| Full name: zinc finger protein 653 | Alias Symbol: Zip67 | ||
| Type: protein-coding gene | Cytoband: 19p13.2 | ||
| Entrez ID: 115950 | HGNC ID: HGNC:25196 | Ensembl Gene: ENSG00000161914 | OMIM ID: 611371 |
| Drug and gene relationship at DGIdb | |||
Expression of ZNF653:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF653 | 115950 | 228864_at | 0.0493 | 0.9611 | |
| GSE26886 | ZNF653 | 115950 | 244085_at | 0.3556 | 0.0148 | |
| GSE45670 | ZNF653 | 115950 | 244085_at | 0.0192 | 0.8970 | |
| GSE53622 | ZNF653 | 115950 | 54696 | -0.1424 | 0.0383 | |
| GSE53624 | ZNF653 | 115950 | 54696 | 0.2397 | 0.0000 | |
| GSE63941 | ZNF653 | 115950 | 244085_at | 0.1810 | 0.3536 | |
| GSE77861 | ZNF653 | 115950 | 244085_at | -0.1204 | 0.2745 | |
| GSE97050 | ZNF653 | 115950 | A_23_P325676 | 0.0473 | 0.8626 | |
| SRP064894 | ZNF653 | 115950 | RNAseq | 0.6831 | 0.0196 | |
| SRP133303 | ZNF653 | 115950 | RNAseq | -0.1474 | 0.4647 | |
| SRP159526 | ZNF653 | 115950 | RNAseq | 0.2881 | 0.4505 | |
| SRP193095 | ZNF653 | 115950 | RNAseq | 0.0908 | 0.4540 | |
| SRP219564 | ZNF653 | 115950 | RNAseq | 0.5306 | 0.1513 | |
| TCGA | ZNF653 | 115950 | RNAseq | -0.0836 | 0.2403 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ZNF653 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF653:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF653 | 115950 | 4 | 2 | 24 | |
| GSE20123 | ZNF653 | 115950 | 3 | 1 | 26 | |
| GSE43470 | ZNF653 | 115950 | 2 | 6 | 35 | |
| GSE46452 | ZNF653 | 115950 | 47 | 1 | 11 | |
| GSE47630 | ZNF653 | 115950 | 4 | 7 | 29 | |
| GSE54993 | ZNF653 | 115950 | 16 | 3 | 51 | |
| GSE54994 | ZNF653 | 115950 | 6 | 13 | 34 | |
| GSE60625 | ZNF653 | 115950 | 9 | 0 | 2 | |
| GSE74703 | ZNF653 | 115950 | 2 | 4 | 30 | |
| GSE74704 | ZNF653 | 115950 | 0 | 1 | 19 | |
| TCGA | ZNF653 | 115950 | 16 | 12 | 68 |
Total number of gains: 109; Total number of losses: 50; Total Number of normals: 329.
Somatic mutations of ZNF653:
Generating mutation plots.
Highly correlated genes for ZNF653:
Showing top 20/250 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF653 | SH2B1 | 0.775984 | 4 | 0 | 4 |
| ZNF653 | PDE3A | 0.756908 | 3 | 0 | 3 |
| ZNF653 | GATA6 | 0.745619 | 3 | 0 | 3 |
| ZNF653 | THBS4 | 0.73595 | 3 | 0 | 3 |
| ZNF653 | GAS6-AS1 | 0.731498 | 3 | 0 | 3 |
| ZNF653 | CRIP3 | 0.724866 | 3 | 0 | 3 |
| ZNF653 | ZNF771 | 0.715972 | 3 | 0 | 3 |
| ZNF653 | SSC5D | 0.705218 | 3 | 0 | 3 |
| ZNF653 | ZNF574 | 0.703319 | 4 | 0 | 4 |
| ZNF653 | SYNGR3 | 0.699248 | 3 | 0 | 3 |
| ZNF653 | ZDHHC1 | 0.691893 | 4 | 0 | 4 |
| ZNF653 | ADAMTS10 | 0.680269 | 3 | 0 | 3 |
| ZNF653 | LIN37 | 0.679534 | 3 | 0 | 3 |
| ZNF653 | ADARB1 | 0.677844 | 3 | 0 | 3 |
| ZNF653 | WDR25 | 0.67422 | 4 | 0 | 4 |
| ZNF653 | ETV2 | 0.663534 | 3 | 0 | 3 |
| ZNF653 | C16orf86 | 0.66326 | 3 | 0 | 3 |
| ZNF653 | SEMA6B | 0.662413 | 3 | 0 | 3 |
| ZNF653 | TNFRSF9 | 0.661741 | 3 | 0 | 3 |
| ZNF653 | LAT | 0.659741 | 3 | 0 | 3 |
For details and further investigation, click here
