| Full name: RTF1 homolog, Paf1/RNA polymerase II complex component | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 15q15.1 | ||
| Entrez ID: 23168 | HGNC ID: HGNC:28996 | Ensembl Gene: ENSG00000137815 | OMIM ID: 611633 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of RTF1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RTF1 | 23168 | 212301_at | -0.2178 | 0.5570 | |
| GSE20347 | RTF1 | 23168 | 212301_at | -0.0261 | 0.8645 | |
| GSE23400 | RTF1 | 23168 | 212301_at | 0.0591 | 0.3761 | |
| GSE26886 | RTF1 | 23168 | 212301_at | -0.1260 | 0.6290 | |
| GSE29001 | RTF1 | 23168 | 212301_at | -0.1151 | 0.6354 | |
| GSE38129 | RTF1 | 23168 | 212301_at | -0.0429 | 0.6876 | |
| GSE45670 | RTF1 | 23168 | 212301_at | -0.3983 | 0.0006 | |
| GSE53622 | RTF1 | 23168 | 47065 | -0.2041 | 0.0011 | |
| GSE53624 | RTF1 | 23168 | 47065 | -0.2022 | 0.0002 | |
| GSE63941 | RTF1 | 23168 | 212301_at | -0.8729 | 0.0038 | |
| GSE77861 | RTF1 | 23168 | 212301_at | 0.0535 | 0.7897 | |
| GSE97050 | RTF1 | 23168 | A_24_P390403 | -0.5359 | 0.0903 | |
| SRP007169 | RTF1 | 23168 | RNAseq | 0.5801 | 0.1215 | |
| SRP008496 | RTF1 | 23168 | RNAseq | 0.4839 | 0.0579 | |
| SRP064894 | RTF1 | 23168 | RNAseq | 0.0558 | 0.7614 | |
| SRP133303 | RTF1 | 23168 | RNAseq | 0.0227 | 0.8343 | |
| SRP159526 | RTF1 | 23168 | RNAseq | 0.0509 | 0.8331 | |
| SRP193095 | RTF1 | 23168 | RNAseq | -0.1094 | 0.1601 | |
| SRP219564 | RTF1 | 23168 | RNAseq | -0.4683 | 0.0597 | |
| TCGA | RTF1 | 23168 | RNAseq | 0.0061 | 0.8887 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RTF1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RTF1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RTF1 | 23168 | 3 | 6 | 21 | |
| GSE20123 | RTF1 | 23168 | 3 | 6 | 21 | |
| GSE43470 | RTF1 | 23168 | 4 | 6 | 33 | |
| GSE46452 | RTF1 | 23168 | 3 | 7 | 49 | |
| GSE47630 | RTF1 | 23168 | 8 | 11 | 21 | |
| GSE54993 | RTF1 | 23168 | 4 | 6 | 60 | |
| GSE54994 | RTF1 | 23168 | 5 | 8 | 40 | |
| GSE60625 | RTF1 | 23168 | 4 | 0 | 7 | |
| GSE74703 | RTF1 | 23168 | 4 | 5 | 27 | |
| GSE74704 | RTF1 | 23168 | 2 | 4 | 14 | |
| TCGA | RTF1 | 23168 | 11 | 18 | 67 |
Total number of gains: 51; Total number of losses: 77; Total Number of normals: 360.
Somatic mutations of RTF1:
Generating mutation plots.
Highly correlated genes for RTF1:
Showing top 20/438 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RTF1 | ARMCX6 | 0.807998 | 3 | 0 | 3 |
| RTF1 | CDIPT | 0.782733 | 3 | 0 | 3 |
| RTF1 | TK2 | 0.777805 | 3 | 0 | 3 |
| RTF1 | RCAN1 | 0.765099 | 3 | 0 | 3 |
| RTF1 | ZBTB44 | 0.762735 | 3 | 0 | 3 |
| RTF1 | USP12 | 0.759822 | 3 | 0 | 3 |
| RTF1 | PIAS2 | 0.755655 | 3 | 0 | 3 |
| RTF1 | MRPL16 | 0.751868 | 3 | 0 | 3 |
| RTF1 | PINK1 | 0.749536 | 3 | 0 | 3 |
| RTF1 | TMEM98 | 0.745248 | 3 | 0 | 3 |
| RTF1 | ZNF347 | 0.733275 | 3 | 0 | 3 |
| RTF1 | CCDC6 | 0.731598 | 3 | 0 | 3 |
| RTF1 | TMEM126B | 0.729808 | 3 | 0 | 3 |
| RTF1 | SLC25A30 | 0.726159 | 3 | 0 | 3 |
| RTF1 | MTCH2 | 0.723806 | 3 | 0 | 3 |
| RTF1 | PLEKHM3 | 0.717987 | 3 | 0 | 3 |
| RTF1 | WWC3 | 0.715305 | 4 | 0 | 4 |
| RTF1 | TRERF1 | 0.713406 | 3 | 0 | 3 |
| RTF1 | NSMCE1 | 0.711468 | 3 | 0 | 3 |
| RTF1 | GNL3 | 0.711209 | 3 | 0 | 3 |
For details and further investigation, click here
