| Full name: sidekick cell adhesion molecule 2 | Alias Symbol: FLJ10832|KIAA1514 | ||
| Type: protein-coding gene | Cytoband: 17q25.1 | ||
| Entrez ID: 54549 | HGNC ID: HGNC:19308 | Ensembl Gene: ENSG00000069188 | OMIM ID: 607217 |
| Drug and gene relationship at DGIdb | |||
Expression of SDK2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SDK2 | 54549 | 242064_at | 0.1359 | 0.9056 | |
| GSE20347 | SDK2 | 54549 | 220628_s_at | 0.0484 | 0.5457 | |
| GSE23400 | SDK2 | 54549 | 220628_s_at | -0.0745 | 0.0172 | |
| GSE26886 | SDK2 | 54549 | 233585_at | 0.0074 | 0.9616 | |
| GSE29001 | SDK2 | 54549 | 220628_s_at | -0.0044 | 0.9834 | |
| GSE38129 | SDK2 | 54549 | 220628_s_at | 0.0285 | 0.6742 | |
| GSE45670 | SDK2 | 54549 | 242064_at | 0.8178 | 0.0544 | |
| GSE53622 | SDK2 | 54549 | 37316 | 1.1676 | 0.0000 | |
| GSE53624 | SDK2 | 54549 | 37316 | 1.0505 | 0.0000 | |
| GSE63941 | SDK2 | 54549 | 233585_at | 0.2934 | 0.0516 | |
| GSE77861 | SDK2 | 54549 | 233585_at | -0.0382 | 0.7502 | |
| GSE97050 | SDK2 | 54549 | A_24_P108262 | 0.8549 | 0.1143 | |
| SRP007169 | SDK2 | 54549 | RNAseq | 2.8502 | 0.0030 | |
| SRP064894 | SDK2 | 54549 | RNAseq | 1.5505 | 0.0013 | |
| SRP133303 | SDK2 | 54549 | RNAseq | 1.3357 | 0.0030 | |
| SRP159526 | SDK2 | 54549 | RNAseq | 0.5584 | 0.1350 | |
| SRP193095 | SDK2 | 54549 | RNAseq | 1.4878 | 0.0000 | |
| SRP219564 | SDK2 | 54549 | RNAseq | 1.2474 | 0.1018 | |
| TCGA | SDK2 | 54549 | RNAseq | 0.5257 | 0.0203 |
Upregulated datasets: 6; Downregulated datasets: 0.
Survival by SDK2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SDK2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SDK2 | 54549 | 3 | 2 | 25 | |
| GSE20123 | SDK2 | 54549 | 3 | 2 | 25 | |
| GSE43470 | SDK2 | 54549 | 6 | 3 | 34 | |
| GSE46452 | SDK2 | 54549 | 33 | 0 | 26 | |
| GSE47630 | SDK2 | 54549 | 8 | 1 | 31 | |
| GSE54993 | SDK2 | 54549 | 2 | 5 | 63 | |
| GSE54994 | SDK2 | 54549 | 10 | 5 | 38 | |
| GSE60625 | SDK2 | 54549 | 6 | 0 | 5 | |
| GSE74703 | SDK2 | 54549 | 6 | 1 | 29 | |
| GSE74704 | SDK2 | 54549 | 3 | 2 | 15 | |
| TCGA | SDK2 | 54549 | 32 | 10 | 54 |
Total number of gains: 112; Total number of losses: 31; Total Number of normals: 345.
Somatic mutations of SDK2:
Generating mutation plots.
Highly correlated genes for SDK2:
Showing top 20/392 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SDK2 | TUBA4A | 0.686006 | 3 | 0 | 3 |
| SDK2 | PRKAR1B | 0.6792 | 3 | 0 | 3 |
| SDK2 | PDE3B | 0.670632 | 3 | 0 | 3 |
| SDK2 | KRT6B | 0.66492 | 3 | 0 | 3 |
| SDK2 | MYCBPAP | 0.650185 | 3 | 0 | 3 |
| SDK2 | BTBD2 | 0.648844 | 4 | 0 | 4 |
| SDK2 | BCAN | 0.64115 | 6 | 0 | 5 |
| SDK2 | ANHX | 0.638296 | 4 | 0 | 3 |
| SDK2 | SLC10A1 | 0.637234 | 5 | 0 | 5 |
| SDK2 | NUTM1 | 0.636779 | 4 | 0 | 3 |
| SDK2 | NCR2 | 0.634283 | 7 | 0 | 6 |
| SDK2 | TSGA13 | 0.630154 | 3 | 0 | 3 |
| SDK2 | TAC3 | 0.627776 | 4 | 0 | 3 |
| SDK2 | RASGRF1 | 0.626671 | 5 | 0 | 4 |
| SDK2 | KIR2DS1 | 0.626356 | 6 | 0 | 6 |
| SDK2 | OR10H3 | 0.621893 | 5 | 0 | 5 |
| SDK2 | GALNT8 | 0.621741 | 4 | 0 | 3 |
| SDK2 | EVX1 | 0.621244 | 4 | 0 | 4 |
| SDK2 | IRX4 | 0.620386 | 4 | 0 | 3 |
| SDK2 | KRT38 | 0.618787 | 4 | 0 | 3 |
For details and further investigation, click here
