| Full name: NADH:ubiquinone oxidoreductase core subunit V2 | Alias Symbol: CI-24k | ||
| Type: protein-coding gene | Cytoband: 18p11.22 | ||
| Entrez ID: 4729 | HGNC ID: HGNC:7717 | Ensembl Gene: ENSG00000178127 | OMIM ID: 600532 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of NDUFV2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NDUFV2 | 4729 | 202941_at | -0.2477 | 0.7029 | |
| GSE20347 | NDUFV2 | 4729 | 202941_at | -0.4211 | 0.0248 | |
| GSE23400 | NDUFV2 | 4729 | 202941_at | -0.1620 | 0.0558 | |
| GSE26886 | NDUFV2 | 4729 | 202941_at | -0.2053 | 0.3887 | |
| GSE29001 | NDUFV2 | 4729 | 202941_at | -0.4845 | 0.1490 | |
| GSE38129 | NDUFV2 | 4729 | 202941_at | -0.3043 | 0.0491 | |
| GSE45670 | NDUFV2 | 4729 | 202941_at | -0.2064 | 0.0460 | |
| GSE63941 | NDUFV2 | 4729 | 202941_at | -0.1620 | 0.8113 | |
| GSE77861 | NDUFV2 | 4729 | 202941_at | -0.2856 | 0.1997 | |
| GSE97050 | NDUFV2 | 4729 | A_23_P130418 | -0.4013 | 0.2290 | |
| SRP007169 | NDUFV2 | 4729 | RNAseq | -1.1393 | 0.0001 | |
| SRP008496 | NDUFV2 | 4729 | RNAseq | -1.2102 | 0.0000 | |
| SRP064894 | NDUFV2 | 4729 | RNAseq | -0.4236 | 0.0229 | |
| SRP133303 | NDUFV2 | 4729 | RNAseq | -0.0522 | 0.7630 | |
| SRP159526 | NDUFV2 | 4729 | RNAseq | -0.2653 | 0.3251 | |
| SRP193095 | NDUFV2 | 4729 | RNAseq | -0.5843 | 0.0001 | |
| SRP219564 | NDUFV2 | 4729 | RNAseq | -0.6267 | 0.0398 | |
| TCGA | NDUFV2 | 4729 | RNAseq | -0.0938 | 0.1039 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by NDUFV2 expression:
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| TCGA |
Note: Click image to view full size file.
Copy number change of NDUFV2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NDUFV2 | 4729 | 6 | 3 | 21 | |
| GSE20123 | NDUFV2 | 4729 | 6 | 3 | 21 | |
| GSE43470 | NDUFV2 | 4729 | 3 | 5 | 35 | |
| GSE46452 | NDUFV2 | 4729 | 3 | 21 | 35 | |
| GSE47630 | NDUFV2 | 4729 | 7 | 17 | 16 | |
| GSE54993 | NDUFV2 | 4729 | 6 | 3 | 61 | |
| GSE54994 | NDUFV2 | 4729 | 9 | 8 | 36 | |
| GSE60625 | NDUFV2 | 4729 | 0 | 4 | 7 | |
| GSE74703 | NDUFV2 | 4729 | 2 | 3 | 31 | |
| GSE74704 | NDUFV2 | 4729 | 4 | 2 | 14 | |
| TCGA | NDUFV2 | 4729 | 29 | 23 | 44 |
Total number of gains: 75; Total number of losses: 92; Total Number of normals: 321.
Somatic mutations of NDUFV2:
Generating mutation plots.
Highly correlated genes for NDUFV2:
Showing top 20/429 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NDUFV2 | AMOTL2 | 0.772223 | 3 | 0 | 3 |
| NDUFV2 | AK3 | 0.759921 | 3 | 0 | 3 |
| NDUFV2 | SEC22B | 0.759499 | 3 | 0 | 3 |
| NDUFV2 | RAB12 | 0.758637 | 3 | 0 | 3 |
| NDUFV2 | ANKRD13A | 0.742185 | 3 | 0 | 3 |
| NDUFV2 | AKAP9 | 0.737576 | 3 | 0 | 3 |
| NDUFV2 | PSMG2 | 0.73586 | 10 | 0 | 10 |
| NDUFV2 | CLIP4 | 0.733799 | 3 | 0 | 3 |
| NDUFV2 | USP14 | 0.731432 | 3 | 0 | 3 |
| NDUFV2 | CETN3 | 0.722175 | 3 | 0 | 3 |
| NDUFV2 | RAB13 | 0.718493 | 3 | 0 | 3 |
| NDUFV2 | ATF7IP | 0.710815 | 3 | 0 | 3 |
| NDUFV2 | BBIP1 | 0.709006 | 4 | 0 | 4 |
| NDUFV2 | GOLPH3L | 0.70596 | 3 | 0 | 3 |
| NDUFV2 | MAPK1 | 0.699135 | 3 | 0 | 3 |
| NDUFV2 | CHCHD1 | 0.69607 | 4 | 0 | 3 |
| NDUFV2 | NMNAT1 | 0.695347 | 3 | 0 | 3 |
| NDUFV2 | CREG1 | 0.695033 | 4 | 0 | 4 |
| NDUFV2 | SETMAR | 0.693306 | 3 | 0 | 3 |
| NDUFV2 | USP54 | 0.692668 | 3 | 0 | 3 |
For details and further investigation, click here
