| Full name: striatin 3 | Alias Symbol: SG2NA|PPP2R6B|S/G2NA | ||
| Type: protein-coding gene | Cytoband: 14q12 | ||
| Entrez ID: 29966 | HGNC ID: HGNC:15720 | Ensembl Gene: ENSG00000196792 | OMIM ID: 614766 |
| Drug and gene relationship at DGIdb | |||
Expression of STRN3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | STRN3 | 29966 | 204496_at | 0.5851 | 0.3793 | |
| GSE20347 | STRN3 | 29966 | 204496_at | 0.7080 | 0.0051 | |
| GSE23400 | STRN3 | 29966 | 204496_at | 0.7222 | 0.0000 | |
| GSE26886 | STRN3 | 29966 | 204496_at | 0.4534 | 0.0720 | |
| GSE29001 | STRN3 | 29966 | 204496_at | 0.7673 | 0.0150 | |
| GSE38129 | STRN3 | 29966 | 204496_at | 0.4156 | 0.0229 | |
| GSE45670 | STRN3 | 29966 | 204496_at | 0.7300 | 0.0001 | |
| GSE53622 | STRN3 | 29966 | 128304 | 0.3611 | 0.0003 | |
| GSE53624 | STRN3 | 29966 | 54432 | 0.4019 | 0.0000 | |
| GSE63941 | STRN3 | 29966 | 204496_at | 0.2707 | 0.6145 | |
| GSE77861 | STRN3 | 29966 | 204496_at | 1.2213 | 0.0079 | |
| GSE97050 | STRN3 | 29966 | A_23_P392076 | 0.4056 | 0.3439 | |
| SRP007169 | STRN3 | 29966 | RNAseq | 1.7500 | 0.0000 | |
| SRP008496 | STRN3 | 29966 | RNAseq | 1.4416 | 0.0001 | |
| SRP064894 | STRN3 | 29966 | RNAseq | 0.6285 | 0.0125 | |
| SRP133303 | STRN3 | 29966 | RNAseq | 1.0127 | 0.0001 | |
| SRP159526 | STRN3 | 29966 | RNAseq | 0.3605 | 0.3377 | |
| SRP193095 | STRN3 | 29966 | RNAseq | 0.5480 | 0.0000 | |
| SRP219564 | STRN3 | 29966 | RNAseq | 0.1229 | 0.6767 | |
| TCGA | STRN3 | 29966 | RNAseq | 0.0128 | 0.8371 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by STRN3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of STRN3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | STRN3 | 29966 | 9 | 4 | 17 | |
| GSE20123 | STRN3 | 29966 | 9 | 4 | 17 | |
| GSE43470 | STRN3 | 29966 | 10 | 2 | 31 | |
| GSE46452 | STRN3 | 29966 | 16 | 2 | 41 | |
| GSE47630 | STRN3 | 29966 | 11 | 10 | 19 | |
| GSE54993 | STRN3 | 29966 | 3 | 11 | 56 | |
| GSE54994 | STRN3 | 29966 | 19 | 5 | 29 | |
| GSE60625 | STRN3 | 29966 | 0 | 2 | 9 | |
| GSE74703 | STRN3 | 29966 | 9 | 2 | 25 | |
| GSE74704 | STRN3 | 29966 | 4 | 3 | 13 | |
| TCGA | STRN3 | 29966 | 33 | 15 | 48 |
Total number of gains: 123; Total number of losses: 60; Total Number of normals: 305.
Somatic mutations of STRN3:
Generating mutation plots.
Highly correlated genes for STRN3:
Showing top 20/1271 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| STRN3 | FAM177A1 | 0.778185 | 3 | 0 | 3 |
| STRN3 | FAM168B | 0.764425 | 3 | 0 | 3 |
| STRN3 | CDC42SE2 | 0.757269 | 3 | 0 | 3 |
| STRN3 | LYAR | 0.753846 | 3 | 0 | 3 |
| STRN3 | MRPL47 | 0.732857 | 5 | 0 | 4 |
| STRN3 | MASTL | 0.732204 | 4 | 0 | 4 |
| STRN3 | SDHAF2 | 0.727915 | 3 | 0 | 3 |
| STRN3 | ST13 | 0.720474 | 3 | 0 | 3 |
| STRN3 | PARP14 | 0.716791 | 3 | 0 | 3 |
| STRN3 | MNAT1 | 0.715326 | 11 | 0 | 11 |
| STRN3 | SEC63 | 0.715193 | 3 | 0 | 3 |
| STRN3 | CDC25A | 0.713379 | 3 | 0 | 3 |
| STRN3 | SOCS4 | 0.713244 | 7 | 0 | 6 |
| STRN3 | COCH | 0.70986 | 8 | 0 | 6 |
| STRN3 | YWHAG | 0.707755 | 5 | 0 | 4 |
| STRN3 | RAP2B | 0.706517 | 3 | 0 | 3 |
| STRN3 | DTD2 | 0.7045 | 5 | 0 | 4 |
| STRN3 | LRRC58 | 0.702383 | 5 | 0 | 4 |
| STRN3 | COX16 | 0.698981 | 3 | 0 | 3 |
| STRN3 | SEC23A | 0.698921 | 11 | 0 | 10 |
For details and further investigation, click here
