| Full name: serine active site containing 1 | Alias Symbol: FLJ14917 | ||
| Type: protein-coding gene | Cytoband: 6q25.3 | ||
| Entrez ID: 84947 | HGNC ID: HGNC:21061 | Ensembl Gene: ENSG00000122335 | OMIM ID: 614725 |
| Drug and gene relationship at DGIdb | |||
Expression of SERAC1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SERAC1 | 84947 | 232183_at | -0.8433 | 0.1479 | |
| GSE26886 | SERAC1 | 84947 | 232183_at | -1.7077 | 0.0000 | |
| GSE45670 | SERAC1 | 84947 | 232183_at | -0.4707 | 0.0132 | |
| GSE53622 | SERAC1 | 84947 | 78636 | -0.5037 | 0.0000 | |
| GSE53624 | SERAC1 | 84947 | 78636 | -0.8318 | 0.0000 | |
| GSE63941 | SERAC1 | 84947 | 232183_at | -1.3064 | 0.0160 | |
| GSE77861 | SERAC1 | 84947 | 232183_at | -0.7401 | 0.0271 | |
| GSE97050 | SERAC1 | 84947 | A_33_P3777584 | -0.1231 | 0.6706 | |
| SRP007169 | SERAC1 | 84947 | RNAseq | -0.9956 | 0.0433 | |
| SRP008496 | SERAC1 | 84947 | RNAseq | -1.1068 | 0.0001 | |
| SRP064894 | SERAC1 | 84947 | RNAseq | -0.7310 | 0.0014 | |
| SRP133303 | SERAC1 | 84947 | RNAseq | -0.4195 | 0.0129 | |
| SRP159526 | SERAC1 | 84947 | RNAseq | -1.0775 | 0.0032 | |
| SRP193095 | SERAC1 | 84947 | RNAseq | -0.9593 | 0.0000 | |
| SRP219564 | SERAC1 | 84947 | RNAseq | -1.0439 | 0.0007 | |
| TCGA | SERAC1 | 84947 | RNAseq | -0.2987 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 5.
Survival by SERAC1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SERAC1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SERAC1 | 84947 | 2 | 5 | 23 | |
| GSE20123 | SERAC1 | 84947 | 2 | 4 | 24 | |
| GSE43470 | SERAC1 | 84947 | 4 | 0 | 39 | |
| GSE46452 | SERAC1 | 84947 | 3 | 10 | 46 | |
| GSE47630 | SERAC1 | 84947 | 9 | 4 | 27 | |
| GSE54993 | SERAC1 | 84947 | 3 | 2 | 65 | |
| GSE54994 | SERAC1 | 84947 | 8 | 9 | 36 | |
| GSE60625 | SERAC1 | 84947 | 0 | 1 | 10 | |
| GSE74703 | SERAC1 | 84947 | 4 | 0 | 32 | |
| GSE74704 | SERAC1 | 84947 | 0 | 2 | 18 | |
| TCGA | SERAC1 | 84947 | 13 | 22 | 61 |
Total number of gains: 48; Total number of losses: 59; Total Number of normals: 381.
Somatic mutations of SERAC1:
Generating mutation plots.
Highly correlated genes for SERAC1:
Showing top 20/962 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SERAC1 | RBM20 | 0.768639 | 3 | 0 | 3 |
| SERAC1 | PIH1D2 | 0.754111 | 3 | 0 | 3 |
| SERAC1 | TMOD3 | 0.746508 | 6 | 0 | 6 |
| SERAC1 | CHP1 | 0.744867 | 6 | 0 | 6 |
| SERAC1 | RAET1E | 0.741385 | 6 | 0 | 6 |
| SERAC1 | GBP6 | 0.740159 | 4 | 0 | 4 |
| SERAC1 | EMP1 | 0.738554 | 6 | 0 | 6 |
| SERAC1 | TMEM154 | 0.730742 | 6 | 0 | 6 |
| SERAC1 | SNORA68 | 0.72736 | 4 | 0 | 4 |
| SERAC1 | KATNBL1 | 0.725081 | 5 | 0 | 5 |
| SERAC1 | TAB2 | 0.724587 | 4 | 0 | 4 |
| SERAC1 | PSCA | 0.72415 | 4 | 0 | 4 |
| SERAC1 | GYS2 | 0.7241 | 6 | 0 | 6 |
| SERAC1 | IL18 | 0.72177 | 6 | 0 | 6 |
| SERAC1 | RAB10 | 0.720525 | 7 | 0 | 7 |
| SERAC1 | SFTA2 | 0.720318 | 4 | 0 | 4 |
| SERAC1 | GDPD3 | 0.718911 | 7 | 0 | 7 |
| SERAC1 | CYP2C18 | 0.718886 | 6 | 0 | 6 |
| SERAC1 | CYSRT1 | 0.718577 | 6 | 0 | 6 |
| SERAC1 | GCHFR | 0.718332 | 4 | 0 | 4 |
For details and further investigation, click here
