| Full name: solute carrier family 15 member 4 | Alias Symbol: PHT1|PTR4 | ||
| Type: protein-coding gene | Cytoband: 12q24.33 | ||
| Entrez ID: 121260 | HGNC ID: HGNC:23090 | Ensembl Gene: ENSG00000139370 | OMIM ID: 615806 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC15A4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC15A4 | 121260 | 225057_at | 0.1650 | 0.5857 | |
| GSE26886 | SLC15A4 | 121260 | 225043_at | 0.4313 | 0.0420 | |
| GSE45670 | SLC15A4 | 121260 | 225057_at | 0.0376 | 0.8623 | |
| GSE53622 | SLC15A4 | 121260 | 65886 | 0.6338 | 0.0000 | |
| GSE53624 | SLC15A4 | 121260 | 22142 | -0.9588 | 0.0000 | |
| GSE63941 | SLC15A4 | 121260 | 225057_at | -1.2098 | 0.0032 | |
| GSE77861 | SLC15A4 | 121260 | 225043_at | 0.2983 | 0.0468 | |
| GSE97050 | SLC15A4 | 121260 | A_24_P13311 | 0.3941 | 0.2194 | |
| SRP007169 | SLC15A4 | 121260 | RNAseq | 0.2640 | 0.5004 | |
| SRP008496 | SLC15A4 | 121260 | RNAseq | 0.0866 | 0.7165 | |
| SRP064894 | SLC15A4 | 121260 | RNAseq | 0.5371 | 0.0014 | |
| SRP133303 | SLC15A4 | 121260 | RNAseq | 0.6240 | 0.0051 | |
| SRP159526 | SLC15A4 | 121260 | RNAseq | 0.0076 | 0.9643 | |
| SRP193095 | SLC15A4 | 121260 | RNAseq | 0.4171 | 0.0001 | |
| SRP219564 | SLC15A4 | 121260 | RNAseq | 0.1817 | 0.5320 | |
| TCGA | SLC15A4 | 121260 | RNAseq | 0.0881 | 0.1071 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by SLC15A4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC15A4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC15A4 | 121260 | 3 | 4 | 23 | |
| GSE20123 | SLC15A4 | 121260 | 3 | 4 | 23 | |
| GSE43470 | SLC15A4 | 121260 | 2 | 0 | 41 | |
| GSE46452 | SLC15A4 | 121260 | 9 | 1 | 49 | |
| GSE47630 | SLC15A4 | 121260 | 9 | 3 | 28 | |
| GSE54993 | SLC15A4 | 121260 | 0 | 5 | 65 | |
| GSE54994 | SLC15A4 | 121260 | 4 | 7 | 42 | |
| GSE60625 | SLC15A4 | 121260 | 0 | 0 | 11 | |
| GSE74703 | SLC15A4 | 121260 | 2 | 0 | 34 | |
| GSE74704 | SLC15A4 | 121260 | 2 | 3 | 15 | |
| TCGA | SLC15A4 | 121260 | 22 | 13 | 61 |
Total number of gains: 56; Total number of losses: 40; Total Number of normals: 392.
Somatic mutations of SLC15A4:
Generating mutation plots.
Highly correlated genes for SLC15A4:
Showing top 20/421 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC15A4 | STK17A | 0.774869 | 3 | 0 | 3 |
| SLC15A4 | CPT1A | 0.769284 | 3 | 0 | 3 |
| SLC15A4 | PCDH18 | 0.747233 | 3 | 0 | 3 |
| SLC15A4 | IL6 | 0.743147 | 3 | 0 | 3 |
| SLC15A4 | SLC6A15 | 0.738054 | 4 | 0 | 4 |
| SLC15A4 | COPS8 | 0.737247 | 5 | 0 | 5 |
| SLC15A4 | NOM1 | 0.736478 | 3 | 0 | 3 |
| SLC15A4 | PSMC3IP | 0.729641 | 3 | 0 | 3 |
| SLC15A4 | MAN1A1 | 0.720982 | 4 | 0 | 4 |
| SLC15A4 | CYP26B1 | 0.720712 | 3 | 0 | 3 |
| SLC15A4 | PTHLH | 0.716772 | 3 | 0 | 3 |
| SLC15A4 | CEBPZ | 0.716383 | 3 | 0 | 3 |
| SLC15A4 | RPS6KC1 | 0.713558 | 3 | 0 | 3 |
| SLC15A4 | RAD1 | 0.71205 | 3 | 0 | 3 |
| SLC15A4 | SIAH1 | 0.710973 | 4 | 0 | 4 |
| SLC15A4 | TRIM35 | 0.706618 | 3 | 0 | 3 |
| SLC15A4 | SLC25A24 | 0.704957 | 3 | 0 | 3 |
| SLC15A4 | LRRC8A | 0.702192 | 3 | 0 | 3 |
| SLC15A4 | FBXO31 | 0.701315 | 3 | 0 | 3 |
| SLC15A4 | FAM98A | 0.700068 | 3 | 0 | 3 |
For details and further investigation, click here
