| Full name: autophagy related 13 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 11p11.2 | ||
| Entrez ID: 9776 | HGNC ID: HGNC:29091 | Ensembl Gene: ENSG00000175224 | OMIM ID: 615088 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
ATG13 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04211 | Longevity regulating pathway - mammal |
Expression of ATG13:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ATG13 | 9776 | 209021_x_at | -0.0961 | 0.8295 | |
| GSE20347 | ATG13 | 9776 | 209021_x_at | -0.1148 | 0.2022 | |
| GSE23400 | ATG13 | 9776 | 209021_x_at | -0.1402 | 0.0009 | |
| GSE26886 | ATG13 | 9776 | 209021_x_at | -0.1030 | 0.6658 | |
| GSE29001 | ATG13 | 9776 | 209021_x_at | -0.4692 | 0.0456 | |
| GSE38129 | ATG13 | 9776 | 203364_s_at | 0.0316 | 0.7692 | |
| GSE45670 | ATG13 | 9776 | 203364_s_at | 0.1825 | 0.1500 | |
| GSE53622 | ATG13 | 9776 | 43077 | 0.2141 | 0.0005 | |
| GSE53624 | ATG13 | 9776 | 43077 | 0.2331 | 0.0001 | |
| GSE63941 | ATG13 | 9776 | 209021_x_at | 0.8444 | 0.0387 | |
| GSE77861 | ATG13 | 9776 | 209021_x_at | -0.1833 | 0.2501 | |
| GSE97050 | ATG13 | 9776 | A_33_P3263696 | 0.3795 | 0.1666 | |
| SRP007169 | ATG13 | 9776 | RNAseq | -1.0059 | 0.0100 | |
| SRP008496 | ATG13 | 9776 | RNAseq | -0.7332 | 0.0009 | |
| SRP064894 | ATG13 | 9776 | RNAseq | 0.0589 | 0.6849 | |
| SRP133303 | ATG13 | 9776 | RNAseq | 0.1731 | 0.2346 | |
| SRP159526 | ATG13 | 9776 | RNAseq | 0.0025 | 0.9930 | |
| SRP193095 | ATG13 | 9776 | RNAseq | -0.1404 | 0.3120 | |
| SRP219564 | ATG13 | 9776 | RNAseq | -0.0272 | 0.9163 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by ATG13 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of ATG13:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ATG13 | 9776 | 3 | 7 | 20 | |
| GSE20123 | ATG13 | 9776 | 3 | 6 | 21 | |
| GSE43470 | ATG13 | 9776 | 2 | 5 | 36 | |
| GSE46452 | ATG13 | 9776 | 8 | 5 | 46 | |
| GSE47630 | ATG13 | 9776 | 3 | 9 | 28 | |
| GSE54993 | ATG13 | 9776 | 3 | 0 | 67 | |
| GSE54994 | ATG13 | 9776 | 1 | 10 | 42 | |
| GSE60625 | ATG13 | 9776 | 0 | 0 | 11 | |
| GSE74703 | ATG13 | 9776 | 2 | 2 | 32 | |
| GSE74704 | ATG13 | 9776 | 2 | 4 | 14 | |
| TCGA | ATG13 | 9776 | 13 | 19 | 64 |
Total number of gains: 40; Total number of losses: 67; Total Number of normals: 381.
Somatic mutations of ATG13:
Generating mutation plots.
Highly correlated genes for ATG13:
Showing top 20/211 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ATG13 | COL23A1 | 0.801558 | 3 | 0 | 3 |
| ATG13 | MFAP3 | 0.770985 | 3 | 0 | 3 |
| ATG13 | METRNL | 0.764749 | 3 | 0 | 3 |
| ATG13 | SLC35A4 | 0.753178 | 3 | 0 | 3 |
| ATG13 | KDM5C | 0.752274 | 3 | 0 | 3 |
| ATG13 | SPIC | 0.738302 | 3 | 0 | 3 |
| ATG13 | FYTTD1 | 0.725922 | 3 | 0 | 3 |
| ATG13 | CR1L | 0.725135 | 3 | 0 | 3 |
| ATG13 | SNX20 | 0.714655 | 3 | 0 | 3 |
| ATG13 | RAD23B | 0.71304 | 4 | 0 | 4 |
| ATG13 | RAB5A | 0.70901 | 3 | 0 | 3 |
| ATG13 | SERPINA12 | 0.707617 | 3 | 0 | 3 |
| ATG13 | MYO1F | 0.707008 | 3 | 0 | 3 |
| ATG13 | MRPL30 | 0.706748 | 3 | 0 | 3 |
| ATG13 | RAB11B | 0.705599 | 3 | 0 | 3 |
| ATG13 | SCYL2 | 0.705539 | 3 | 0 | 3 |
| ATG13 | RHOH | 0.700158 | 3 | 0 | 3 |
| ATG13 | NDUFB3 | 0.695053 | 3 | 0 | 3 |
| ATG13 | NCF4 | 0.694557 | 3 | 0 | 3 |
| ATG13 | AIMP1 | 0.693198 | 3 | 0 | 3 |
For details and further investigation, click here
