| Full name: serine hydrolase like 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 22q13.2 | ||
| Entrez ID: 253190 | HGNC ID: HGNC:29446 | Ensembl Gene: ENSG00000183569 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of SERHL2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SERHL2 | 253190 | 217276_x_at | -0.1448 | 0.6103 | |
| GSE20347 | SERHL2 | 253190 | 217276_x_at | -0.1643 | 0.0566 | |
| GSE23400 | SERHL2 | 253190 | 217284_x_at | -0.2012 | 0.0000 | |
| GSE26886 | SERHL2 | 253190 | 217276_x_at | -0.2849 | 0.0036 | |
| GSE29001 | SERHL2 | 253190 | 217276_x_at | 0.0534 | 0.7467 | |
| GSE38129 | SERHL2 | 253190 | 217284_x_at | -0.3003 | 0.0004 | |
| GSE45670 | SERHL2 | 253190 | 217276_x_at | -0.3204 | 0.0094 | |
| GSE53622 | SERHL2 | 253190 | 121579 | -0.4293 | 0.0000 | |
| GSE53624 | SERHL2 | 253190 | 43583 | -0.4837 | 0.0001 | |
| GSE63941 | SERHL2 | 253190 | 217276_x_at | 0.1106 | 0.6476 | |
| GSE77861 | SERHL2 | 253190 | 217284_x_at | -0.2049 | 0.1055 | |
| GSE97050 | SERHL2 | 253190 | A_23_P120953 | 0.0522 | 0.8828 | |
| SRP064894 | SERHL2 | 253190 | RNAseq | -0.1607 | 0.5824 | |
| SRP133303 | SERHL2 | 253190 | RNAseq | -0.8104 | 0.0000 | |
| SRP159526 | SERHL2 | 253190 | RNAseq | -0.2466 | 0.6287 | |
| SRP193095 | SERHL2 | 253190 | RNAseq | -0.4110 | 0.0114 | |
| SRP219564 | SERHL2 | 253190 | RNAseq | 0.2026 | 0.6611 | |
| TCGA | SERHL2 | 253190 | RNAseq | -0.3948 | 0.0055 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SERHL2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SERHL2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SERHL2 | 253190 | 6 | 6 | 18 | |
| GSE20123 | SERHL2 | 253190 | 6 | 5 | 19 | |
| GSE43470 | SERHL2 | 253190 | 5 | 6 | 32 | |
| GSE46452 | SERHL2 | 253190 | 31 | 2 | 26 | |
| GSE47630 | SERHL2 | 253190 | 9 | 4 | 27 | |
| GSE54993 | SERHL2 | 253190 | 3 | 6 | 61 | |
| GSE54994 | SERHL2 | 253190 | 11 | 8 | 34 | |
| GSE60625 | SERHL2 | 253190 | 5 | 0 | 6 | |
| GSE74703 | SERHL2 | 253190 | 5 | 4 | 27 | |
| GSE74704 | SERHL2 | 253190 | 3 | 3 | 14 | |
| TCGA | SERHL2 | 253190 | 28 | 13 | 55 |
Total number of gains: 112; Total number of losses: 57; Total Number of normals: 319.
Somatic mutations of SERHL2:
Generating mutation plots.
Highly correlated genes for SERHL2:
Showing top 20/239 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SERHL2 | FAM131C | 0.753851 | 3 | 0 | 3 |
| SERHL2 | LDHAL6A | 0.732391 | 3 | 0 | 3 |
| SERHL2 | SEZ6 | 0.697775 | 3 | 0 | 3 |
| SERHL2 | EXD3 | 0.671417 | 5 | 0 | 4 |
| SERHL2 | ACTR1A | 0.668627 | 3 | 0 | 3 |
| SERHL2 | DCTN1-AS1 | 0.663788 | 3 | 0 | 3 |
| SERHL2 | PPP1R11 | 0.654149 | 3 | 0 | 3 |
| SERHL2 | FAM120C | 0.648492 | 3 | 0 | 3 |
| SERHL2 | CYP46A1 | 0.646627 | 3 | 0 | 3 |
| SERHL2 | PITHD1 | 0.645288 | 3 | 0 | 3 |
| SERHL2 | RBM20 | 0.631554 | 4 | 0 | 4 |
| SERHL2 | RPRML | 0.630148 | 4 | 0 | 3 |
| SERHL2 | PLEKHA7 | 0.627807 | 3 | 0 | 3 |
| SERHL2 | SOX21-AS1 | 0.626643 | 3 | 0 | 3 |
| SERHL2 | CASP9 | 0.62369 | 4 | 0 | 3 |
| SERHL2 | ZNF347 | 0.622416 | 3 | 0 | 3 |
| SERHL2 | LAT2 | 0.620246 | 4 | 0 | 3 |
| SERHL2 | CCIN | 0.619839 | 6 | 0 | 4 |
| SERHL2 | SERAC1 | 0.619128 | 4 | 0 | 3 |
| SERHL2 | ASMTL-AS1 | 0.614286 | 3 | 0 | 3 |
For details and further investigation, click here
