| Full name: RB1 inducible coiled-coil 1 | Alias Symbol: KIAA0203|Cc1|DRAGOU14|FIP200|ATG17|PPP1R131 | ||
| Type: protein-coding gene | Cytoband: 8q11.23 | ||
| Entrez ID: 9821 | HGNC ID: HGNC:15574 | Ensembl Gene: ENSG00000023287 | OMIM ID: 606837 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
RB1CC1 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04211 | Longevity regulating pathway - mammal |
Expression of RB1CC1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RB1CC1 | 9821 | 202033_s_at | 0.2112 | 0.6839 | |
| GSE20347 | RB1CC1 | 9821 | 202033_s_at | 0.3161 | 0.1329 | |
| GSE23400 | RB1CC1 | 9821 | 202033_s_at | 0.1081 | 0.3646 | |
| GSE26886 | RB1CC1 | 9821 | 202033_s_at | -0.1721 | 0.5292 | |
| GSE29001 | RB1CC1 | 9821 | 202033_s_at | -0.1030 | 0.8276 | |
| GSE38129 | RB1CC1 | 9821 | 202033_s_at | 0.2213 | 0.3243 | |
| GSE45670 | RB1CC1 | 9821 | 202033_s_at | -0.0332 | 0.8668 | |
| GSE53622 | RB1CC1 | 9821 | 43681 | 0.0248 | 0.7293 | |
| GSE53624 | RB1CC1 | 9821 | 43681 | 0.0705 | 0.2979 | |
| GSE63941 | RB1CC1 | 9821 | 202033_s_at | -0.3563 | 0.5712 | |
| GSE77861 | RB1CC1 | 9821 | 202033_s_at | 0.1144 | 0.8087 | |
| GSE97050 | RB1CC1 | 9821 | A_23_P9056 | -0.3683 | 0.2179 | |
| SRP007169 | RB1CC1 | 9821 | RNAseq | -0.2019 | 0.5654 | |
| SRP008496 | RB1CC1 | 9821 | RNAseq | -0.2292 | 0.3006 | |
| SRP064894 | RB1CC1 | 9821 | RNAseq | -0.1879 | 0.4297 | |
| SRP133303 | RB1CC1 | 9821 | RNAseq | 0.1062 | 0.3350 | |
| SRP159526 | RB1CC1 | 9821 | RNAseq | 0.2541 | 0.3141 | |
| SRP193095 | RB1CC1 | 9821 | RNAseq | -0.2007 | 0.1028 | |
| SRP219564 | RB1CC1 | 9821 | RNAseq | -0.2626 | 0.4738 | |
| TCGA | RB1CC1 | 9821 | RNAseq | -0.0150 | 0.7781 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RB1CC1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RB1CC1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RB1CC1 | 9821 | 15 | 2 | 13 | |
| GSE20123 | RB1CC1 | 9821 | 15 | 2 | 13 | |
| GSE43470 | RB1CC1 | 9821 | 14 | 3 | 26 | |
| GSE46452 | RB1CC1 | 9821 | 21 | 3 | 35 | |
| GSE47630 | RB1CC1 | 9821 | 23 | 1 | 16 | |
| GSE54993 | RB1CC1 | 9821 | 1 | 16 | 53 | |
| GSE54994 | RB1CC1 | 9821 | 28 | 0 | 25 | |
| GSE60625 | RB1CC1 | 9821 | 0 | 4 | 7 | |
| GSE74703 | RB1CC1 | 9821 | 13 | 2 | 21 | |
| GSE74704 | RB1CC1 | 9821 | 11 | 0 | 9 | |
| TCGA | RB1CC1 | 9821 | 43 | 9 | 44 |
Total number of gains: 184; Total number of losses: 42; Total Number of normals: 262.
Somatic mutations of RB1CC1:
Generating mutation plots.
Highly correlated genes for RB1CC1:
Showing top 20/248 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RB1CC1 | METTL8 | 0.782615 | 3 | 0 | 3 |
| RB1CC1 | BCL9 | 0.77073 | 3 | 0 | 3 |
| RB1CC1 | UTP3 | 0.768731 | 3 | 0 | 3 |
| RB1CC1 | ZNF565 | 0.756897 | 3 | 0 | 3 |
| RB1CC1 | RBPJ | 0.747785 | 3 | 0 | 3 |
| RB1CC1 | NPRL2 | 0.743265 | 3 | 0 | 3 |
| RB1CC1 | SS18 | 0.735466 | 3 | 0 | 3 |
| RB1CC1 | TUBE1 | 0.731524 | 4 | 0 | 4 |
| RB1CC1 | RLIM | 0.728608 | 3 | 0 | 3 |
| RB1CC1 | METTL14 | 0.724592 | 4 | 0 | 3 |
| RB1CC1 | C9orf64 | 0.721663 | 3 | 0 | 3 |
| RB1CC1 | NOP58 | 0.717777 | 3 | 0 | 3 |
| RB1CC1 | VGLL4 | 0.710865 | 4 | 0 | 4 |
| RB1CC1 | SEC22B | 0.707262 | 3 | 0 | 3 |
| RB1CC1 | RCN1 | 0.705315 | 3 | 0 | 3 |
| RB1CC1 | SCRN3 | 0.702783 | 3 | 0 | 3 |
| RB1CC1 | GPATCH1 | 0.700527 | 3 | 0 | 3 |
| RB1CC1 | BUD31 | 0.699337 | 3 | 0 | 3 |
| RB1CC1 | GRB14 | 0.699275 | 3 | 0 | 3 |
| RB1CC1 | HSD17B11 | 0.69073 | 3 | 0 | 3 |
For details and further investigation, click here
