR2 | TRIP12 | 0.818001 | 3 | 0 | 3 |
| CMTR2 | CLCN3 | 0.817744 | 3 | 0 | 3 |
| CMTR2 | ABHD5 | 0.754045 | 3 | 0 | 3 |
| CMTR2 | LYSMD3 | 0.753674 | 3 | 0 | 3 |
| CMTR2 | GRPEL2 | 0.752663 | 3 | 0 | 3 |
| CMTR2 | TMEM45B | 0.74298 | 3 | 0 | 3 |
| CMTR2 | CAB39 | 0.739837 | 3 | 0 | 3 |
| CMTR2 | VPS4B | 0.733045 | 4 | 0 | 3 |
| CMTR2 | TIAM1 | 0.732593 | 3 | 0 | 3 |
| CMTR2 | ITCH | 0.728173 | 4 | 0 | 4 |
| CMTR2 | RIOK3 | 0.721589 | 3 | 0 | 3 |
| CMTR2 | CAPZA2 | 0.720645 | 3 | 0 | 3 |
| CMTR2 | SH3GLB1 | 0.716801 | 4 | 0 | 4 |
| CMTR2 | SCYL2 | 0.716731 | 4 | 0 | 3 |
| CMTR2 | LY6G6C | 0.71187 | 3 | 0 | 3 |
| CMTR2 | SPTLC1 | 0.707951 | 3 | 0 | 3 |
| CMTR2 | STX11 | 0.707773 | 3 | 0 | 3 |
| CMTR2 | UPRT | 0.707735 | 3 | 0 | 3 |
| CMTR2 | UNC13B | 0.707014 | 3 | 0 | 3 |
| CMTR2 | VAMP7 | 0.703558 | 3 | 0 | 3 |
For details and further investigation, click here
